ko pathway ratio_in_study ratio_in_pop p_value ko04727 GABAergic synapse 26/303 110/7206 2.79850513979e-13 ko05033 Nicotine addiction 19/303 56/7206 4.2087097524e-13 ko04724 Glutamatergic synapse 29/303 152/7206 3.7951862328e-12 ko04728 Dopaminergic synapse 32/303 185/7206 4.43994510349e-12 ko04721 Synaptic vesicle cycle 20/303 80/7206 5.74421386674e-11 ko04744 Phototransduction 14/303 36/7206 6.60505817007e-11 ko05032 Morphine addiction 22/303 110/7206 6.58200503599e-10 ko04723 Retrograde endocannabinoid signaling 27/303 175/7206 3.22101399245e-09 ko04725 Cholinergic synapse 25/303 160/7206 9.73331688771e-09 ko04080 Neuroactive ligand-receptor interaction 42/303 423/7206 1.25466641124e-07 ko04713 Circadian entrainment 19/303 136/7206 3.50350494555e-06 ko04024 cAMP signaling pathway 29/303 279/7206 5.11461167769e-06 ko04911 Insulin secretion 17/303 117/7206 6.7383358697e-06 ko05030 Cocaine addiction 12/303 73/7206 4.50267933421e-05 ko05031 Amphetamine addiction 13/303 91/7206 9.89094144322e-05 ko04514 Cell adhesion molecules (CAMs) 16/303 130/7206 0.000101004507357 ko04740 Olfactory transduction 11/303 80/7206 0.000474336172312 ko04726 Serotonergic synapse 15/303 137/7206 0.000599778274408 ko04742 Taste transduction 9/303 61/7206 0.000919714561877 ko05014 Amyotrophic lateral sclerosis (ALS) 10/303 74/7206 0.000979479351753 ko05203 Viral carcinogenesis 2/303 277/7206 0.00107325270686 ko04261 Adrenergic signaling in cardiomyocytes 19/303 205/7206 0.00109452770142 ko04010 MAPK signaling pathway 25/303 321/7206 0.00252545746307 ko05205 Proteoglycans in cancer 3/303 271/7206 0.0050370162319 ko04974 Protein digestion and absorption 10/303 96/7206 0.00682547527756 ko05016 Huntington's disease 2/303 215/7206 0.00887891401455 ko03013 RNA transport 1/303 166/7206 0.010339384447 ko04921 Oxytocin signaling pathway 16/303 209/7206 0.0206963547386 ko04260 Cardiac muscle contraction 9/303 98/7206 0.0216294999229 ko04142 Lysosome 1/303 151/7206 0.0218917787993 ko05322 Systemic lupus erythematosus 1/303 151/7206 0.0218917787993 ko04930 Type II diabetes mellitus 6/303 54/7206 0.0249253560614 ko04060 Cytokine-cytokine receptor interaction 2/303 191/7206 0.0257429693731 ko04810 Regulation of actin cytoskeleton 4/303 264/7206 0.0267711803839 ko04360 Axon guidance 17/303 233/7206 0.0285394887382 ko00190 Oxidative phosphorylation 1/303 127/7206 0.0447713339886 ko04630 Jak-STAT signaling pathway 1/303 132/7206 0.0453745634457 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 7/303 79/7206 0.0476044155279 ko04512 ECM-receptor interaction 7/303 79/7206 0.0476044155279 ko04140 Autophagy - animal 2/303 164/7206 0.0487512410503 ko05164 Influenza A 2/303 167/7206 0.0489797081051 ko04068 FoxO signaling pathway 2/303 167/7206 0.0489797081051 ko05169 Epstein-Barr virus infection 3/303 206/7206 0.0498928436384