ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 24/262 167/7206 6.0165108241e-09 ko04621 NOD-like receptor signaling pathway 22/262 157/7206 4.26604866937e-08 ko04060 Cytokine-cytokine receptor interaction 24/262 191/7206 8.65672224873e-08 ko04380 Osteoclast differentiation 19/262 134/7206 3.05943839467e-07 ko05321 Inflammatory bowel disease (IBD) 11/262 56/7206 4.14020295676e-06 ko05162 Measles 16/262 120/7206 6.1333917032e-06 ko04064 NF-kappa B signaling pathway 14/262 96/7206 8.24507165175e-06 ko05160 Hepatitis C 18/262 153/7206 9.71524039136e-06 ko05145 Toxoplasmosis 15/262 126/7206 4.72620391052e-05 ko05161 Hepatitis B 18/262 173/7206 5.21918692809e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/262 191/7206 6.00960612682e-05 ko04620 Toll-like receptor signaling pathway 13/262 100/7206 6.05492743682e-05 ko05140 Leishmaniasis 11/262 75/7206 7.37881902202e-05 ko04217 Necroptosis 18/262 178/7206 7.60031942715e-05 ko04668 TNF signaling pathway 14/262 120/7206 0.000105604666975 ko04658 Th1 and Th2 cell differentiation 12/262 96/7206 0.000170336750158 ko05168 Herpes simplex infection 17/262 182/7206 0.000315080267912 ko04662 B cell receptor signaling pathway 11/262 88/7206 0.000317405348042 ko05152 Tuberculosis 17/262 187/7206 0.000433366966557 ko04610 Complement and coagulation cascades 10/262 79/7206 0.000535072703362 ko04650 Natural killer cell mediated cytotoxicity 11/262 97/7206 0.000739034295197 ko04710 Circadian rhythm 7/262 43/7206 0.000812902008136 ko04630 Jak-STAT signaling pathway 13/262 132/7206 0.000973472046486 ko05323 Rheumatoid arthritis 10/262 89/7206 0.00137338644106 ko04659 Th17 cell differentiation 11/262 106/7206 0.00154836966569 ko04622 RIG-I-like receptor signaling pathway 8/262 62/7206 0.00168991213963 ko05150 Staphylococcus aureus infection 6/262 36/7206 0.00169517922905 ko04672 Intestinal immune network for IgA production 6/262 37/7206 0.00196272325268 ko00590 Arachidonic acid metabolism 7/262 52/7206 0.00255536202022 ko04623 Cytosolic DNA-sensing pathway 6/262 41/7206 0.00336237485306 ko04933 AGE-RAGE signaling pathway in diabetic complications 12/262 135/7206 0.00359566316366 ko00051 Fructose and mannose metabolism 6/262 42/7206 0.00380577219866 ko05340 Primary immunodeficiency 5/262 30/7206 0.00413235609873 ko05133 Pertussis 9/262 87/7206 0.00416066376498 ko04660 T cell receptor signaling pathway 11/262 124/7206 0.005303954498 ko05144 Malaria 6/262 45/7206 0.00539676341589 ko05215 Prostate cancer 10/262 111/7206 0.00693073838316 ko05142 Chagas disease (American trypanosomiasis) 11/262 130/7206 0.00753172626656 ko04611 Platelet activation 13/262 163/7206 0.00850102242899 ko02010 ABC transporters 5/262 39/7206 0.0128092651397 ko04917 Prolactin signaling pathway 8/262 87/7206 0.0134273732354 ko04657 IL-17 signaling pathway 8/262 87/7206 0.0134273732354 ko04210 Apoptosis 13/262 180/7206 0.0150276176101 ko00140 Steroid hormone biosynthesis 5/262 41/7206 0.0157240168041 ko04115 p53 signaling pathway 7/262 74/7206 0.0175203156388 ko05134 Legionellosis 7/262 74/7206 0.0175203156388 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/262 92/7206 0.0183318873644 ko04062 Chemokine signaling pathway 14/262 201/7206 0.0192162191768 ko05166 HTLV-I infection 18/262 292/7206 0.0247200967952 ko05132 Salmonella infection 8/262 98/7206 0.0257707040833 ko05230 Central carbon metabolism in cancer 7/262 81/7206 0.0273740811079 ko05131 Shigellosis 7/262 82/7206 0.0290367535528 ko00592 alpha-Linolenic acid metabolism 3/262 19/7206 0.0299201026725 ko04066 HIF-1 signaling pathway 9/262 123/7206 0.044836415709 ko04724 Glutamatergic synapse 1/262 152/7206 0.0455353308417