ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 11/388 30/7206 2.06940190145e-07 ko04380 Osteoclast differentiation 22/388 134/7206 2.2712972172e-06 ko04060 Cytokine-cytokine receptor interaction 27/388 191/7206 3.28797232494e-06 ko05145 Toxoplasmosis 20/388 126/7206 1.11333968235e-05 ko05164 Influenza A 23/388 167/7206 2.72747275986e-05 ko05321 Inflammatory bowel disease (IBD) 12/388 56/7206 3.23076833305e-05 ko05162 Measles 18/388 120/7206 6.63508485231e-05 ko04710 Circadian rhythm 10/388 43/7206 7.05462604497e-05 ko04659 Th17 cell differentiation 16/388 106/7206 0.000155616159021 ko05140 Leishmaniasis 13/388 75/7206 0.000156547596466 ko04650 Natural killer cell mediated cytotoxicity 15/388 97/7206 0.000189047459756 ko04610 Complement and coagulation cascades 13/388 79/7206 0.000268277235963 ko04658 Th1 and Th2 cell differentiation 14/388 96/7206 0.000570055261467 ko04630 Jak-STAT signaling pathway 17/388 132/7206 0.000673965878961 ko00140 Steroid hormone biosynthesis 8/388 41/7206 0.0013086609903 ko05330 Allograft rejection 6/388 24/7206 0.00137713102947 ko05152 Tuberculosis 21/388 187/7206 0.00137910681829 ko00590 Arachidonic acid metabolism 9/388 52/7206 0.00161932466831 ko04064 NF-kappa B signaling pathway 13/388 96/7206 0.00178854575408 ko04621 NOD-like receptor signaling pathway 18/388 157/7206 0.00201139477958 ko05168 Herpes simplex infection 20/388 182/7206 0.00221467262507 ko03013 RNA transport 1/388 166/7206 0.00240980322728 ko05150 Staphylococcus aureus infection 7/388 36/7206 0.00266742963426 ko00592 alpha-Linolenic acid metabolism 5/388 19/7206 0.00273669399724 ko04672 Intestinal immune network for IgA production 7/388 37/7206 0.00314080645564 ko00120 Primary bile acid biosynthesis 5/388 20/7206 0.00349012555148 ko04660 T cell receptor signaling pathway 15/388 124/7206 0.00356802380782 ko04217 Necroptosis 19/388 178/7206 0.0037363500042 ko05320 Autoimmune thyroid disease 6/388 29/7206 0.00386888479844 ko04611 Platelet activation 18/388 163/7206 0.0039627087541 ko04137 Mitophagy - animal 11/388 82/7206 0.0042467927468 ko03040 Spliceosome 1/388 145/7206 0.00477316924322 ko04110 Cell cycle 1/388 145/7206 0.00477316924322 ko05167 Kaposi's sarcoma-associated herpesvirus infection 20/388 191/7206 0.00480624952714 ko05034 Alcoholism 4/388 238/7206 0.00766404218571 ko04612 Antigen processing and presentation 10/388 77/7206 0.00789815391792 ko05144 Malaria 7/388 45/7206 0.00956920409059 ko05160 Hepatitis C 16/388 153/7206 0.00988711902554 ko05310 Asthma 4/388 17/7206 0.011255786879 ko05332 Graft-versus-host disease 4/388 18/7206 0.0138693267695 ko03010 Ribosome 1/388 129/7206 0.0155764850104 ko04145 Phagosome 16/388 162/7206 0.019742486755 ko00051 Fructose and mannose metabolism 6/388 42/7206 0.023758971382 ko04930 Type II diabetes mellitus 7/388 54/7206 0.0247364178685 ko05224 Breast cancer 3/388 174/7206 0.0257742511651 ko04514 Cell adhesion molecules (CAMs) 13/388 130/7206 0.0283586474069 ko04711 Circadian rhythm - fly 3/388 13/7206 0.0295904124663 ko04664 Fc epsilon RI signaling pathway 9/388 77/7206 0.0356086920125 ko00220 Arginine biosynthesis 4/388 24/7206 0.0373882684158 ko05161 Hepatitis B 16/388 173/7206 0.0378172739847 ko04666 Fc gamma R-mediated phagocytosis 12/388 122/7206 0.0397329501237 ko05230 Central carbon metabolism in cancer 9/388 81/7206 0.0403091632595 ko01040 Biosynthesis of unsaturated fatty acids 4/388 25/7206 0.0426843264025 ko04350 TGF-beta signaling pathway 1/388 103/7206 0.044463840456