ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	127/762	423/7206	2.38566060438e-30
ko04724	Glutamatergic synapse	67/762	152/7206	6.69151063377e-27
ko05033	Nicotine addiction	37/762	56/7206	2.10994830779e-23
ko04727	GABAergic synapse	49/762	110/7206	3.60523839296e-20
ko05032	Morphine addiction	49/762	110/7206	3.60523839296e-20
ko04721	Synaptic vesicle cycle	39/762	80/7206	5.44491724379e-18
ko04713	Circadian entrainment	51/762	136/7206	4.934147471e-17
ko04728	Dopaminergic synapse	61/762	185/7206	5.57896490008e-17
ko04723	Retrograde endocannabinoid signaling	58/762	175/7206	2.59800405582e-16
ko04024	cAMP signaling pathway	73/762	279/7206	6.39741190528e-14
ko04020	Calcium signaling pathway	66/762	265/7206	1.25474761608e-11
ko04911	Insulin secretion	39/762	117/7206	1.91037864134e-11
ko04725	Cholinergic synapse	47/762	160/7206	2.59707475451e-11
ko04744	Phototransduction	20/762	36/7206	3.40922630007e-11
ko04742	Taste transduction	24/762	61/7206	3.52431710511e-09
ko04726	Serotonergic synapse	39/762	137/7206	3.62138860543e-09
ko05031	Amphetamine addiction	30/762	91/7206	5.63703920592e-09
ko04921	Oxytocin signaling pathway	51/762	209/7206	6.67424465631e-09
ko04261	Adrenergic signaling in cardiomyocytes	50/762	205/7206	9.78672974663e-09
ko04720	Long-term potentiation	31/762	99/7206	1.26550309338e-08
ko05203	Viral carcinogenesis	6/762	277/7206	7.66994429334e-08
ko05030	Cocaine addiction	24/762	73/7206	2.02841787609e-07
ko04970	Salivary secretion	27/762	95/7206	9.78220428146e-07
ko04060	Cytokine-cytokine receptor interaction	3/762	191/7206	1.89313894027e-06
ko04925	Aldosterone synthesis and secretion	28/762	105/7206	2.50808931002e-06
ko05164	Influenza A	2/762	167/7206	2.5723040726e-06
ko05169	Epstein-Barr virus infection	4/762	206/7206	2.64850071932e-06
ko03040	Spliceosome	1/762	145/7206	3.27361901086e-06
ko05168	Herpes simplex infection	3/762	182/7206	3.96448884771e-06
ko04966	Collecting duct acid secretion	11/762	26/7206	2.98316742358e-05
ko04972	Pancreatic secretion	26/762	111/7206	7.0880233102e-05
ko04022	cGMP-PKG signaling pathway	42/762	216/7206	7.13947077101e-05
ko05322	Systemic lupus erythematosus	3/762	151/7206	7.95070565982e-05
ko04010	MAPK signaling pathway	57/762	321/7206	8.15243525848e-05
ko04072	Phospholipase D signaling pathway	39/762	197/7206	8.73666039801e-05
ko03013	RNA transport	4/762	166/7206	0.000100320591685
ko04730	Long-term depression	20/762	78/7206	0.000123008095154
ko04110	Cell cycle	3/762	145/7206	0.00017074152442
ko05110	Vibrio cholerae infection	17/762	63/7206	0.000201142059728
ko04070	Phosphatidylinositol signaling system	25/762	112/7206	0.00025707785478
ko05162	Measles	2/762	120/7206	0.000260615800487
ko04745	Phototransduction - fly	12/762	38/7206	0.000359800402193
ko05166	HTLV-I infection	14/762	292/7206	0.000441252065436
ko04740	Olfactory transduction	19/762	80/7206	0.000644731759751
ko04260	Cardiac muscle contraction	22/762	98/7206	0.000660716337745
ko04971	Gastric acid secretion	22/762	98/7206	0.000660716337745
ko05014	Amyotrophic lateral sclerosis (ALS)	18/762	74/7206	0.000777809779285
ko05205	Proteoglycans in cancer	13/762	271/7206	0.00082198817615
ko05215	Prostate cancer	2/762	111/7206	0.000839455193117
