ko pathway ratio_in_study ratio_in_pop p_value ko04070 Phosphatidylinositol signaling system 14/193 112/7206 1.46413831514e-06 ko04020 Calcium signaling pathway 22/193 265/7206 2.01081815632e-06 ko04726 Serotonergic synapse 15/193 137/7206 3.34905936331e-06 ko04911 Insulin secretion 13/193 117/7206 1.31124689751e-05 ko04925 Aldosterone synthesis and secretion 12/193 105/7206 2.13485242978e-05 ko04080 Neuroactive ligand-receptor interaction 26/193 423/7206 6.18072092291e-05 ko04750 Inflammatory mediator regulation of TRP channels 12/193 122/7206 9.53861066547e-05 ko04921 Oxytocin signaling pathway 16/193 209/7206 0.000141427901335 ko04742 Taste transduction 8/193 61/7206 0.000199764315105 ko04724 Glutamatergic synapse 13/193 152/7206 0.000204155556216 ko04725 Cholinergic synapse 13/193 160/7206 0.000338812441118 ko04540 Gap junction 11/193 128/7206 0.000605848630563 ko04720 Long-term potentiation 9/193 99/7206 0.00127354112523 ko00564 Glycerophospholipid metabolism 9/193 99/7206 0.00127354112523 ko04024 cAMP signaling pathway 17/193 279/7206 0.00170013610005 ko04922 Glucagon signaling pathway 10/193 128/7206 0.00220178475178 ko04744 Phototransduction 5/193 36/7206 0.00251127500949 ko04915 Estrogen signaling pathway 10/193 131/7206 0.00261242737735 ko05032 Morphine addiction 9/193 110/7206 0.00265514874253 ko05031 Amphetamine addiction 8/193 91/7206 0.00291151087119 ko00010 Glycolysis / Gluconeogenesis 7/193 74/7206 0.00350427810828 ko04728 Dopaminergic synapse 12/193 185/7206 0.0039429892168 ko04971 Gastric acid secretion 8/193 98/7206 0.00460062693106 ko00230 Purine metabolism 12/193 194/7206 0.0057564378994 ko04723 Retrograde endocannabinoid signaling 11/193 175/7206 0.00718374600362 ko04918 Thyroid hormone synthesis 7/193 86/7206 0.00800213875255 ko05231 Choline metabolism in cancer 9/193 134/7206 0.00964829472004 ko04713 Circadian entrainment 9/193 136/7206 0.0105780189429 ko00680 Methane metabolism 4/193 34/7206 0.0123427457859 ko04970 Salivary secretion 7/193 95/7206 0.0134702211378 ko04912 GnRH signaling pathway 8/193 122/7206 0.0163899477257 ko04745 Phototransduction - fly 4/193 38/7206 0.0180884794026 ko04072 Phospholipase D signaling pathway 11/193 197/7206 0.0209302380497 ko04960 Aldosterone-regulated sodium reabsorption 4/193 41/7206 0.0233310272886 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/193 1/7206 0.026783236192 ko04710 Circadian rhythm 4/193 43/7206 0.0272883980706 ko04924 Renin secretion 6/193 86/7206 0.0273588545221 ko01040 Biosynthesis of unsaturated fatty acids 3/193 25/7206 0.0282094018984 ko04972 Pancreatic secretion 7/193 111/7206 0.0290588395309 ko00562 Inositol phosphate metabolism 6/193 89/7206 0.0316865309427 ko04068 FoxO signaling pathway 9/193 167/7206 0.0452260839031 ko04022 cGMP-PKG signaling pathway 11/193 216/7206 0.0486822438069