ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	57/693	152/7206	6.3474556365e-21
ko04080	Neuroactive ligand-receptor interaction	102/693	423/7206	1.83554283313e-19
ko04713	Circadian entrainment	49/693	136/7206	2.74087629424e-17
ko05033	Nicotine addiction	28/693	56/7206	1.12655508498e-14
ko04728	Dopaminergic synapse	54/693	185/7206	2.06422368905e-14
ko04725	Cholinergic synapse	49/693	160/7206	4.5130283252e-14
ko04727	GABAergic synapse	37/693	110/7206	2.71990454135e-12
ko05032	Morphine addiction	37/693	110/7206	2.71990454135e-12
ko04723	Retrograde endocannabinoid signaling	48/693	175/7206	7.61516904036e-12
ko04721	Synaptic vesicle cycle	30/693	80/7206	1.42521592933e-11
ko04911	Insulin secretion	37/693	117/7206	2.20364617167e-11
ko04921	Oxytocin signaling pathway	49/693	209/7206	2.33240531676e-09
ko04020	Calcium signaling pathway	57/693	265/7206	3.37289122289e-09
ko04261	Adrenergic signaling in cardiomyocytes	47/693	205/7206	9.38783970193e-09
ko04024	cAMP signaling pathway	57/693	279/7206	3.31644366515e-08
ko04726	Serotonergic synapse	34/693	137/7206	1.39142006663e-07
ko04970	Salivary secretion	27/693	95/7206	1.43488962544e-07
ko04022	cGMP-PKG signaling pathway	43/693	216/7206	2.97323466596e-06
ko05322	Systemic lupus erythematosus	1/693	151/7206	8.02480258421e-06
ko05031	Amphetamine addiction	23/693	91/7206	1.07298422956e-05
ko04514	Cell adhesion molecules (CAMs)	29/693	130/7206	1.30986098324e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/693	74/7206	1.37724975204e-05
ko05168	Herpes simplex infection	3/693	182/7206	1.93487684151e-05
ko04730	Long-term depression	20/693	78/7206	3.19739212188e-05
ko04720	Long-term potentiation	23/693	99/7206	4.63160258821e-05
ko00010	Glycolysis / Gluconeogenesis	19/693	74/7206	4.91887989282e-05
ko04060	Cytokine-cytokine receptor interaction	4/693	191/7206	5.24362379441e-05
ko03040	Spliceosome	2/693	145/7206	8.93512214443e-05
ko04745	Phototransduction - fly	12/693	38/7206	0.00014647017213
ko05203	Viral carcinogenesis	10/693	277/7206	0.000162977413677
ko04120	Ubiquitin mediated proteolysis	2/693	138/7206	0.000194376581337
ko00680	Methane metabolism	11/693	34/7206	0.000217252263334
ko04360	Axon guidance	40/693	233/7206	0.000253135427412
ko04925	Aldosterone synthesis and secretion	22/693	105/7206	0.000356232937414
ko05164	Influenza A	4/693	167/7206	0.000446516995944
ko04972	Pancreatic secretion	23/693	111/7206	0.000450877813354
ko04540	Gap junction	25/693	128/7206	0.000656205279812
ko04270	Vascular smooth muscle contraction	28/693	154/7206	0.000794562219426
ko04010	MAPK signaling pathway	49/693	321/7206	0.000927633609512
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/693	14/7206	0.00118241215213
ko04922	Glucagon signaling pathway	24/693	128/7206	0.00123883724949
ko04924	Renin secretion	18/693	86/7206	0.00130490716682
ko04971	Gastric acid secretion	20/693	98/7206	0.0014094233176
ko04930	Type II diabetes mellitus	13/693	54/7206	0.00144248104424
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/693	79/7206	0.00145113093403
ko05030	Cocaine addiction	16/693	73/7206	0.00186953156855
ko04962	Vasopressin-regulated water reabsorption	13/693	58/7206	0.00286817518269
ko05414	Dilated cardiomyopathy	21/693	112/7206	0.00297526900079
ko05410	Hypertrophic cardiomyopathy (HCM)	19/693	100/7206	0.00323152615153
ko04371	Apelin signaling pathway	29/693	177/7206	0.00409762970827
ko05162	Measles	3/693	120/7206	0.00435598210496
ko03013	RNA transport	6/693	166/7206	0.00485510441114
ko04626	Plant-pathogen interaction	6/693	18/7206	0.00522897861187
ko04610	Complement and coagulation cascades	1/693	79/7206	0.00609741002321
ko03008	Ribosome biogenesis in eukaryotes	1/693	79/7206	0.00609741002321
ko04742	Taste transduction	13/693	61/7206	0.00660153123635
ko01230	Biosynthesis of amino acids	16/693	85/7206	0.00817166302185
ko04260	Cardiac muscle contraction	18/693	98/7206	0.00827204951736
ko00240	Pyrimidine metabolism	3/693	110/7206	0.00852570631407
ko05161	Hepatitis B	7/693	173/7206	0.00860888940684
ko04621	NOD-like receptor signaling pathway	6/693	157/7206	0.00891358512079
ko05140	Leishmaniasis	1/693	75/7206	0.0089776278471
ko00030	Pentose phosphate pathway	8/693	32/7206	0.00916348249504
ko04966	Collecting duct acid secretion	7/693	26/7206	0.00952571605765
ko04146	Peroxisome	2/693	89/7206	0.0108340829706
ko04150	mTOR signaling pathway	8/693	184/7206	0.0108555188619
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/693	59/7206	0.0117679027643
ko00710	Carbon fixation in photosynthetic organisms	7/693	27/7206	0.0118190510721
ko04214	Apoptosis - fly	1/693	72/7206	0.0135836476856
ko04630	Jak-STAT signaling pathway	5/693	132/7206	0.0167533901489
ko04964	Proximal tubule bicarbonate reclamation	7/693	29/7206	0.0175556251353
ko05166	HTLV-I infection	17/693	292/7206	0.0251682657083
ko04330	Notch signaling pathway	1/693	62/7206	0.0278192315453
ko05169	Epstein-Barr virus infection	11/693	206/7206	0.0308963982389
ko01524	Platinum drug resistance	2/693	76/7206	0.0310933846841
ko04550	Signaling pathways regulating pluripotency of stem cells	8/693	165/7206	0.0322633240919
ko05215	Prostate cancer	4/693	111/7206	0.0327760147626
ko04915	Estrogen signaling pathway	20/693	131/7206	0.0350260724992
ko04916	Melanogenesis	21/693	142/7206	0.0430157236451
ko01521	EGFR tyrosine kinase inhibitor resistance	4/693	106/7206	0.0440749770505
ko00310	Lysine degradation	2/693	73/7206	0.0440996278774
ko04510	Focal adhesion	14/693	240/7206	0.0443732545471
ko04657	IL-17 signaling pathway	3/693	87/7206	0.0444791390442
ko05016	Huntington's disease	12/693	215/7206	0.0448581372075