ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	188/1162	423/7206	3.07698752225e-46
ko04724	Glutamatergic synapse	87/1162	152/7206	1.38345250124e-31
ko05033	Nicotine addiction	46/1162	56/7206	1.11832763438e-27
ko05032	Morphine addiction	66/1162	110/7206	8.10895607661e-26
ko04727	GABAergic synapse	65/1162	110/7206	6.53959439598e-25
ko04713	Circadian entrainment	70/1162	136/7206	6.24752636998e-22
ko04721	Synaptic vesicle cycle	50/1162	80/7206	5.99123516053e-21
ko04728	Dopaminergic synapse	80/1162	185/7206	7.17332199023e-19
ko04725	Cholinergic synapse	72/1162	160/7206	2.92575921079e-18
ko04024	cAMP signaling pathway	102/1162	279/7206	2.57900121625e-17
ko04723	Retrograde endocannabinoid signaling	73/1162	175/7206	2.82610307464e-16
ko04020	Calcium signaling pathway	96/1162	265/7206	4.43900661828e-16
ko04744	Phototransduction	26/1162	36/7206	9.55569555518e-14
ko04726	Serotonergic synapse	58/1162	137/7206	1.64615501437e-13
ko04742	Taste transduction	35/1162	61/7206	1.94079848252e-13
ko04921	Oxytocin signaling pathway	76/1162	209/7206	4.81673705254e-13
ko04911	Insulin secretion	51/1162	117/7206	1.26860615033e-12
ko05031	Amphetamine addiction	39/1162	91/7206	1.06675796331e-09
ko04261	Adrenergic signaling in cardiomyocytes	67/1162	205/7206	3.06266236898e-09
ko03040	Spliceosome	2/1162	145/7206	4.09058395992e-09
ko04970	Salivary secretion	39/1162	95/7206	4.76591871411e-09
ko03010	Ribosome	1/1162	129/7206	7.04927044034e-09
ko04720	Long-term potentiation	39/1162	99/7206	1.89669054193e-08
ko04022	cGMP-PKG signaling pathway	64/1162	216/7206	4.27045955515e-07
ko05203	Viral carcinogenesis	17/1162	277/7206	4.40223257541e-07
ko04740	Olfactory transduction	31/1162	80/7206	8.35758010588e-07
ko05322	Systemic lupus erythematosus	5/1162	151/7206	8.85659045115e-07
ko05168	Herpes simplex infection	8/1162	182/7206	1.07518206842e-06
ko04966	Collecting duct acid secretion	15/1162	26/7206	1.5714662868e-06
ko04971	Gastric acid secretion	34/1162	98/7206	5.34598783939e-06
ko04925	Aldosterone synthesis and secretion	36/1162	105/7206	5.35296041677e-06
ko05030	Cocaine addiction	28/1162	73/7206	6.06174840766e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1162	74/7206	6.96543568849e-06
ko04360	Axon guidance	64/1162	233/7206	7.49237557554e-06
ko03013	RNA transport	8/1162	166/7206	9.02301245135e-06
ko05164	Influenza A	8/1162	167/7206	9.16673504826e-06
ko04060	Cytokine-cytokine receptor interaction	11/1162	191/7206	1.49681495884e-05
ko04730	Long-term depression	28/1162	78/7206	1.67257992561e-05
ko04070	Phosphatidylinositol signaling system	36/1162	112/7206	2.26615623739e-05
ko04514	Cell adhesion molecules (CAMs)	40/1162	130/7206	2.97816499376e-05
ko04120	Ubiquitin mediated proteolysis	6/1162	138/7206	3.09715313175e-05
ko04612	Antigen processing and presentation	1/1162	77/7206	3.13295744733e-05
ko04621	NOD-like receptor signaling pathway	8/1162	157/7206	3.72920524518e-05
ko04110	Cell cycle	7/1162	145/7206	4.91775781669e-05
ko04010	MAPK signaling pathway	79/1162	321/7206	6.69290859928e-05
ko04745	Phototransduction - fly	16/1162	38/7206	0.000122063736713
ko04141	Protein processing in endoplasmic reticulum	12/1162	184/7206	0.000144513983059
ko04371	Apelin signaling pathway	48/1162	177/7206	0.000167356087603
