ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	104/545	423/7206	1.84523934153e-29
ko05033	Nicotine addiction	37/545	56/7206	1.11396746334e-28
ko04724	Glutamatergic synapse	54/545	152/7206	1.41298104095e-23
ko04727	GABAergic synapse	38/545	110/7206	2.06724120059e-16
ko05032	Morphine addiction	35/545	110/7206	5.72602460962e-14
ko04728	Dopaminergic synapse	46/545	185/7206	1.70183715817e-13
ko05030	Cocaine addiction	27/545	73/7206	7.81282303537e-13
ko04721	Synaptic vesicle cycle	28/545	80/7206	1.42768229268e-12
ko04723	Retrograde endocannabinoid signaling	43/545	175/7206	1.69147134046e-12
ko04713	Circadian entrainment	36/545	136/7206	1.15025284286e-11
ko04024	cAMP signaling pathway	52/545	279/7206	7.56633265798e-10
ko05031	Amphetamine addiction	26/545	91/7206	1.49240829688e-09
ko04514	Cell adhesion molecules (CAMs)	30/545	130/7206	2.08136342672e-08
ko04020	Calcium signaling pathway	47/545	265/7206	3.4862969436e-08
ko04261	Adrenergic signaling in cardiomyocytes	39/545	205/7206	5.05344499406e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	21/545	74/7206	6.56448796757e-08
ko04010	MAPK signaling pathway	52/545	321/7206	1.05734971918e-07
ko04911	Insulin secretion	27/545	117/7206	1.07178819161e-07
ko04921	Oxytocin signaling pathway	38/545	209/7206	3.14881761294e-07
ko04725	Cholinergic synapse	31/545	160/7206	8.13966591008e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/545	79/7206	1.02634752381e-06
ko04720	Long-term potentiation	22/545	99/7206	3.20468570333e-06
ko04742	Taste transduction	16/545	61/7206	7.5804599846e-06
ko05414	Dilated cardiomyopathy	23/545	112/7206	7.92799995996e-06
ko05203	Viral carcinogenesis	5/545	277/7206	3.66177869725e-05
ko04260	Cardiac muscle contraction	19/545	98/7206	0.00011030918163
ko05410	Hypertrophic cardiomyopathy (HCM)	19/545	100/7206	0.000146119678643
ko04730	Long-term depression	16/545	78/7206	0.000192268905563
ko03040	Spliceosome	1/545	145/7206	0.000204573481431
ko04970	Salivary secretion	17/545	95/7206	0.000668981989006
ko04726	Serotonergic synapse	22/545	137/7206	0.000794092601867
ko04360	Axon guidance	32/545	233/7206	0.000902485546092
ko04072	Phospholipase D signaling pathway	28/545	197/7206	0.00094993467919
ko01200	Carbon metabolism	1/545	128/7206	0.00100695190239
ko04915	Estrogen signaling pathway	21/545	131/7206	0.00112335858651
ko03013	RNA transport	3/545	166/7206	0.00165777512222
ko04060	Cytokine-cytokine receptor interaction	4/545	191/7206	0.00194096984253
ko00515	Mannose type O-glycan biosynthesis	7/545	25/7206	0.00196583671654
ko05205	Proteoglycans in cancer	8/545	271/7206	0.00209071813637
ko05168	Herpes simplex infection	4/545	182/7206	0.00260713645684
ko04141	Protein processing in endoplasmic reticulum	4/545	184/7206	0.00264476296361
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/545	14/7206	0.00273710370798
ko05169	Epstein-Barr virus infection	5/545	206/7206	0.00286551152266
ko04120	Ubiquitin mediated proteolysis	2/545	138/7206	0.00286812943289
ko00240	Pyrimidine metabolism	1/545	110/7206	0.0030516644674
ko04540	Gap junction	19/545	128/7206	0.00376551020064
ko05322	Systemic lupus erythematosus	3/545	151/7206	0.00465679854624
ko04972	Pancreatic secretion	17/545	111/7206	0.00538504039962
ko04022	cGMP-PKG signaling pathway	28/545	216/7206	0.00548560470577
ko00190	Oxidative phosphorylation	2/545	127/7206	0.00584274287679
ko04930	Type II diabetes mellitus	10/545	54/7206	0.00649572561634
ko04110	Cell cycle	3/545	145/7206	0.00652333927681
ko05164	Influenza A	4/545	167/7206	0.00701707105339
ko04925	Aldosterone synthesis and secretion	16/545	105/7206	0.00758778946138
ko05162	Measles	2/545	120/7206	0.00818280936488
ko04621	NOD-like receptor signaling pathway	4/545	157/7206	0.0134362738125
ko04217	Necroptosis	5/545	178/7206	0.013538657442
ko04015	Rap1 signaling pathway	32/545	278/7206	0.0148445516496
ko05215	Prostate cancer	2/545	111/7206	0.0168353809739
ko04630	Jak-STAT signaling pathway	3/545	132/7206	0.0182661244982
ko04142	Lysosome	4/545	151/7206	0.0182935932821
ko03018	RNA degradation	1/545	84/7206	0.0202327648844
ko01230	Biosynthesis of amino acids	1/545	85/7206	0.020549418801
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/545	182/7206	0.0227000925657
ko04150	mTOR signaling pathway	6/545	184/7206	0.0228336518664
ko04350	TGF-beta signaling pathway	2/545	103/7206	0.0232513116038
ko04140	Autophagy - animal	5/545	164/7206	0.0239673630675
ko04014	Ras signaling pathway	31/545	279/7206	0.0277097781088
ko03008	Ribosome biogenesis in eukaryotes	1/545	79/7206	0.0294764241819
ko04924	Renin secretion	12/545	86/7206	0.0365781156472
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/545	59/7206	0.041311388673
ko00310	Lysine degradation	1/545	73/7206	0.0423217281463
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/545	26/7206	0.0424233215281
ko00010	Glycolysis / Gluconeogenesis	1/545	74/7206	0.0428763378022
ko04510	Focal adhesion	10/545	240/7206	0.0458164098138
ko04064	NF-kappa B signaling pathway	2/545	96/7206	0.0480956873335
ko05152	Tuberculosis	7/545	187/7206	0.0483194160393