ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 31/426 68/7206 8.39849271311e-21 ko04360 Axon guidance 49/426 233/7206 1.62815394111e-15 ko04974 Protein digestion and absorption 30/426 96/7206 9.62955065679e-15 ko04550 Signaling pathways regulating pluripotency of stem cells 38/426 165/7206 1.44195660803e-13 ko05224 Breast cancer 39/426 174/7206 1.73294634888e-13 ko04390 Hippo signaling pathway 40/426 188/7206 5.13494055222e-13 ko05200 Pathways in cancer 70/426 492/7206 1.5318193512e-12 ko04512 ECM-receptor interaction 24/426 79/7206 9.67879353805e-12 ko04310 Wnt signaling pathway 33/426 181/7206 4.24151359643e-09 ko05205 Proteoglycans in cancer 42/426 271/7206 5.32665652761e-09 ko04916 Melanogenesis 28/426 142/7206 1.10928200597e-08 ko04151 PI3K-Akt signaling pathway 51/426 390/7206 5.11065537524e-08 ko04340 Hedgehog signaling pathway 15/426 58/7206 8.34396599317e-07 ko04510 Focal adhesion 34/426 240/7206 1.77441169253e-06 ko05410 Hypertrophic cardiomyopathy (HCM) 18/426 100/7206 1.8390414024e-05 ko04950 Maturity onset diabetes of the young 9/426 29/7206 2.80688824207e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 15/426 79/7206 4.79749721285e-05 ko04260 Cardiac muscle contraction 17/426 98/7206 5.13153296272e-05 ko04391 Hippo signaling pathway - fly 15/426 90/7206 0.000223793019236 ko05414 Dilated cardiomyopathy 17/426 112/7206 0.000280361752888 ko03013 RNA transport 1/426 166/7206 0.000704057955626 ko04724 Glutamatergic synapse 1/426 152/7206 0.00151050938316 ko05203 Viral carcinogenesis 5/426 277/7206 0.00156840555809 ko05034 Alcoholism 4/426 238/7206 0.00197109577111 ko04978 Mineral absorption 8/426 40/7206 0.00201098061837 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/426 182/7206 0.00209408435994 ko04142 Lysosome 1/426 151/7206 0.00235580278255 ko05322 Systemic lupus erythematosus 1/426 151/7206 0.00235580278255 ko05169 Epstein-Barr virus infection 3/426 206/7206 0.00247537337485 ko04218 Cellular senescence 2/426 177/7206 0.00306528055661 ko04217 Necroptosis 2/426 178/7206 0.00311782272925 ko04120 Ubiquitin mediated proteolysis 1/426 138/7206 0.00322646943821 ko05164 Influenza A 2/426 167/7206 0.00424154034259 ko05202 Transcriptional misregulation in cancer 21/426 188/7206 0.00429057364953 ko04514 Cell adhesion molecules (CAMs) 16/426 130/7206 0.00435471536183 ko04350 TGF-beta signaling pathway 14/426 103/7206 0.00459406150962 ko05167 Kaposi's sarcoma-associated herpesvirus infection 3/426 191/7206 0.00489366172795 ko04015 Rap1 signaling pathway 28/426 278/7206 0.00585798930715 ko04261 Adrenergic signaling in cardiomyocytes 22/426 205/7206 0.00614089058988 ko04392 Hippo signaling pathway -multiple species 6/426 31/7206 0.00857600813966 ko05162 Measles 1/426 120/7206 0.00998390708607 ko04150 mTOR signaling pathway 20/426 184/7206 0.0100299219891 ko04723 Retrograde endocannabinoid signaling 3/426 175/7206 0.0135771870319 ko04062 Chemokine signaling pathway 4/426 201/7206 0.013998460566 ko05218 Melanoma 11/426 85/7206 0.0164690855099 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 5/426 26/7206 0.0165302874064 ko04114 Oocyte meiosis 2/426 139/7206 0.0171800596867 ko05222 Small cell lung cancer 11/426 89/7206 0.0195368933552 ko05206 MicroRNAs in cancer 18/426 177/7206 0.0224286414537 ko04630 Jak-STAT signaling pathway 2/426 132/7206 0.0242072061879 ko00564 Glycerophospholipid metabolism 1/426 99/7206 0.0301944636989 ko04620 Toll-like receptor signaling pathway 1/426 100/7206 0.030368717708 ko05166 HTLV-I infection 26/426 292/7206 0.0312750297582 ko04810 Regulation of actin cytoskeleton 24/426 264/7206 0.0325333883305 ko05010 Alzheimer's disease 5/426 202/7206 0.0330613807097 ko04660 T cell receptor signaling pathway 2/426 124/7206 0.0339429143962 ko01200 Carbon metabolism 2/426 128/7206 0.0347148579797 ko04210 Apoptosis 4/426 180/7206 0.0352852213611 ko05142 Chagas disease (American trypanosomiasis) 2/426 130/7206 0.0356402065896 ko04064 NF-kappa B signaling pathway 1/426 96/7206 0.0452487988478 ko00430 Taurine and hypotaurine metabolism 3/426 14/7206 0.0458717129655 ko05144 Malaria 6/426 45/7206 0.0475367065942 ko05161 Hepatitis B 4/426 173/7206 0.0476274146829 ko04110 Cell cycle 3/426 145/7206 0.0483023837008