ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	179/1097	423/7206	4.96011736582e-44
ko05033	Nicotine addiction	49/1097	56/7206	2.72815489776e-33
ko04724	Glutamatergic synapse	85/1097	152/7206	9.16512991219e-32
ko05032	Morphine addiction	68/1097	110/7206	3.05616147376e-29
ko04727	GABAergic synapse	65/1097	110/7206	2.22989259706e-26
ko04713	Circadian entrainment	69/1097	136/7206	1.21041859075e-22
ko04721	Synaptic vesicle cycle	50/1097	80/7206	4.32244334585e-22
ko04728	Dopaminergic synapse	80/1097	185/7206	1.84141756476e-20
ko04723	Retrograde endocannabinoid signaling	76/1097	175/7206	1.27415966688e-19
ko04725	Cholinergic synapse	71/1097	160/7206	4.89764854623e-19
ko04024	cAMP signaling pathway	96/1097	279/7206	4.62987227681e-16
ko04744	Phototransduction	27/1097	36/7206	1.50130567401e-15
ko04726	Serotonergic synapse	56/1097	137/7206	2.14004352322e-13
ko04742	Taste transduction	34/1097	61/7206	2.4585033787e-13
ko04911	Insulin secretion	49/1097	117/7206	2.38565897197e-12
ko04020	Calcium signaling pathway	84/1097	265/7206	5.8268707162e-12
ko04261	Adrenergic signaling in cardiomyocytes	69/1097	205/7206	3.21462792479e-11
ko04921	Oxytocin signaling pathway	69/1097	209/7206	6.23186438065e-11
ko05031	Amphetamine addiction	38/1097	91/7206	7.93802296795e-10
ko03040	Spliceosome	1/1097	145/7206	1.35397190189e-09
ko04720	Long-term potentiation	38/1097	99/7206	1.3317640925e-08
ko05030	Cocaine addiction	31/1097	73/7206	1.80579333895e-08
ko05203	Viral carcinogenesis	14/1097	277/7206	1.28649763635e-07
ko04970	Salivary secretion	34/1097	95/7206	6.85931575716e-07
ko04060	Cytokine-cytokine receptor interaction	8/1097	191/7206	1.75756301216e-06
ko05322	Systemic lupus erythematosus	5/1097	151/7206	3.03781718649e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1097	74/7206	5.26657482159e-06
ko03013	RNA transport	7/1097	166/7206	8.92587821313e-06
ko05164	Influenza A	7/1097	167/7206	9.1467412638e-06
ko04740	Olfactory transduction	28/1097	80/7206	1.06230746353e-05
ko04925	Aldosterone synthesis and secretion	34/1097	105/7206	1.24788524972e-05
ko04070	Phosphatidylinositol signaling system	35/1097	112/7206	1.48013303181e-05
ko04022	cGMP-PKG signaling pathway	57/1097	216/7206	1.8211214907e-05
ko05168	Herpes simplex infection	9/1097	182/7206	2.19823797129e-05
ko04010	MAPK signaling pathway	77/1097	321/7206	2.28127086128e-05
ko04966	Collecting duct acid secretion	13/1097	26/7206	3.28510865752e-05
ko05205	Proteoglycans in cancer	19/1097	271/7206	4.41759275912e-05
ko04971	Gastric acid secretion	31/1097	98/7206	4.54514536728e-05
ko04610	Complement and coagulation cascades	1/1097	79/7206	5.1839334932e-05
ko04072	Phospholipase D signaling pathway	51/1097	197/7206	7.61812446757e-05
ko04360	Axon guidance	58/1097	233/7206	8.68131093969e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1097	79/7206	9.32853793747e-05
ko04514	Cell adhesion molecules (CAMs)	37/1097	130/7206	0.000101585333671
ko04141	Protein processing in endoplasmic reticulum	11/1097	184/7206	0.000154616163438
ko04972	Pancreatic secretion	32/1097	111/7206	0.000247012763949
ko05169	Epstein-Barr virus infection	14/1097	206/7206	0.000251817618749
ko04621	NOD-like receptor signaling pathway	9/1097	157/7206	0.00029190781527
ko04260	Cardiac muscle contraction	29/1097	98/7206	0.000297610260091
ko03008	Ribosome biogenesis in eukaryotes	2/1097	79/7206	0.000409274161889
ko04730	Long-term depression	24/1097	78/7206	0.000646548661645
ko05162	Measles	6/1097	120/7206	0.000738904578785
ko05414	Dilated cardiomyopathy	31/1097	112/7206	0.000752569417264
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1097	59/7206	0.00086185951399
ko04745	Phototransduction - fly	14/1097	38/7206	0.000881461878338
ko04064	NF-kappa B signaling pathway	4/1097	96/7206	0.000888464977666
ko05140	Leishmaniasis	2/1097	75/7206	0.000935910580407
ko04924	Renin secretion	25/1097	86/7206	0.00120816276832
