ko pathway ratio_in_study ratio_in_pop p_value ko04111 Cell cycle - yeast 25/236 90/7206 3.80097865412e-17 ko03040 Spliceosome 29/236 145/7206 1.52153605747e-15 ko04110 Cell cycle 29/236 145/7206 1.52153605747e-15 ko03008 Ribosome biogenesis in eukaryotes 20/236 79/7206 4.30554359357e-13 ko03030 DNA replication 14/236 38/7206 5.35203317548e-12 ko04113 Meiosis - yeast 17/236 70/7206 5.42547792352e-11 ko03440 Homologous recombination 12/236 41/7206 3.92334184279e-09 ko03460 Fanconi anemia pathway 11/236 51/7206 5.51392170404e-07 ko00240 Pyrimidine metabolism 15/236 110/7206 2.52012038126e-06 ko03410 Base excision repair 9/236 38/7206 2.64569791328e-06 ko03430 Mismatch repair 7/236 22/7206 4.14168879389e-06 ko04151 PI3K-Akt signaling pathway 1/236 390/7206 4.92921888942e-05 ko03013 RNA transport 15/236 166/7206 0.000333927817659 ko04114 Oocyte meiosis 13/236 139/7206 0.00059807934238 ko03420 Nucleotide excision repair 7/236 46/7206 0.000664620116265 ko04015 Rap1 signaling pathway 1/236 278/7206 0.00160343657062 ko04024 cAMP signaling pathway 1/236 279/7206 0.00161156440871 ko00230 Purine metabolism 15/236 194/7206 0.00168765677851 ko04120 Ubiquitin mediated proteolysis 12/236 138/7206 0.00182046024066 ko04914 Progesterone-mediated oocyte maturation 10/236 104/7206 0.00205998096357 ko04810 Regulation of actin cytoskeleton 1/236 264/7206 0.00233166027617 ko04010 MAPK signaling pathway 2/236 321/7206 0.00321712400989 ko05166 HTLV-I infection 19/236 292/7206 0.00377204555014 ko05322 Systemic lupus erythematosus 12/236 151/7206 0.00385467057604 ko04510 Focal adhesion 1/236 240/7206 0.00496342172232 ko04530 Tight junction 1/236 228/7206 0.00722046389751 ko04014 Ras signaling pathway 2/236 279/7206 0.00899592814661 ko03015 mRNA surveillance pathway 8/236 93/7206 0.0109214835608 ko05205 Proteoglycans in cancer 2/236 271/7206 0.0131228693723 ko04062 Chemokine signaling pathway 1/236 201/7206 0.0151242188118 ko00670 One carbon pool by folate 3/236 20/7206 0.0261949818972 ko00310 Lysine degradation 6/236 73/7206 0.031793718916 ko04115 p53 signaling pathway 6/236 74/7206 0.0336892279083 ko04140 Autophagy - animal 1/236 164/7206 0.0452209995281 ko04910 Insulin signaling pathway 1/236 172/7206 0.0465653646687