ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	46/481	145/7206	3.6906965817e-20
ko03030	DNA replication	23/481	38/7206	3.34412234982e-18
ko04111	Cell cycle - yeast	33/481	90/7206	6.68359004271e-17
ko04110	Cell cycle	38/481	145/7206	8.28150070518e-14
ko03015	mRNA surveillance pathway	27/481	93/7206	2.77190777977e-11
ko04080	Neuroactive ligand-receptor interaction	2/481	423/7206	7.22656332368e-11
ko04113	Meiosis - yeast	22/481	70/7206	3.62493590164e-10
ko03410	Base excision repair	16/481	38/7206	6.86617885222e-10
ko05217	Basal cell carcinoma	18/481	68/7206	2.81635233029e-07
ko03430	Mismatch repair	10/481	22/7206	4.98924484534e-07
ko04144	Endocytosis	4/481	342/7206	1.13741184279e-06
ko04020	Calcium signaling pathway	2/481	265/7206	3.6049295172e-06
ko03013	RNA transport	28/481	166/7206	4.09145754282e-06
ko04330	Notch signaling pathway	15/481	62/7206	9.36239298958e-06
ko00240	Pyrimidine metabolism	21/481	110/7206	9.42850955045e-06
ko04950	Maturity onset diabetes of the young	10/481	29/7206	1.0088217737e-05
ko04550	Signaling pathways regulating pluripotency of stem cells	27/481	165/7206	1.08905652528e-05
ko04340	Hedgehog signaling pathway	14/481	58/7206	1.91185461936e-05
ko04072	Phospholipase D signaling pathway	1/481	197/7206	3.11360985108e-05
ko03420	Nucleotide excision repair	12/481	46/7206	3.27682781617e-05
ko04060	Cytokine-cytokine receptor interaction	1/481	191/7206	4.60195889e-05
ko05166	HTLV-I infection	38/481	292/7206	5.94929036185e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	1/481	182/7206	6.67181334023e-05
ko04723	Retrograde endocannabinoid signaling	1/481	175/7206	0.000154075385036
ko04310	Wnt signaling pathway	26/481	181/7206	0.000199020330822
ko05224	Breast cancer	25/481	174/7206	0.00027603311305
ko05012	Parkinson's disease	1/481	155/7206	0.00047061195243
ko04921	Oxytocin signaling pathway	3/481	209/7206	0.000605420296142
ko04371	Apelin signaling pathway	2/481	177/7206	0.00067766718932
ko04062	Chemokine signaling pathway	3/481	201/7206	0.000853338681793
ko04390	Hippo signaling pathway	25/481	188/7206	0.000887868358547
ko04725	Cholinergic synapse	2/481	160/7206	0.00202077474013
ko03010	Ribosome	1/481	129/7206	0.00214613262552
ko04141	Protein processing in endoplasmic reticulum	3/481	184/7206	0.00243052796468
ko04270	Vascular smooth muscle contraction	2/481	154/7206	0.0028962070291
ko04621	NOD-like receptor signaling pathway	2/481	157/7206	0.00299998969772
ko04066	HIF-1 signaling pathway	1/481	123/7206	0.00313709823705
ko00190	Oxidative phosphorylation	1/481	127/7206	0.00327999926453
ko04912	GnRH signaling pathway	1/481	122/7206	0.00489698610178
ko04114	Oocyte meiosis	18/481	139/7206	0.0056002385097
ko05414	Dilated cardiomyopathy	1/481	112/7206	0.00669405377907
ko00230	Purine metabolism	23/481	194/7206	0.00773592574778
ko05231	Choline metabolism in cancer	2/481	134/7206	0.00838267025318
ko04727	GABAergic synapse	1/481	110/7206	0.0103572175023
ko05032	Morphine addiction	1/481	110/7206	0.0103572175023
ko04922	Glucagon signaling pathway	2/481	128/7206	0.0118935483013
ko04915	Estrogen signaling pathway	2/481	131/7206	0.0120591921195
ko05100	Bacterial invasion of epithelial cells	1/481	99/7206	0.0141072204329
ko05410	Hypertrophic cardiomyopathy (HCM)	1/481	100/7206	0.014153211805
ko04620	Toll-like receptor signaling pathway	1/481	100/7206	0.014153211805
ko04014	Ras signaling pathway	9/481	279/7206	0.014230363835
ko05202	Transcriptional misregulation in cancer	21/481	188/7206	0.0173197633484
ko04612	Antigen processing and presentation	11/481	77/7206	0.0174037677563
ko04022	cGMP-PKG signaling pathway	6/481	216/7206	0.0175841795814
ko03460	Fanconi anemia pathway	8/481	51/7206	0.0186526783748
ko04970	Salivary secretion	1/481	95/7206	0.0206936176437
ko04260	Cardiac muscle contraction	1/481	98/7206	0.0217710253244
ko04071	Sphingolipid signaling pathway	4/481	162/7206	0.025058421137
ko04611	Platelet activation	4/481	163/7206	0.0251371732148
ko04010	MAPK signaling pathway	12/481	321/7206	0.0292073999842
ko04360	Axon guidance	24/481	233/7206	0.0317185770909
ko04012	ErbB signaling pathway	2/481	109/7206	0.0334341046268
ko04972	Pancreatic secretion	2/481	111/7206	0.0335009245916
ko04070	Phosphatidylinositol signaling system	2/481	112/7206	0.0337059965172
ko04630	Jak-STAT signaling pathway	3/481	132/7206	0.0344797943334
ko04380	Osteoclast differentiation	3/481	134/7206	0.0345989852805
ko04722	Neurotrophin signaling pathway	4/481	160/7206	0.0350434407939
ko04713	Circadian entrainment	3/481	136/7206	0.0351079087662
ko04120	Ubiquitin mediated proteolysis	16/481	138/7206	0.0360060206851
ko04015	Rap1 signaling pathway	10/481	278/7206	0.0362833469591
ko04024	cAMP signaling pathway	10/481	279/7206	0.036440340536
ko03020	RNA polymerase	5/481	29/7206	0.0407163365744
ko04721	Synaptic vesicle cycle	1/481	80/7206	0.042763964717
ko04976	Bile secretion	1/481	80/7206	0.042763964717
ko04740	Olfactory transduction	1/481	80/7206	0.042763964717
ko04910	Insulin signaling pathway	5/481	172/7206	0.0434608557088
ko05206	MicroRNAs in cancer	19/481	177/7206	0.0450939573449
ko04218	Cellular senescence	19/481	177/7206	0.0450939573449
ko05160	Hepatitis C	4/481	153/7206	0.0469346626547
ko04925	Aldosterone synthesis and secretion	2/481	105/7206	0.0470068158407
ko05145	Toxoplasmosis	3/481	126/7206	0.0473017772144
ko04659	Th17 cell differentiation	2/481	106/7206	0.0473164499791
ko01200	Carbon metabolism	3/481	128/7206	0.0475445070169
ko05142	Chagas disease (American trypanosomiasis)	3/481	130/7206	0.0482878326358
ko05222	Small cell lung cancer	11/481	89/7206	0.0491718832591