ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	94/483	423/7206	3.69846947234e-27
ko04724	Glutamatergic synapse	52/483	152/7206	2.44250418944e-24
ko05033	Nicotine addiction	28/483	56/7206	8.44104788556e-19
ko05032	Morphine addiction	34/483	110/7206	9.7306309706e-15
ko04713	Circadian entrainment	38/483	136/7206	9.86187984852e-15
ko04723	Retrograde endocannabinoid signaling	43/483	175/7206	2.48337243711e-14
ko04727	GABAergic synapse	33/483	110/7206	6.39559126274e-14
ko04728	Dopaminergic synapse	40/483	185/7206	1.69736892854e-11
ko04024	cAMP signaling pathway	51/483	279/7206	2.10855355206e-11
ko04720	Long-term potentiation	28/483	99/7206	2.61100489356e-11
ko04721	Synaptic vesicle cycle	24/483	80/7206	1.83613623e-10
ko04921	Oxytocin signaling pathway	41/483	209/7206	2.36981325735e-10
ko04911	Insulin secretion	29/483	117/7206	3.80368057792e-10
ko05031	Amphetamine addiction	25/483	91/7206	6.14978400046e-10
ko05030	Cocaine addiction	22/483	73/7206	9.69683003038e-10
ko04020	Calcium signaling pathway	45/483	265/7206	4.05014236837e-09
ko04261	Adrenergic signaling in cardiomyocytes	36/483	205/7206	6.48980194174e-08
ko04970	Salivary secretion	21/483	95/7206	8.41010118269e-07
ko04742	Taste transduction	16/483	61/7206	1.56994764285e-06
ko04726	Serotonergic synapse	25/483	137/7206	3.41103872401e-06
ko04925	Aldosterone synthesis and secretion	21/483	105/7206	4.67357656278e-06
ko04725	Cholinergic synapse	27/483	160/7206	6.52094271007e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	16/483	74/7206	2.30726981275e-05
ko05203	Viral carcinogenesis	4/483	277/7206	6.45435759418e-05
ko05168	Herpes simplex infection	1/483	182/7206	6.65641525177e-05
ko04972	Pancreatic secretion	19/483	111/7206	0.000125594012292
ko04072	Phospholipase D signaling pathway	28/483	197/7206	0.000126926242916
ko05164	Influenza A	1/483	167/7206	0.000219792638704
ko04260	Cardiac muscle contraction	17/483	98/7206	0.000239313774968
ko04971	Gastric acid secretion	17/483	98/7206	0.000239313774968
ko04010	MAPK signaling pathway	38/483	321/7206	0.000529627368896
ko04730	Long-term depression	14/483	78/7206	0.000585246638572
ko03040	Spliceosome	1/483	145/7206	0.00106485977583
ko04514	Cell adhesion molecules (CAMs)	19/483	130/7206	0.00110006906355
ko04966	Collecting duct acid secretion	7/483	26/7206	0.00124903464437
ko04022	cGMP-PKG signaling pathway	27/483	216/7206	0.00137169686399
ko04550	Signaling pathways regulating pluripotency of stem cells	2/483	165/7206	0.00140406316902
ko04924	Renin secretion	14/483	86/7206	0.00158383848563
ko04630	Jak-STAT signaling pathway	1/483	132/7206	0.00222273644269
ko05169	Epstein-Barr virus infection	4/483	206/7206	0.00268982220604
ko05110	Vibrio cholerae infection	11/483	63/7206	0.00279073581657
ko04621	NOD-like receptor signaling pathway	2/483	157/7206	0.0030356599124
ko04745	Phototransduction - fly	8/483	38/7206	0.0031393272046
ko04070	Phosphatidylinositol signaling system	16/483	112/7206	0.00346612012119
ko05205	Proteoglycans in cancer	7/483	271/7206	0.00398729384221
ko05162	Measles	1/483	120/7206	0.00473055095946
ko04668	TNF signaling pathway	1/483	120/7206	0.00473055095946
ko04750	Inflammatory mediator regulation of TRP channels	17/483	122/7206	0.00495985824061
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/483	79/7206	0.00596366228815
ko04540	Gap junction	17/483	128/7206	0.00631181666562
ko05215	Prostate cancer	1/483	111/7206	0.006672694466
ko05200	Pathways in cancer	19/483	492/7206	0.00667802938977
ko04915	Estrogen signaling pathway	17/483	131/7206	0.00740010690822
ko04210	Apoptosis	4/483	180/7206	0.00980450063765
ko04141	Protein processing in endoplasmic reticulum	4/483	184/7206	0.0100912642569
ko00512	Mucin type O-glycan biosynthesis	6/483	29/7206	0.011113299884
ko05414	Dilated cardiomyopathy	15/483	112/7206	0.0111336588857
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/483	14/7206	0.0116272983589
ko05161	Hepatitis B	4/483	173/7206	0.0134477524248
ko04014	Ras signaling pathway	29/483	279/7206	0.0193463562715
ko00513	Various types of N-glycan biosynthesis	7/483	42/7206	0.0202662888098
ko04740	Olfactory transduction	11/483	80/7206	0.020821425986
ko05211	Renal cell carcinoma	1/483	96/7206	0.0210723799126
ko05010	Alzheimer's disease	22/483	202/7206	0.0216324623995
ko05166	HTLV-I infection	10/483	292/7206	0.0222712949349
ko05410	Hypertrophic cardiomyopathy (HCM)	13/483	100/7206	0.0232601607315
ko05034	Alcoholism	25/483	238/7206	0.0240137440316
ko04120	Ubiquitin mediated proteolysis	3/483	138/7206	0.0250055890741
ko04140	Autophagy - animal	4/483	164/7206	0.0254012511961
ko00650	Butanoate metabolism	5/483	26/7206	0.0269756637755
ko04626	Plant-pathogen interaction	4/483	18/7206	0.0287382636709
ko04657	IL-17 signaling pathway	1/483	87/7206	0.0296097857757
ko05222	Small cell lung cancer	1/483	89/7206	0.0300614978661
ko04744	Phototransduction	6/483	36/7206	0.0307105718357
ko05120	Epithelial cell signaling in Helicobacter pylori infection	12/483	92/7206	0.0317388808618
ko00240	Pyrimidine metabolism	2/483	110/7206	0.0334171728713
ko04510	Focal adhesion	8/483	240/7206	0.0344637615655
ko04114	Oocyte meiosis	16/483	139/7206	0.0369693571965
ko05230	Central carbon metabolism in cancer	1/483	81/7206	0.0427685841573
ko04670	Leukocyte transendothelial migration	4/483	151/7206	0.0463582535819
ko05322	Systemic lupus erythematosus	4/483	151/7206	0.0463582535819