ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	66/828	152/7206	6.08713138955e-24
ko05033	Nicotine addiction	37/828	56/7206	4.05366027483e-22
ko04080	Neuroactive ligand-receptor interaction	118/828	423/7206	1.34062105366e-21
ko05032	Morphine addiction	50/828	110/7206	1.94052844118e-19
ko04713	Circadian entrainment	55/828	136/7206	2.20838060995e-18
ko04727	GABAergic synapse	46/828	110/7206	3.10200568066e-16
ko04728	Dopaminergic synapse	62/828	185/7206	7.48411386776e-16
ko04721	Synaptic vesicle cycle	37/828	80/7206	5.35044210678e-15
ko04725	Cholinergic synapse	55/828	160/7206	1.00736588982e-14
ko04024	cAMP signaling pathway	77/828	279/7206	4.03348224068e-14
ko04723	Retrograde endocannabinoid signaling	56/828	175/7206	1.85798259082e-13
ko04744	Phototransduction	21/828	36/7206	1.5006320142e-11
ko04911	Insulin secretion	40/828	117/7206	5.84864497812e-11
ko04261	Adrenergic signaling in cardiomyocytes	56/828	205/7206	2.27432089985e-10
ko04921	Oxytocin signaling pathway	56/828	209/7206	6.49688107562e-10
ko05031	Amphetamine addiction	31/828	91/7206	9.56981415144e-09
ko04020	Calcium signaling pathway	63/828	265/7206	9.99967092151e-09
ko04726	Serotonergic synapse	37/828	137/7206	4.13998633813e-07
ko05030	Cocaine addiction	24/828	73/7206	9.51204726854e-07
ko04022	cGMP-PKG signaling pathway	49/828	216/7206	2.05619305129e-06
ko04720	Long-term potentiation	28/828	99/7206	3.65468098352e-06
ko04010	MAPK signaling pathway	65/828	321/7206	3.74959799309e-06
ko04970	Salivary secretion	27/828	95/7206	4.91677857392e-06
ko03040	Spliceosome	2/828	145/7206	8.06305100666e-06
ko04514	Cell adhesion molecules (CAMs)	33/828	130/7206	8.87357770233e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	22/828	74/7206	1.68717167318e-05
ko05322	Systemic lupus erythematosus	3/828	151/7206	2.46454523818e-05
ko05203	Viral carcinogenesis	12/828	277/7206	3.08645414468e-05
ko03013	RNA transport	4/828	166/7206	3.34952991352e-05
ko04360	Axon guidance	48/828	233/7206	3.96929635474e-05
ko04742	Taste transduction	18/828	61/7206	0.000108742620888
ko04110	Cell cycle	4/828	145/7206	0.000191832634985
ko04924	Renin secretion	22/828	86/7206	0.000229973408969
ko04925	Aldosterone synthesis and secretion	25/828	105/7206	0.000299697241821
ko04971	Gastric acid secretion	24/828	98/7206	0.000301717566762
ko04120	Ubiquitin mediated proteolysis	4/828	138/7206	0.00038919771061
ko04972	Pancreatic secretion	26/828	111/7206	0.000406618878242
ko04072	Phospholipase D signaling pathway	39/828	197/7206	0.000590748529279
ko04260	Cardiac muscle contraction	23/828	98/7206	0.000651180797899
ko04710	Circadian rhythm	13/828	43/7206	0.000750412743953
ko04964	Proximal tubule bicarbonate reclamation	10/828	29/7206	0.00098164033808
ko04730	Long-term depression	19/828	78/7206	0.00110974382139
ko05164	Influenza A	7/828	167/7206	0.00128932266589
ko04966	Collecting duct acid secretion	9/828	26/7206	0.00170192981915
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/828	79/7206	0.00192436620379
ko04014	Ras signaling pathway	49/828	279/7206	0.00207754851226
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/828	14/7206	0.00300426805403
ko05168	Herpes simplex infection	9/828	182/7206	0.00305821022728
ko04141	Protein processing in endoplasmic reticulum	9/828	184/7206	0.00312048596839
ko04976	Bile secretion	18/828	80/7206	0.00420674718597
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/828	59/7206	0.00661910365184
ko04930	Type II diabetes mellitus	13/828	54/7206	0.00823115509297
ko04071	Sphingolipid signaling pathway	30/828	162/7206	0.00825988217186
ko04371	Apelin signaling pathway	32/828	177/7206	0.00828744711854
ko05205	Proteoglycans in cancer	18/828	271/7206	0.00858188029955
ko04745	Phototransduction - fly	10/828	38/7206	0.00889745534573
ko05140	Leishmaniasis	2/828	75/7206	0.0101237460982
ko05414	Dilated cardiomyopathy	22/828	112/7206	0.0104291333343
ko04060	Cytokine-cytokine receptor interaction	11/828	191/7206	0.0108271204206
ko04740	Olfactory transduction	17/828	80/7206	0.011933309371
ko05161	Hepatitis B	10/828	173/7206	0.0152054603243
ko04540	Gap junction	24/828	128/7206	0.016269004299
ko00480	Glutathione metabolism	1/828	55/7206	0.0178022327783
ko04915	Estrogen signaling pathway	24/828	131/7206	0.0182138361345
ko04070	Phosphatidylinositol signaling system	21/828	112/7206	0.0235950260235
ko04973	Carbohydrate digestion and absorption	10/828	42/7206	0.0240179520469
ko04922	Glucagon signaling pathway	23/828	128/7206	0.0251081828262
ko05410	Hypertrophic cardiomyopathy (HCM)	19/828	100/7206	0.0256226375109
ko05110	Vibrio cholerae infection	13/828	63/7206	0.0288677892389
ko04750	Inflammatory mediator regulation of TRP channels	22/828	122/7206	0.0304757042985
ko04666	Fc gamma R-mediated phagocytosis	22/828	122/7206	0.0304757042985
ko04612	Antigen processing and presentation	3/828	77/7206	0.0306049101809
ko04610	Complement and coagulation cascades	3/828	79/7206	0.0311649315946
ko05169	Epstein-Barr virus infection	14/828	206/7206	0.0343328766523
ko05219	Bladder cancer	1/828	48/7206	0.0383316589801
ko05133	Pertussis	4/828	87/7206	0.041331333884
ko01212	Fatty acid metabolism	2/828	60/7206	0.0419140231081
ko04978	Mineral absorption	9/828	40/7206	0.0419207558792
ko00330	Arginine and proline metabolism	2/828	61/7206	0.0420620179433
ko04146	Peroxisome	4/828	89/7206	0.0423679071574
ko04115	p53 signaling pathway	3/828	74/7206	0.0425744217054
ko04960	Aldosterone-regulated sodium reabsorption	9/828	41/7206	0.0464202311988
ko00240	Pyrimidine metabolism	6/828	110/7206	0.0486760642892
ko05166	HTLV-I infection	23/828	292/7206	0.0488807927698
ko05215	Prostate cancer	6/828	111/7206	0.049243660473