ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 21/275 79/7206 7.81478824026e-13 ko04974 Protein digestion and absorption 19/275 96/7206 2.4081542636e-09 ko04060 Cytokine-cytokine receptor interaction 26/275 191/7206 1.22819497862e-08 ko04510 Focal adhesion 27/275 240/7206 3.62825639967e-07 ko00643 Styrene degradation 4/275 4/7206 2.07682281386e-06 ko05146 Amoebiasis 15/275 99/7206 4.35010417695e-06 ko05410 Hypertrophic cardiomyopathy (HCM) 14/275 100/7206 2.30829431895e-05 ko04933 AGE-RAGE signaling pathway in diabetic complications 16/275 135/7206 5.03613281549e-05 ko05205 Proteoglycans in cancer 25/275 271/7206 5.60545086559e-05 ko00565 Ether lipid metabolism 8/275 42/7206 0.00015482210337 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 11/275 79/7206 0.000183659249448 ko00350 Tyrosine metabolism 7/275 33/7206 0.000198652651697 ko05414 Dilated cardiomyopathy 13/275 112/7206 0.000315271478288 ko04668 TNF signaling pathway 13/275 120/7206 0.000618968211217 ko04912 GnRH signaling pathway 13/275 122/7206 0.000725134595509 ko04810 Regulation of actin cytoskeleton 21/275 264/7206 0.00143118861041 ko04657 IL-17 signaling pathway 10/275 87/7206 0.00165837186843 ko04151 PI3K-Akt signaling pathway 27/275 390/7206 0.00245887378679 ko00980 Metabolism of xenobiotics by cytochrome P450 6/275 40/7206 0.00376210155051 ko00140 Steroid hormone biosynthesis 6/275 41/7206 0.00426902147546 ko04611 Platelet activation 14/275 163/7206 0.00530565807771 ko05133 Pertussis 9/275 87/7206 0.00570201002741 ko00120 Primary bile acid biosynthesis 4/275 20/7206 0.00619842515555 ko04666 Fc gamma R-mediated phagocytosis 11/275 122/7206 0.0067111995024 ko05418 Fluid shear stress and atherosclerosis 14/275 173/7206 0.00732353276754 ko04670 Leukocyte transendothelial migration 13/275 151/7206 0.00758089581795 ko05160 Hepatitis C 13/275 153/7206 0.00795776861015 ko04621 NOD-like receptor signaling pathway 13/275 157/7206 0.00891864273673 ko05204 Chemical carcinogenesis 6/275 48/7206 0.00933124679948 ko05219 Bladder cancer 6/275 48/7206 0.00933124679948 ko04640 Hematopoietic cell lineage 7/275 64/7206 0.0105670288401 ko04064 NF-kappa B signaling pathway 9/275 96/7206 0.0107161462243 ko04672 Intestinal immune network for IgA production 5/275 37/7206 0.0125078411315 ko00982 Drug metabolism - cytochrome P450 5/275 37/7206 0.0125078411315 ko05131 Shigellosis 8/275 82/7206 0.0125731053016 ko05142 Chagas disease (American trypanosomiasis) 11/275 130/7206 0.0167064925567 ko00480 Glutathione metabolism 6/275 55/7206 0.0176771561829 ko05016 Huntington's disease 2/275 215/7206 0.0177888201043 ko04380 Osteoclast differentiation 11/275 134/7206 0.0183478566991 ko05222 Small cell lung cancer 8/275 89/7206 0.0198538535895 ko05134 Legionellosis 7/275 74/7206 0.0222235052382 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/275 92/7206 0.0237471673427 ko01524 Platinum drug resistance 7/275 76/7206 0.0253299239132 ko05144 Malaria 5/275 45/7206 0.0274258318173 ko05145 Toxoplasmosis 10/275 126/7206 0.0289800597939 ko05012 Parkinson's disease 1/275 155/7206 0.0315651434127 ko05143 African trypanosomiasis 4/275 32/7206 0.0322077556188 ko04215 Apoptosis - multiple species 5/275 47/7206 0.0323948109047 ko05164 Influenza A 12/275 167/7206 0.0365484256062 ko00401 Novobiocin biosynthesis 1/275 1/7206 0.0381626422426 ko00500 Starch and sucrose metabolism 4/275 35/7206 0.0429394171508 ko04110 Cell cycle 1/275 145/7206 0.0454889352452 ko05206 MicroRNAs in cancer 12/275 177/7206 0.0455679312907 ko00590 Arachidonic acid metabolism 5/275 52/7206 0.0471487507281