ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	174/1085	423/7206	2.02986729891e-41
ko04724	Glutamatergic synapse	82/1085	152/7206	1.58958946834e-29
ko05033	Nicotine addiction	44/1085	56/7206	2.76356318962e-26
ko05032	Morphine addiction	62/1085	110/7206	6.27248992939e-24
ko04713	Circadian entrainment	69/1085	136/7206	6.29337477849e-23
ko04728	Dopaminergic synapse	83/1085	185/7206	8.42932014141e-23
ko04727	GABAergic synapse	58/1085	110/7206	1.62637275504e-20
ko04725	Cholinergic synapse	70/1085	160/7206	1.22548352831e-18
ko04721	Synaptic vesicle cycle	45/1085	80/7206	1.22271293147e-17
ko04723	Retrograde endocannabinoid signaling	71/1085	175/7206	1.00704413507e-16
ko04024	cAMP signaling pathway	93/1085	279/7206	7.25525260411e-15
ko04742	Taste transduction	35/1085	61/7206	2.33154856901e-14
ko04911	Insulin secretion	51/1085	117/7206	8.02049751026e-14
ko04020	Calcium signaling pathway	87/1085	265/7206	1.31576160554e-13
ko04726	Serotonergic synapse	55/1085	137/7206	5.3756604059e-13
ko04360	Axon guidance	78/1085	233/7206	9.47221675924e-13
ko04921	Oxytocin signaling pathway	71/1085	209/7206	4.40426778847e-12
ko05031	Amphetamine addiction	40/1085	91/7206	2.93747843434e-11
ko04261	Adrenergic signaling in cardiomyocytes	65/1085	205/7206	1.02521308495e-09
ko03040	Spliceosome	1/1085	145/7206	2.2185573435e-09
ko04744	Phototransduction	21/1085	36/7206	2.6010267305e-09
ko04720	Long-term potentiation	38/1085	99/7206	9.77041938706e-09
ko04970	Salivary secretion	35/1085	95/7206	1.24928539181e-07
ko03013	RNA transport	5/1085	166/7206	4.68562850995e-07
ko05203	Viral carcinogenesis	15/1085	277/7206	4.93290223756e-07
ko05322	Systemic lupus erythematosus	4/1085	151/7206	7.55706014218e-07
ko04060	Cytokine-cytokine receptor interaction	8/1085	191/7206	1.7482118778e-06
ko04740	Olfactory transduction	29/1085	80/7206	2.2001534427e-06
ko04621	NOD-like receptor signaling pathway	5/1085	157/7206	2.24489642253e-06
ko04925	Aldosterone synthesis and secretion	35/1085	105/7206	2.59471823082e-06
ko05030	Cocaine addiction	27/1085	73/7206	3.14691975953e-06
ko04514	Cell adhesion molecules (CAMs)	40/1085	130/7206	4.89218605381e-06
ko04022	cGMP-PKG signaling pathway	58/1085	216/7206	6.53601089848e-06
ko05164	Influenza A	7/1085	167/7206	9.05039021537e-06
ko04010	MAPK signaling pathway	78/1085	321/7206	9.39050274127e-06
ko04971	Gastric acid secretion	32/1085	98/7206	1.06568288434e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1085	74/7206	1.93825801445e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1085	79/7206	1.95868230685e-05
ko04120	Ubiquitin mediated proteolysis	5/1085	138/7206	1.96653643033e-05
ko05168	Herpes simplex infection	9/1085	182/7206	2.14132071606e-05
ko04141	Protein processing in endoplasmic reticulum	9/1085	184/7206	2.23376399227e-05
ko04745	Phototransduction - fly	16/1085	38/7206	5.22174548837e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1085	79/7206	5.26807757026e-05
ko04014	Ras signaling pathway	65/1085	279/7206	0.000217829849231
ko04064	NF-kappa B signaling pathway	3/1085	96/7206	0.000253514856734
ko04260	Cardiac muscle contraction	29/1085	98/7206	0.000276508746979
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1085	14/7206	0.000331028392487
ko04730	Long-term depression	24/1085	78/7206	0.000359774733671
ko04972	Pancreatic secretion	31/1085	111/7206	0.000416835289075
ko04070	Phosphatidylinositol signaling system	31/1085	112/7206	0.000466740383227
ko04612	Antigen processing and presentation	2/1085	77/7206	0.000610136296378
ko04640	Hematopoietic cell lineage	1/1085	64/7206	0.000625081585967
ko04924	Renin secretion	25/1085	86/7206	0.00072660006179
ko05140	Leishmaniasis	2/1085	75/7206	0.000913098816615
ko05205	Proteoglycans in cancer	23/1085	271/7206	0.00130520806833
