ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	61/727	152/7206	4.7880189376e-23
ko05033	Nicotine addiction	36/727	56/7206	6.80999232188e-23
ko04727	GABAergic synapse	45/727	110/7206	1.16701518945e-17
ko04728	Dopaminergic synapse	59/727	185/7206	1.16194911181e-16
ko05032	Morphine addiction	43/727	110/7206	4.66661068168e-16
ko04080	Neuroactive ligand-receptor interaction	97/727	423/7206	1.24477720358e-15
ko04721	Synaptic vesicle cycle	35/727	80/7206	4.40886029082e-15
ko04723	Retrograde endocannabinoid signaling	52/727	175/7206	2.03079756217e-13
ko04713	Circadian entrainment	44/727	136/7206	5.86059555701e-13
ko04725	Cholinergic synapse	46/727	160/7206	1.88004542766e-11
ko04024	cAMP signaling pathway	63/727	279/7206	3.75975863662e-10
ko04360	Axon guidance	54/727	233/7206	2.77208922195e-09
ko04911	Insulin secretion	34/727	117/7206	6.28462904823e-09
ko04514	Cell adhesion molecules (CAMs)	35/727	130/7206	3.30579659196e-08
ko05030	Cocaine addiction	23/727	73/7206	3.69756785852e-07
ko04744	Phototransduction	15/727	36/7206	7.2579577251e-07
ko04742	Taste transduction	20/727	61/7206	1.05140008792e-06
ko05203	Viral carcinogenesis	7/727	277/7206	1.23881685949e-06
ko04726	Serotonergic synapse	33/727	137/7206	1.74802868673e-06
ko03040	Spliceosome	1/727	145/7206	4.80094017456e-06
ko04261	Adrenergic signaling in cardiomyocytes	42/727	205/7206	5.58713948452e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/727	74/7206	7.71562448724e-06
ko05031	Amphetamine addiction	23/727	91/7206	2.34931653227e-05
ko04010	MAPK signaling pathway	56/727	321/7206	3.73094423182e-05
ko05164	Influenza A	3/727	167/7206	3.95816499086e-05
ko04060	Cytokine-cytokine receptor interaction	5/727	191/7206	0.000124632335212
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/727	14/7206	0.000187916133023
ko03013	RNA transport	4/727	166/7206	0.000210985056141
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/727	79/7206	0.000240362058936
ko01200	Carbon metabolism	2/727	128/7206	0.00027775965095
ko05205	Proteoglycans in cancer	11/727	271/7206	0.00028791152044
ko04621	NOD-like receptor signaling pathway	4/727	157/7206	0.000423473567433
ko04120	Ubiquitin mediated proteolysis	3/727	138/7206	0.000508171093703
ko04972	Pancreatic secretion	23/727	111/7206	0.000674028680822
ko05168	Herpes simplex infection	6/727	182/7206	0.00101865363475
ko04720	Long-term potentiation	20/727	99/7206	0.00210125331472
ko05322	Systemic lupus erythematosus	5/727	151/7206	0.00249484131844
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/727	182/7206	0.00256097282655
ko04137	Mitophagy - animal	1/727	82/7206	0.00271313281875
ko03018	RNA degradation	1/727	84/7206	0.00281193073219
ko05162	Measles	3/727	120/7206	0.00311926750215
ko05169	Epstein-Barr virus infection	9/727	206/7206	0.0032396794985
ko04217	Necroptosis	7/727	178/7206	0.00347550660641
ko03008	Ribosome biogenesis in eukaryotes	1/727	79/7206	0.00404093236284
ko04921	Oxytocin signaling pathway	34/727	209/7206	0.00480227112014
ko04260	Cardiac muscle contraction	19/727	98/7206	0.00580036974353
ko00010	Glycolysis / Gluconeogenesis	1/727	74/7206	0.00587778062228
ko04141	Protein processing in endoplasmic reticulum	8/727	184/7206	0.00605085669135
ko04964	Proximal tubule bicarbonate reclamation	8/727	29/7206	0.00647419844009
ko04730	Long-term depression	16/727	78/7206	0.00660025765102
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/727	59/7206	0.00691596278863
ko04512	ECM-receptor interaction	16/727	79/7206	0.00698073444243
ko04146	Peroxisome	2/727	89/7206	0.00744554534267
ko04976	Bile secretion	16/727	80/7206	0.00744682743699
ko04140	Autophagy - animal	7/727	164/7206	0.0084616331808
ko04970	Salivary secretion	18/727	95/7206	0.00873514985486
ko04214	Apoptosis - fly	1/727	72/7206	0.00893198957319
ko04391	Hippo signaling pathway - fly	17/727	90/7206	0.0119150157268
ko04138	Autophagy - yeast	2/727	81/7206	0.0152056434404
ko04064	NF-kappa B signaling pathway	3/727	96/7206	0.0164295530502
ko00564	Glycerophospholipid metabolism	3/727	99/7206	0.0169717384448
ko04640	Hematopoietic cell lineage	1/727	64/7206	0.0191664308923
ko04014	Ras signaling pathway	40/727	279/7206	0.0196048790916
ko04930	Type II diabetes mellitus	11/727	54/7206	0.020351140451
ko04612	Antigen processing and presentation	2/727	77/7206	0.0216423744521
ko04218	Cellular senescence	9/727	177/7206	0.0224161207478
ko00240	Pyrimidine metabolism	4/727	110/7206	0.0237277234976
ko04611	Platelet activation	8/727	163/7206	0.0245224434875
ko05414	Dilated cardiomyopathy	19/727	112/7206	0.0249468706069
ko04020	Calcium signaling pathway	38/727	265/7206	0.0282981504995
ko04630	Jak-STAT signaling pathway	6/727	132/7206	0.0284144249086
ko05140	Leishmaniasis	2/727	75/7206	0.0313958692001
ko00515	Mannose type O-glycan biosynthesis	6/727	25/7206	0.0344275964035
ko05166	HTLV-I infection	19/727	292/7206	0.0369890565653
ko04974	Protein digestion and absorption	16/727	96/7206	0.0394101159168
ko00480	Glutathione metabolism	1/727	55/7206	0.0399692465267
ko04966	Collecting duct acid secretion	6/727	26/7206	0.0410731857273
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	6/727	26/7206	0.0410731857273
ko01230	Biosynthesis of amino acids	3/727	85/7206	0.0443072446624
ko05133	Pertussis	3/727	87/7206	0.0457607635009
ko05016	Huntington's disease	13/727	215/7206	0.04968930413
ko04211	Longevity regulating pathway	6/727	123/7206	0.0498784572647