ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 23/392 68/7206 3.67072363165e-13 ko04550 Signaling pathways regulating pluripotency of stem cells 35/392 165/7206 1.56208445688e-12 ko05224 Breast cancer 31/392 174/7206 3.08147965041e-09 ko04340 Hedgehog signaling pathway 16/392 58/7206 4.22143069811e-08 ko05202 Transcriptional misregulation in cancer 30/392 188/7206 7.66927129213e-08 ko04950 Maturity onset diabetes of the young 11/392 29/7206 1.52838093717e-07 ko04360 Axon guidance 33/392 233/7206 3.12286923894e-07 ko04390 Hippo signaling pathway 28/392 188/7206 9.08642455699e-07 ko05200 Pathways in cancer 53/392 492/7206 1.37850355868e-06 ko04512 ECM-receptor interaction 15/392 79/7206 1.81071601509e-05 ko05205 Proteoglycans in cancer 32/392 271/7206 2.77418220605e-05 ko04310 Wnt signaling pathway 24/392 181/7206 4.07737646371e-05 ko04330 Notch signaling pathway 12/392 62/7206 0.000102821315324 ko04510 Focal adhesion 28/392 240/7206 0.000116108961126 ko04916 Melanogenesis 19/392 142/7206 0.00022875163774 ko05222 Small cell lung cancer 14/392 89/7206 0.000285022155856 ko04391 Hippo signaling pathway - fly 13/392 90/7206 0.00107241372584 ko05010 Alzheimer's disease 2/392 202/7206 0.001464141024 ko04151 PI3K-Akt signaling pathway 36/392 390/7206 0.00173397728733 ko04974 Protein digestion and absorption 13/392 96/7206 0.00195986736689 ko04072 Phospholipase D signaling pathway 2/392 197/7206 0.00211162808731 ko03050 Proteasome 9/392 54/7206 0.00228323811643 ko05012 Parkinson's disease 1/392 155/7206 0.00337957624917 ko04350 TGF-beta signaling pathway 13/392 103/7206 0.00368425367213 ko04341 Hedgehog signaling pathway - fly 7/392 38/7206 0.003891206036 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/392 182/7206 0.0043083256191 ko04080 Neuroactive ligand-receptor interaction 11/392 423/7206 0.00550223321886 ko04392 Hippo signaling pathway -multiple species 6/392 31/7206 0.00575533953958 ko04723 Retrograde endocannabinoid signaling 2/392 175/7206 0.00615264845402 ko04144 Endocytosis 8/392 342/7206 0.00679654216178 ko04062 Chemokine signaling pathway 3/392 201/7206 0.00691468733652 ko04120 Ubiquitin mediated proteolysis 1/392 138/7206 0.00697705676607 ko05130 Pathogenic Escherichia coli infection 10/392 77/7206 0.00846562230965 ko03010 Ribosome 1/392 129/7206 0.010062593467 ko05206 MicroRNAs in cancer 18/392 177/7206 0.0103891157266 ko05166 HTLV-I infection 26/392 292/7206 0.0117817763735 ko04611 Platelet activation 2/392 163/7206 0.0127671612179 ko00190 Oxidative phosphorylation 1/392 127/7206 0.0153595003329 ko03410 Base excision repair 6/392 38/7206 0.015675484822 ko04724 Glutamatergic synapse 2/392 152/7206 0.0174300197522 ko04020 Calcium signaling pathway 6/392 265/7206 0.0179278317917 ko04921 Oxytocin signaling pathway 4/392 209/7206 0.0190219348988 ko04514 Cell adhesion molecules (CAMs) 13/392 130/7206 0.0296974163898 ko05032 Morphine addiction 1/392 110/7206 0.0310354532188 ko00350 Tyrosine metabolism 5/392 33/7206 0.0313294209835 ko04972 Pancreatic secretion 1/392 111/7206 0.0314066996197 ko04726 Serotonergic synapse 2/392 137/7206 0.0344699143399 ko00230 Purine metabolism 4/392 194/7206 0.0351154232343 ko04612 Antigen processing and presentation 9/392 77/7206 0.0363253722939 ko04720 Long-term potentiation 1/392 99/7206 0.043823900857 ko05168 Herpes simplex infection 4/392 182/7206 0.0467607555104 ko01200 Carbon metabolism 2/392 128/7206 0.0479565805042 ko04270 Vascular smooth muscle contraction 3/392 154/7206 0.0483217708037 ko04621 NOD-like receptor signaling pathway 3/392 157/7206 0.0485345340654 ko05218 Melanoma 9/392 85/7206 0.0489417336916 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/392 26/7206 0.0499249593055