ko05161	Hepatitis B	12/1085	173/7206	0.00164820076477
ko00480	Glutathione metabolism	1/1085	55/7206	0.00209757933293
ko04146	Peroxisome	4/1085	89/7206	0.00258177066113
ko04750	Inflammatory mediator regulation of TRP channels	31/1085	122/7206	0.00295503241375
ko05414	Dilated cardiomyopathy	29/1085	112/7206	0.00299060617597
ko04966	Collecting duct acid secretion	10/1085	26/7206	0.00304714682721
ko00590	Arachidonic acid metabolism	1/1085	52/7206	0.00314903256941
ko04371	Apelin signaling pathway	41/1085	177/7206	0.00383669841495
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1085	59/7206	0.00564604580295
ko04540	Gap junction	31/1085	128/7206	0.00572358086598
ko00330	Arginine and proline metabolism	2/1085	61/7206	0.00610524465745
ko04930	Type II diabetes mellitus	16/1085	54/7206	0.00618245276872
ko00240	Pyrimidine metabolism	7/1085	110/7206	0.00698138717864
ko05219	Bladder cancer	1/1085	48/7206	0.00715461470817
ko04711	Circadian rhythm - fly	6/1085	13/7206	0.00762100930224
ko01200	Carbon metabolism	9/1085	128/7206	0.0083719752495
ko04915	Estrogen signaling pathway	31/1085	131/7206	0.00904337202071
ko04110	Cell cycle	11/1085	145/7206	0.00940755991828
ko05169	Epstein-Barr virus infection	18/1085	206/7206	0.00977735652438
ko03022	Basal transcription factors	1/1085	44/7206	0.0104805893577
ko04217	Necroptosis	15/1085	178/7206	0.0105458713678
ko00071	Fatty acid degradation	1/1085	45/7206	0.0105887820274
ko03420	Nucleotide excision repair	1/1085	46/7206	0.0110081169765
ko04072	Phospholipase D signaling pathway	43/1085	197/7206	0.0111112445443
ko05145	Toxoplasmosis	9/1085	126/7206	0.0112718055141
ko04626	Plant-pathogen interaction	7/1085	18/7206	0.0119591811375
ko05110	Vibrio cholerae infection	17/1085	63/7206	0.0124178170152
ko00280	Valine, leucine and isoleucine degradation	2/1085	54/7206	0.0127512237417
ko04630	Jak-STAT signaling pathway	10/1085	132/7206	0.0134797883667
ko03018	RNA degradation	5/1085	84/7206	0.0139852576233
ko01524	Platinum drug resistance	4/1085	76/7206	0.0143786530296
ko04932	Non-alcoholic fatty liver disease (NAFLD)	16/1085	182/7206	0.0153589862104
ko00140	Steroid hormone biosynthesis	1/1085	41/7206	0.0156334448775
ko00983	Drug metabolism - other enzymes	1/1085	42/7206	0.0156811803472
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1085	100/7206	0.0161909600437
ko05131	Shigellosis	5/1085	82/7206	0.0191553380371
ko04622	RIG-I-like receptor signaling pathway	3/1085	62/7206	0.0195631217728
ko04668	TNF signaling pathway	9/1085	120/7206	0.0195963618796
ko05162	Measles	9/1085	120/7206	0.0195963618796
ko04210	Apoptosis	16/1085	180/7206	0.0196235282592
ko04214	Apoptosis - fly	4/1085	72/7206	0.0196768430165
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1085	40/7206	0.0237716935007
ko00380	Tryptophan metabolism	2/1085	50/7206	0.0268953184127
ko03320	PPAR signaling pathway	4/1085	69/7206	0.0272295913541
ko04964	Proximal tubule bicarbonate reclamation	9/1085	29/7206	0.0313337933423
ko04916	Melanogenesis	31/1085	142/7206	0.0318924458851
ko05133	Pertussis	6/1085	87/7206	0.0333916743818
ko00982	Drug metabolism - cytochrome P450	1/1085	37/7206	0.0349552428447
ko00562	Inositol phosphate metabolism	21/1085	89/7206	0.0350657649847
ko00620	Pyruvate metabolism	2/1085	46/7206	0.038061457895
ko05321	Inflammatory bowel disease (IBD)	3/1085	56/7206	0.0386309168947
ko04976	Bile secretion	19/1085	80/7206	0.0392825164518
ko04510	Focal adhesion	25/1085	240/7206	0.0429972576469
ko05215	Prostate cancer	9/1085	111/7206	0.0435502927116
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/1085	26/7206	0.0467234646838
ko04620	Toll-like receptor signaling pathway	8/1085	100/7206	0.0480337015058
ko00310	Lysine degradation	5/1085	73/7206	0.0480444341024
ko04115	p53 signaling pathway	5/1085	74/7206	0.0483717548735