ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 37/376 79/7206 3.94140498161e-27 ko04974 Protein digestion and absorption 25/376 96/7206 9.77161521589e-12 ko04975 Fat digestion and absorption 14/376 35/7206 7.43178616715e-10 ko04978 Mineral absorption 14/376 40/7206 5.84796124308e-09 ko04977 Vitamin digestion and absorption 10/376 22/7206 4.89300924693e-08 ko04976 Bile secretion 18/376 80/7206 9.87388224606e-08 ko05150 Staphylococcus aureus infection 11/376 36/7206 1.24400221714e-06 ko05166 HTLV-I infection 1/376 292/7206 4.84031616842e-06 ko00983 Drug metabolism - other enzymes 11/376 42/7206 6.67374999045e-06 ko04950 Maturity onset diabetes of the young 9/376 29/7206 1.0275891906e-05 ko04614 Renin-angiotensin system 7/376 18/7206 1.92126340505e-05 ko03320 PPAR signaling pathway 13/376 69/7206 4.63444846812e-05 ko04360 Axon guidance 1/376 233/7206 7.11211710467e-05 ko04964 Proximal tubule bicarbonate reclamation 8/376 29/7206 8.31301573366e-05 ko00591 Linoleic acid metabolism 7/376 22/7206 8.58279919028e-05 ko04972 Pancreatic secretion 16/376 111/7206 0.00018782771696 ko00380 Tryptophan metabolism 10/376 50/7206 0.000208794002219 ko04973 Carbohydrate digestion and absorption 9/376 42/7206 0.000250069417395 ko00643 Styrene degradation 3/376 4/7206 0.000542057501138 ko05204 Chemical carcinogenesis 9/376 48/7206 0.000712676584997 ko00260 Glycine, serine and threonine metabolism 9/376 48/7206 0.000712676584997 ko00980 Metabolism of xenobiotics by cytochrome P450 8/376 40/7206 0.000899548384318 ko01200 Carbon metabolism 16/376 128/7206 0.000954537153121 ko04144 Endocytosis 6/376 342/7206 0.00161946902582 ko05200 Pathways in cancer 12/376 492/7206 0.00225267064433 ko04740 Olfactory transduction 11/376 80/7206 0.00274514794395 ko04010 MAPK signaling pathway 6/376 321/7206 0.00296175595473 ko00630 Glyoxylate and dicarboxylate metabolism 7/376 38/7206 0.00308418969811 ko00140 Steroid hormone biosynthesis 7/376 41/7206 0.00480344583455 ko00590 Arachidonic acid metabolism 8/376 52/7206 0.00509938611028 ko05203 Viral carcinogenesis 5/376 277/7206 0.00548370422982 ko00830 Retinol metabolism 7/376 42/7206 0.00551211090491 ko04150 mTOR signaling pathway 2/376 184/7206 0.00626889767402 ko04141 Protein processing in endoplasmic reticulum 2/376 184/7206 0.00626889767402 ko04920 Adipocytokine signaling pathway 11/376 89/7206 0.00629692439947 ko00350 Tyrosine metabolism 6/376 33/7206 0.0064719363548 ko04110 Cell cycle 1/376 145/7206 0.00708476706405 ko05034 Alcoholism 4/376 238/7206 0.0073594084875 ko00340 Histidine metabolism 5/376 25/7206 0.00841855506371 ko05161 Hepatitis B 2/376 173/7206 0.00871696908466 ko05206 MicroRNAs in cancer 2/376 177/7206 0.00897874584525 ko04217 Necroptosis 2/376 178/7206 0.00909872579325 ko05010 Alzheimer's disease 3/376 202/7206 0.00968791515411 ko05169 Epstein-Barr virus infection 3/376 206/7206 0.00988988617071 ko00040 Pentose and glucuronate interconversions 5/376 26/7206 0.00998697002259 ko00270 Cysteine and methionine metabolism 7/376 47/7206 0.0102821667851 ko04120 Ubiquitin mediated proteolysis 1/376 138/7206 0.0103534310183 ko00982 Drug metabolism - cytochrome P450 6/376 37/7206 0.0114024925945 ko00710 Carbon fixation in photosynthetic organisms 5/376 27/7206 0.0117447743645 ko04550 Signaling pathways regulating pluripotency of stem cells 2/376 165/7206 0.012339904451 ko01230 Biosynthesis of amino acids 10/376 85/7206 0.0125828649544 ko02010 ABC transporters 6/376 39/7206 0.0146654652742 ko00592 alpha-Linolenic acid metabolism 4/376 19/7206 0.0151465785234 ko00120 Primary bile acid biosynthesis 4/376 20/7206 0.0181720609918 ko00565 Ether lipid metabolism 6/376 42/7206 0.020695738866 ko05162 Measles 1/376 120/7206 0.0212463946121 ko04666 Fc gamma R-mediated phagocytosis 1/376 122/7206 0.0215309993496 ko00100 Steroid biosynthesis 4/376 21/7206 0.0215471919723 ko04660 T cell receptor signaling pathway 1/376 124/7206 0.0220531091913 ko00480 Glutathione metabolism 7/376 55/7206 0.0232765900948 ko05133 Pertussis 10/376 87/7206 0.0238554006637 ko00232 Caffeine metabolism 2/376 5/7206 0.0244457716634 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/376 5/7206 0.0244457716634 ko00053 Ascorbate and aldarate metabolism 4/376 22/7206 0.025280974658 ko04216 Ferroptosis 6/376 44/7206 0.0255365836829 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/376 182/7206 0.0262236835413 ko00680 Methane metabolism 5/376 34/7206 0.0300844397957 ko00770 Pantothenate and CoA biosynthesis 3/376 14/7206 0.0333901812061 ko05224 Breast cancer 3/376 174/7206 0.0360401991341 ko04015 Rap1 signaling pathway 7/376 278/7206 0.0380769335842 ko04024 cAMP signaling pathway 7/376 279/7206 0.0381938906966 ko04742 Taste transduction 7/376 61/7206 0.0384361285645 ko04520 Adherens junction 1/376 103/7206 0.0440031627714 ko04659 Th17 cell differentiation 1/376 106/7206 0.0445002562507 ko00250 Alanine, aspartate and glutamate metabolism 5/376 38/7206 0.0458710398209 ko04933 AGE-RAGE signaling pathway in diabetic complications 2/376 135/7206 0.0484030618673 ko04072 Phospholipase D signaling pathway 4/376 197/7206 0.0484966869853 ko04146 Peroxisome 9/376 89/7206 0.0499254324565