ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 13/116 157/7206 1.20176373817e-06 ko04064 NF-kappa B signaling pathway 10/116 96/7206 2.79069748939e-06 ko04217 Necroptosis 12/116 178/7206 2.61768199815e-05 ko04660 T cell receptor signaling pathway 10/116 124/7206 2.76776350662e-05 ko04380 Osteoclast differentiation 10/116 134/7206 5.40512404338e-05 ko05161 Hepatitis B 11/116 173/7206 9.82982869968e-05 ko05162 Measles 9/116 120/7206 0.000124657890249 ko04668 TNF signaling pathway 9/116 120/7206 0.000124657890249 ko04658 Th1 and Th2 cell differentiation 8/116 96/7206 0.00014432333392 ko04620 Toll-like receptor signaling pathway 8/116 100/7206 0.00019200894646 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/116 191/7206 0.000236281426982 ko04659 Th17 cell differentiation 8/116 106/7206 0.000287237968698 ko05212 Pancreatic cancer 7/116 83/7206 0.000353410224794 ko05418 Fluid shear stress and atherosclerosis 10/116 173/7206 0.000445085919684 ko04662 B cell receptor signaling pathway 7/116 88/7206 0.000505814070452 ko00511 Other glycan degradation 4/116 26/7206 0.000724910217331 ko05164 Influenza A 9/116 167/7206 0.00141962683225 ko04015 Rap1 signaling pathway 12/116 278/7206 0.00163933114781 ko05321 Inflammatory bowel disease (IBD) 5/116 56/7206 0.00196851893098 ko05215 Prostate cancer 7/116 111/7206 0.00199805618426 ko05200 Pathways in cancer 17/116 492/7206 0.00237934924602 ko04210 Apoptosis 9/116 180/7206 0.00238047253944 ko05221 Acute myeloid leukemia 5/116 63/7206 0.00331350306881 ko04623 Cytosolic DNA-sensing pathway 4/116 41/7206 0.0040794664186 ko00531 Glycosaminoglycan degradation 3/116 23/7206 0.00569193075881 ko01521 EGFR tyrosine kinase inhibitor resistance 6/116 106/7206 0.0070656710436 ko05166 HTLV-I infection 11/116 292/7206 0.00715693694909 ko04218 Cellular senescence 8/116 177/7206 0.00754712096497 ko04070 Phosphatidylinositol signaling system 6/116 112/7206 0.00917064182527 ko00590 Arachidonic acid metabolism 4/116 52/7206 0.00952731861063 ko04151 PI3K-Akt signaling pathway 13/116 390/7206 0.0111142873908 ko05160 Hepatitis C 7/116 153/7206 0.0114895331641 ko04060 Cytokine-cytokine receptor interaction 8/116 191/7206 0.0116712016336 ko05220 Chronic myeloid leukemia 5/116 85/7206 0.0117026973786 ko04657 IL-17 signaling pathway 5/116 87/7206 0.0128543676553 ko00562 Inositol phosphate metabolism 5/116 89/7206 0.0140805631721 ko05222 Small cell lung cancer 5/116 89/7206 0.0140805631721 ko04014 Ras signaling pathway 10/116 279/7206 0.0141444734502 ko05145 Toxoplasmosis 6/116 126/7206 0.0157657316324 ko04611 Platelet activation 7/116 163/7206 0.0158439536441 ko00944 Flavone and flavonol biosynthesis 1/116 1/7206 0.0160976963641 ko04622 RIG-I-like receptor signaling pathway 4/116 62/7206 0.0173737341136 ko05169 Epstein-Barr virus infection 8/116 206/7206 0.0177286672338 ko00600 Sphingolipid metabolism 4/116 63/7206 0.0183269701167 ko04630 Jak-STAT signaling pathway 6/116 132/7206 0.019404483793 ko05132 Salmonella infection 5/116 98/7206 0.0205719851534 ko05223 Non-small cell lung cancer 4/116 66/7206 0.0213795696271 ko00564 Glycerophospholipid metabolism 5/116 99/7206 0.0213959875119 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/116 135/7206 0.021423221576 ko04931 Insulin resistance 6/116 137/7206 0.0228455517842 ko05168 Herpes simplex infection 7/116 182/7206 0.0271458168332 ko00565 Ether lipid metabolism 3/116 42/7206 0.0296053251436 ko05140 Leishmaniasis 4/116 75/7206 0.0323262595952 ko04142 Lysosome 6/116 151/7206 0.0346063296797 ko04370 VEGF signaling pathway 4/116 77/7206 0.0351317668806 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4/116 79/7206 0.0380746663017 ko04610 Complement and coagulation cascades 4/116 79/7206 0.0380746663017 ko04072 Phospholipase D signaling pathway 7/116 197/7206 0.0392612412698 ko04624 Toll and Imd signaling pathway 3/116 49/7206 0.0438478035634 ko05203 Viral carcinogenesis 9/116 277/7206 0.0442970762353 ko04066 HIF-1 signaling pathway 5/116 123/7206 0.0478971781628