ko05161	Hepatitis B	6/762	173/7206	0.000979995211029
ko04510	Focal adhesion	11/762	240/7206	0.0012329993943
ko04514	Cell adhesion molecules (CAMs)	26/762	130/7206	0.00127923384468
ko04668	TNF signaling pathway	3/762	120/7206	0.0014442017623
ko04210	Apoptosis	7/762	180/7206	0.00189995749074
ko04610	Complement and coagulation cascades	1/762	79/7206	0.00267075273451
ko03008	Ribosome biogenesis in eukaryotes	1/762	79/7206	0.00267075273451
ko04141	Protein processing in endoplasmic reticulum	8/762	184/7206	0.00331580540448
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/762	92/7206	0.00342422149537
ko04621	NOD-like receptor signaling pathway	6/762	157/7206	0.00349600751635
ko04064	NF-kappa B signaling pathway	2/762	96/7206	0.0037305407458
ko05140	Leishmaniasis	1/762	75/7206	0.00392938303575
ko04924	Renin secretion	18/762	86/7206	0.00403487532865
ko04550	Signaling pathways regulating pluripotency of stem cells	7/762	165/7206	0.0045946156841
ko05200	Pathways in cancer	34/762	492/7206	0.00488345014438
ko05222	Small cell lung cancer	2/762	89/7206	0.0050849139071
ko04630	Jak-STAT signaling pathway	5/762	132/7206	0.00639864096458
ko04657	IL-17 signaling pathway	2/762	87/7206	0.00744925348493
ko04964	Proximal tubule bicarbonate reclamation	8/762	29/7206	0.00857621212688
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/762	79/7206	0.00906469322487
ko04014	Ras signaling pathway	43/762	279/7206	0.0097193607554
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/762	182/7206	0.00987468293461
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/762	14/7206	0.0115728792111
ko04120	Ubiquitin mediated proteolysis	6/762	138/7206	0.0116535981096
ko04330	Notch signaling pathway	1/762	62/7206	0.0124575781561
ko04540	Gap junction	23/762	128/7206	0.0125522612836
ko00562	Inositol phosphate metabolism	17/762	89/7206	0.013995022099
ko04612	Antigen processing and presentation	2/762	77/7206	0.0149681251762
ko00310	Lysine degradation	2/762	73/7206	0.0213336759784
ko01524	Platinum drug resistance	2/762	76/7206	0.0220795362063
ko04350	TGF-beta signaling pathway	4/762	103/7206	0.0227628084264
ko05034	Alcoholism	36/762	238/7206	0.0242052048544
ko04810	Regulation of actin cytoskeleton	17/762	264/7206	0.0245086576706
ko00520	Amino sugar and nucleotide sugar metabolism	1/762	55/7206	0.0266678873047
ko00480	Glutathione metabolism	1/762	55/7206	0.0266678873047
ko00512	Mucin type O-glycan biosynthesis	7/762	29/7206	0.0281749217422
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/762	59/7206	0.0294895458015
ko04915	Estrogen signaling pathway	22/762	131/7206	0.0298687145888
ko03320	PPAR signaling pathway	2/762	69/7206	0.030308698389
ko04214	Apoptosis - fly	2/762	72/7206	0.0312834269099
ko05224	Breast cancer	10/762	174/7206	0.0335681681784
ko05206	MicroRNAs in cancer	10/762	177/7206	0.034185909187
ko04626	Plant-pathogen interaction	5/762	18/7206	0.0347255325098
ko00513	Various types of N-glycan biosynthesis	9/762	42/7206	0.0377614212131
ko00240	Pyrimidine metabolism	5/762	110/7206	0.0404797657001
ko05418	Fluid shear stress and atherosclerosis	10/762	173/7206	0.043873976412
ko05217	Basal cell carcinoma	2/762	68/7206	0.0441868873464
ko05010	Alzheimer's disease	30/762	202/7206	0.0486570952517