ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 29/203 167/7206 1.30379780167e-15 ko04621 NOD-like receptor signaling pathway 26/203 157/7206 1.40621010854e-13 ko04060 Cytokine-cytokine receptor interaction 28/203 191/7206 3.54421170726e-13 ko04217 Necroptosis 26/203 178/7206 2.89547758423e-12 ko05168 Herpes simplex infection 26/203 182/7206 4.89289148499e-12 ko05162 Measles 21/203 120/7206 1.21315674886e-11 ko05340 Primary immunodeficiency 11/203 30/7206 2.31492359669e-10 ko05145 Toxoplasmosis 20/203 126/7206 2.41268008819e-10 ko04612 Antigen processing and presentation 15/203 77/7206 2.5233861867e-09 ko04659 Th17 cell differentiation 17/203 106/7206 4.87470199067e-09 ko04380 Osteoclast differentiation 19/203 134/7206 4.93258047587e-09 ko04622 RIG-I-like receptor signaling pathway 13/203 62/7206 1.18262287209e-08 ko05140 Leishmaniasis 14/203 75/7206 1.56379186297e-08 ko05321 Inflammatory bowel disease (IBD) 12/203 56/7206 3.39418943609e-08 ko05152 Tuberculosis 21/203 187/7206 5.14586333274e-08 ko05320 Autoimmune thyroid disease 9/203 29/7206 5.75272232153e-08 ko04658 Th1 and Th2 cell differentiation 15/203 96/7206 5.83517929773e-08 ko04620 Toll-like receptor signaling pathway 15/203 100/7206 1.02310900374e-07 ko04630 Jak-STAT signaling pathway 17/203 132/7206 1.40669633453e-07 ko05330 Allograft rejection 8/203 24/7206 1.72536290672e-07 ko05161 Hepatitis B 19/203 173/7206 3.28720253691e-07 ko04064 NF-kappa B signaling pathway 14/203 96/7206 3.96160187758e-07 ko05150 Staphylococcus aureus infection 9/203 36/7206 4.55605414533e-07 ko04672 Intestinal immune network for IgA production 9/203 37/7206 5.87499272557e-07 ko05133 Pertussis 13/203 87/7206 7.83302620883e-07 ko04623 Cytosolic DNA-sensing pathway 9/203 41/7206 1.50032199999e-06 ko04650 Natural killer cell mediated cytotoxicity 13/203 97/7206 2.78435578585e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/203 191/7206 6.29369771501e-06 ko05332 Graft-versus-host disease 6/203 18/7206 6.49516214572e-06 ko04660 T cell receptor signaling pathway 14/203 124/7206 8.98567491693e-06 ko04145 Phagosome 16/203 162/7206 1.16089202329e-05 ko05160 Hepatitis C 15/203 153/7206 2.39979062174e-05 ko04668 TNF signaling pathway 13/203 120/7206 2.95924921375e-05 ko05323 Rheumatoid arthritis 11/203 89/7206 3.60686912856e-05 ko04640 Hematopoietic cell lineage 9/203 64/7206 6.72893980987e-05 ko05142 Chagas disease (American trypanosomiasis) 13/203 130/7206 6.90019533004e-05 ko05310 Asthma 5/203 17/7206 7.92835838425e-05 ko05416 Viral myocarditis 8/203 55/7206 0.000134826910586 ko04062 Chemokine signaling pathway 16/203 201/7206 0.000161782406127 ko00120 Primary bile acid biosynthesis 5/203 20/7206 0.0001853972951 ko04940 Type I diabetes mellitus 6/203 32/7206 0.000228000221059 ko04210 Apoptosis 14/203 180/7206 0.000527568116011 ko03050 Proteasome 7/203 54/7206 0.00073096207963 ko04662 B cell receptor signaling pathway 9/203 88/7206 0.000779344767129 ko05144 Malaria 6/203 45/7206 0.0015116428617 ko05166 HTLV-I infection 18/203 292/7206 0.00162080221194 ko04080 Neuroactive ligand-receptor interaction 3/203 423/7206 0.0035239439266 ko04514 Cell adhesion molecules (CAMs) 10/203 130/7206 0.00355840778174 ko04610 Complement and coagulation cascades 7/203 79/7206 0.00662475613735 ko00590 Arachidonic acid metabolism 5/203 52/7206 0.0150103004214 ko05034 Alcoholism 1/203 238/7206 0.0152213703257 ko01524 Platinum drug resistance 6/203 76/7206 0.0197998560833 ko05146 Amoebiasis 7/203 99/7206 0.0212998361949 ko05020 Prion diseases 4/203 40/7206 0.025325268323 ko00140 Steroid hormone biosynthesis 4/203 41/7206 0.0274633152292 ko05131 Shigellosis 6/203 82/7206 0.0276426029506 ko04020 Calcium signaling pathway 2/203 265/7206 0.0353369353804 ko04657 IL-17 signaling pathway 6/203 87/7206 0.0355662239925 ko04670 Leukocyte transendothelial migration 9/203 151/7206 0.0392579004333 ko04215 Apoptosis - multiple species 4/203 47/7206 0.042510307235 ko05169 Epstein-Barr virus infection 11/203 206/7206 0.0489971250845