ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	13/189	56/7206	1.29588392908e-09
ko04727	GABAergic synapse	15/189	110/7206	1.45336577077e-07
ko04723	Retrograde endocannabinoid signaling	16/189	175/7206	1.25425979196e-05
ko04080	Neuroactive ligand-receptor interaction	27/189	423/7206	1.34184529536e-05
ko04728	Dopaminergic synapse	16/189	185/7206	2.52145586444e-05
ko05032	Morphine addiction	12/189	110/7206	2.78007346297e-05
ko04724	Glutamatergic synapse	14/189	152/7206	4.1070341814e-05
ko04713	Circadian entrainment	12/189	136/7206	0.000221179017574
ko04721	Synaptic vesicle cycle	9/189	80/7206	0.000225737124386
ko00430	Taurine and hypotaurine metabolism	4/189	14/7206	0.000373363945836
ko04978	Mineral absorption	6/189	40/7206	0.000549031707804
ko05030	Cocaine addiction	8/189	73/7206	0.000603729753989
ko04725	Cholinergic synapse	12/189	160/7206	0.000970935657858
ko04744	Phototransduction	5/189	36/7206	0.00229182817679
ko00250	Alanine, aspartate and glutamate metabolism	5/189	38/7206	0.00292507375356
ko04726	Serotonergic synapse	10/189	137/7206	0.00311227387918
ko04742	Taste transduction	6/189	61/7206	0.00504166939824
ko04950	Maturity onset diabetes of the young	4/189	29/7206	0.00651579966497
ko05166	HTLV-I infection	1/189	292/7206	0.00742929653951
ko05031	Amphetamine addiction	7/189	91/7206	0.00967507734143
ko05203	Viral carcinogenesis	1/189	277/7206	0.0108143627194
ko04976	Bile secretion	6/189	80/7206	0.0181592563796
ko00140	Steroid hormone biosynthesis	4/189	41/7206	0.0217927155546
ko00830	Retinol metabolism	4/189	42/7206	0.0236071116764
ko00460	Cyanoamino acid metabolism	2/189	11/7206	0.0322110673698
ko04911	Insulin secretion	7/189	117/7206	0.0337557436377
ko04964	Proximal tubule bicarbonate reclamation	3/189	29/7206	0.0393553195799
ko05014	Amyotrophic lateral sclerosis (ALS)	5/189	74/7206	0.0442718472571
ko05169	Epstein-Barr virus infection	1/189	206/7206	0.0453270292352
ko05016	Huntington's disease	1/189	215/7206	0.0466949562964