ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/955	423/7206	1.27403337165e-42
ko04724	Glutamatergic synapse	78/955	152/7206	4.79547862163e-30
ko05033	Nicotine addiction	44/955	56/7206	1.13853492967e-28
ko05032	Morphine addiction	62/955	110/7206	4.83385085582e-27
ko04727	GABAergic synapse	59/955	110/7206	2.96450862953e-24
ko04728	Dopaminergic synapse	76/955	185/7206	1.3641779883e-21
ko04713	Circadian entrainment	63/955	136/7206	2.27431923155e-21
ko04721	Synaptic vesicle cycle	46/955	80/7206	7.81454441781e-21
ko04723	Retrograde endocannabinoid signaling	70/955	175/7206	3.45082994813e-19
ko04725	Cholinergic synapse	65/955	160/7206	2.63334721242e-18
ko04911	Insulin secretion	50/955	117/7206	2.06192087913e-15
ko04024	cAMP signaling pathway	84/955	279/7206	4.78827140294e-14
ko04726	Serotonergic synapse	52/955	137/7206	1.87132121827e-13
ko04742	Taste transduction	32/955	61/7206	2.37904184004e-13
ko04020	Calcium signaling pathway	77/955	265/7206	7.03106618686e-12
ko04921	Oxytocin signaling pathway	64/955	209/7206	2.72412886862e-11
ko05031	Amphetamine addiction	37/955	91/7206	5.79135324835e-11
ko04744	Phototransduction	21/955	36/7206	2.33743085503e-10
ko04261	Adrenergic signaling in cardiomyocytes	61/955	205/7206	3.48550866044e-10
ko05030	Cocaine addiction	29/955	73/7206	1.32237863745e-08
ko04720	Long-term potentiation	35/955	99/7206	1.5551873577e-08
ko03040	Spliceosome	1/955	145/7206	3.63212850892e-08
ko04925	Aldosterone synthesis and secretion	34/955	105/7206	2.89119592282e-07
ko05322	Systemic lupus erythematosus	3/955	151/7206	1.39375453225e-06
ko04970	Salivary secretion	30/955	95/7206	3.83684065175e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/955	74/7206	4.58651873849e-06
ko04971	Gastric acid secretion	30/955	98/7206	6.10221939064e-06
ko04514	Cell adhesion molecules (CAMs)	36/955	130/7206	1.00359635351e-05
ko04010	MAPK signaling pathway	69/955	321/7206	3.14648920009e-05
ko04060	Cytokine-cytokine receptor interaction	8/955	191/7206	3.31637662162e-05
ko03013	RNA transport	6/955	166/7206	3.87640724159e-05
ko05164	Influenza A	6/955	167/7206	3.95646091094e-05
ko04972	Pancreatic secretion	31/955	111/7206	4.9314017778e-05
ko04120	Ubiquitin mediated proteolysis	4/955	138/7206	6.02186005302e-05
ko05203	Viral carcinogenesis	16/955	277/7206	6.06868176077e-05
ko05168	Herpes simplex infection	8/955	182/7206	8.98591975576e-05
ko04621	NOD-like receptor signaling pathway	6/955	157/7206	0.0001106717016
ko04740	Olfactory transduction	23/955	80/7206	0.000200087895681
ko04022	cGMP-PKG signaling pathway	48/955	216/7206	0.00021785900652
ko04141	Protein processing in endoplasmic reticulum	9/955	184/7206	0.000243446884484
ko04610	Complement and coagulation cascades	1/955	79/7206	0.000317809688828
ko05162	Measles	4/955	120/7206	0.000346903546689
ko04260	Cardiac muscle contraction	26/955	98/7206	0.000414237279703
ko04612	Antigen processing and presentation	1/955	77/7206	0.000499616153866
ko04360	Axon guidance	50/955	233/7206	0.000522875847638
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/955	79/7206	0.000589313558109
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/955	59/7206	0.000638229487506
ko04745	Phototransduction - fly	13/955	38/7206	0.000789259559666
ko04072	Phospholipase D signaling pathway	43/955	197/7206	0.000849217512248
ko04730	Long-term depression	21/955	78/7206	0.00111385587744