ko00240	Pyrimidine metabolism	6/1097	110/7206	0.00198839506256
ko00480	Glutathione metabolism	1/1097	55/7206	0.00208629248741
ko05110	Vibrio cholerae infection	19/1097	63/7206	0.00229393824867
ko04964	Proximal tubule bicarbonate reclamation	11/1097	29/7206	0.00237754770351
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1097	14/7206	0.00238434709222
ko04146	Peroxisome	4/1097	89/7206	0.00259303711473
ko05161	Hepatitis B	13/1097	173/7206	0.00262924592273
ko04110	Cell cycle	10/1097	145/7206	0.00327042708456
ko04612	Antigen processing and presentation	3/1097	77/7206	0.00346140394484
ko04640	Hematopoietic cell lineage	2/1097	64/7206	0.00429513391378
ko04120	Ubiquitin mediated proteolysis	10/1097	138/7206	0.00579224143051
ko04510	Focal adhesion	22/1097	240/7206	0.00604748363326
ko04540	Gap junction	31/1097	128/7206	0.00621318978375
ko04915	Estrogen signaling pathway	32/1097	131/7206	0.00641450909537
ko03420	Nucleotide excision repair	1/1097	46/7206	0.00698870593412
ko05145	Toxoplasmosis	9/1097	126/7206	0.00828150197896
ko04658	Th1 and Th2 cell differentiation	6/1097	96/7206	0.00981791879664
ko05133	Pertussis	5/1097	87/7206	0.010090418944
ko03022	Basal transcription factors	1/1097	44/7206	0.0104230030302
ko05144	Malaria	1/1097	45/7206	0.0106826548483
ko00071	Fatty acid degradation	1/1097	45/7206	0.0106826548483
ko04976	Bile secretion	21/1097	80/7206	0.0111020104386
ko04350	TGF-beta signaling pathway	7/1097	103/7206	0.0126687174497
ko05321	Inflammatory bowel disease (IBD)	2/1097	56/7206	0.0133299214972
ko03018	RNA degradation	5/1097	84/7206	0.0138848843004
ko04371	Apelin signaling pathway	39/1097	177/7206	0.0144359814815
ko04210	Apoptosis	16/1097	180/7206	0.0152722110964
ko04923	Regulation of lipolysis in adipocytes	20/1097	77/7206	0.0152977945475
ko05166	HTLV-I infection	30/1097	292/7206	0.0156254071451
ko04014	Ras signaling pathway	57/1097	279/7206	0.0170557313363
ko00330	Arginine and proline metabolism	3/1097	61/7206	0.0194356860367
ko04622	RIG-I-like receptor signaling pathway	3/1097	62/7206	0.0196019698589
ko04750	Inflammatory mediator regulation of TRP channels	28/1097	122/7206	0.0216073717233
ko00630	Glyoxylate and dicarboxylate metabolism	1/1097	38/7206	0.02306752242
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1097	100/7206	0.0235975982927
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1097	40/7206	0.0240780357382
ko00260	Glycine, serine and threonine metabolism	2/1097	48/7206	0.026389741876
ko05219	Bladder cancer	2/1097	48/7206	0.026389741876
ko04630	Jak-STAT signaling pathway	11/1097	132/7206	0.02688132505
ko03320	PPAR signaling pathway	4/1097	69/7206	0.0272578427623
ko04140	Autophagy - animal	15/1097	164/7206	0.0274666356584
ko04932	Non-alcoholic fatty liver disease (NAFLD)	17/1097	182/7206	0.0274824226742
ko05231	Choline metabolism in cancer	30/1097	134/7206	0.0279215600079
ko04710	Circadian rhythm	12/1097	43/7206	0.0305065186376
ko04657	IL-17 signaling pathway	6/1097	87/7206	0.0338504321098
ko04217	Necroptosis	17/1097	178/7206	0.0340278864003
ko00982	Drug metabolism - cytochrome P450	1/1097	37/7206	0.0352667520823
ko04930	Type II diabetes mellitus	14/1097	54/7206	0.0356177989824
ko04711	Circadian rhythm - fly	5/1097	13/7206	0.0360472153366
ko00562	Inositol phosphate metabolism	21/1097	89/7206	0.0362606431048
ko05016	Huntington's disease	22/1097	215/7206	0.0423453441791
ko05131	Shigellosis	6/1097	82/7206	0.0440644408376
ko04137	Mitophagy - animal	6/1097	82/7206	0.0440644408376
ko04626	Plant-pathogen interaction	6/1097	18/7206	0.044432203222
ko04071	Sphingolipid signaling pathway	34/1097	162/7206	0.0458806799938
ko04214	Apoptosis - fly	5/1097	72/7206	0.0478389972394
ko00310	Lysine degradation	5/1097	73/7206	0.0480594500609
ko04620	Toll-like receptor signaling pathway	8/1097	100/7206	0.048299077653
ko04115	p53 signaling pathway	5/1097	74/7206	0.0488345019371