ko05110	Vibrio cholerae infection	18/955	63/7206	0.00112139215488
ko04966	Collecting duct acid secretion	10/955	26/7206	0.00113487080494
ko04110	Cell cycle	7/955	145/7206	0.00117366093583
ko04064	NF-kappa B signaling pathway	3/955	96/7206	0.00124798091877
ko05205	Proteoglycans in cancer	19/955	271/7206	0.00130645653843
ko04930	Type II diabetes mellitus	16/955	54/7206	0.00167552100683
ko04070	Phosphatidylinositol signaling system	27/955	112/7206	0.00170016175528
ko05161	Hepatitis B	10/955	173/7206	0.00201330728554
ko03008	Ribosome biogenesis in eukaryotes	2/955	79/7206	0.00218586543732
ko04640	Hematopoietic cell lineage	1/955	64/7206	0.00238455063975
ko04146	Peroxisome	3/955	89/7206	0.00255920736147
ko04750	Inflammatory mediator regulation of TRP channels	28/955	122/7206	0.0028162767848
ko04710	Circadian rhythm	13/955	43/7206	0.00282794285502
ko05140	Leishmaniasis	2/955	75/7206	0.00312115420511
ko04915	Estrogen signaling pathway	29/955	131/7206	0.00409729257731
ko04630	Jak-STAT signaling pathway	7/955	132/7206	0.00410333599955
ko05414	Dilated cardiomyopathy	26/955	112/7206	0.00438878923145
ko05169	Epstein-Barr virus infection	14/955	206/7206	0.00458834671119
ko04924	Renin secretion	21/955	86/7206	0.00562468852019
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/955	14/7206	0.00620987521612
ko04210	Apoptosis	12/955	180/7206	0.00712632271857
ko00280	Valine, leucine and isoleucine degradation	1/955	54/7206	0.00765623062226
ko00480	Glutathione metabolism	1/955	55/7206	0.00788793284605
ko04964	Proximal tubule bicarbonate reclamation	9/955	29/7206	0.0102145941561
ko05215	Prostate cancer	6/955	111/7206	0.0106060068493
ko04976	Bile secretion	19/955	80/7206	0.0114425846273
ko04540	Gap junction	27/955	128/7206	0.012003752197
ko00310	Lysine degradation	3/955	73/7206	0.0147749528389
ko05133	Pertussis	4/955	87/7206	0.015610007017
ko05410	Hypertrophic cardiomyopathy (HCM)	22/955	100/7206	0.0162109613744
ko05219	Bladder cancer	1/955	48/7206	0.016843212268
ko04218	Cellular senescence	13/955	177/7206	0.0178550381615
ko00330	Arginine and proline metabolism	2/955	61/7206	0.0204990932929
ko04711	Circadian rhythm - fly	5/955	13/7206	0.020793051554
ko03018	RNA degradation	4/955	84/7206	0.0216983740741
ko03022	Basal transcription factors	1/955	44/7206	0.0245867823409
ko00071	Fatty acid degradation	1/955	45/7206	0.0249218965658
ko03420	Nucleotide excision repair	1/955	46/7206	0.0257525018787
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/955	182/7206	0.0260367354205
ko05166	HTLV-I infection	26/955	292/7206	0.0271202728713
ko05200	Pathways in cancer	49/955	492/7206	0.027237046282
ko05321	Inflammatory bowel disease (IBD)	2/955	56/7206	0.0281122259109
ko03320	PPAR signaling pathway	3/955	69/7206	0.0299775379411
ko00240	Pyrimidine metabolism	7/955	110/7206	0.0323593412719
ko05206	MicroRNAs in cancer	14/955	177/7206	0.0325926282206
ko04657	IL-17 signaling pathway	5/955	87/7206	0.0374733767682
ko04014	Ras signaling pathway	49/955	279/7206	0.037772775091
ko05231	Choline metabolism in cancer	26/955	134/7206	0.0393650558246
ko05418	Fluid shear stress and atherosclerosis	14/955	173/7206	0.0410023843316
ko04510	Focal adhesion	21/955	240/7206	0.0412926422855
ko04371	Apelin signaling pathway	33/955	177/7206	0.0423455503256
ko04922	Glucagon signaling pathway	25/955	128/7206	0.0470093375967
ko04658	Th1 and Th2 cell differentiation	6/955	96/7206	0.0470469778077