ko03008	Ribosome biogenesis in eukaryotes	2/1162	79/7206	0.000173831360937
ko04710	Circadian rhythm	17/1162	43/7206	0.000191053384189
ko05110	Vibrio cholerae infection	22/1162	63/7206	0.000214686614351
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1162	79/7206	0.000280367641917
ko04924	Renin secretion	27/1162	86/7206	0.000340930957799
ko05140	Leishmaniasis	2/1162	75/7206	0.000386018735369
ko04064	NF-kappa B signaling pathway	4/1162	96/7206	0.000406563603151
ko04014	Ras signaling pathway	67/1162	279/7206	0.000467712207607
ko04972	Pancreatic secretion	32/1162	111/7206	0.000627114142073
ko04260	Cardiac muscle contraction	29/1162	98/7206	0.000747442869127
ko04072	Phospholipase D signaling pathway	50/1162	197/7206	0.000761329840933
ko05414	Dilated cardiomyopathy	32/1162	112/7206	0.00101769678847
ko05169	Epstein-Barr virus infection	17/1162	206/7206	0.00103351954566
ko04964	Proximal tubule bicarbonate reclamation	12/1162	29/7206	0.00103817533755
ko04610	Complement and coagulation cascades	3/1162	79/7206	0.00104734264189
ko04750	Inflammatory mediator regulation of TRP channels	34/1162	122/7206	0.00106749958154
ko05161	Hepatitis B	13/1162	173/7206	0.00107988002262
ko04540	Gap junction	35/1162	128/7206	0.00141573273739
ko04976	Bile secretion	24/1162	80/7206	0.00184612137982
ko00590	Arachidonic acid metabolism	1/1162	52/7206	0.00198221701983
ko05162	Measles	8/1162	120/7206	0.00254199976103
ko04923	Regulation of lipolysis in adipocytes	23/1162	77/7206	0.00256375809331
ko04330	Notch signaling pathway	2/1162	62/7206	0.00269412315906
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1162	14/7206	0.00335371424008
ko05205	Proteoglycans in cancer	27/1162	271/7206	0.00406497693392
ko04626	Plant-pathogen interaction	8/1162	18/7206	0.00428047652411
ko05166	HTLV-I infection	30/1162	292/7206	0.00437962414225
ko03420	Nucleotide excision repair	1/1162	46/7206	0.00447575340854
ko05145	Toxoplasmosis	9/1162	126/7206	0.00454267024406
ko04657	IL-17 signaling pathway	5/1162	87/7206	0.00502897154513
ko05321	Inflammatory bowel disease (IBD)	2/1162	56/7206	0.00574293587992
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1162	59/7206	0.0064528959541
ko04350	TGF-beta signaling pathway	7/1162	103/7206	0.00666030603792
ko03022	Basal transcription factors	1/1162	44/7206	0.00669612586025
ko00071	Fatty acid degradation	1/1162	45/7206	0.00685204252176
ko04915	Estrogen signaling pathway	33/1162	131/7206	0.00781232998411
ko00562	Inositol phosphate metabolism	24/1162	89/7206	0.0084358750581
ko00240	Pyrimidine metabolism	8/1162	110/7206	0.00855012467773
ko00480	Glutathione metabolism	2/1162	55/7206	0.00864659145222
ko04922	Glucagon signaling pathway	32/1162	128/7206	0.010237592989
ko04510	Focal adhesion	25/1162	240/7206	0.0123724283138
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1162	100/7206	0.0127738805102
ko04210	Apoptosis	17/1162	180/7206	0.01329938503
ko04622	RIG-I-like receptor signaling pathway	3/1162	62/7206	0.013684914536
ko04930	Type II diabetes mellitus	16/1162	54/7206	0.0138196989357
ko04960	Aldosterone-regulated sodium reabsorption	13/1162	41/7206	0.0163232554852
ko05206	MicroRNAs in cancer	17/1162	177/7206	0.0168013295973
ko05219	Bladder cancer	2/1162	48/7206	0.0177185758308
ko05133	Pertussis	6/1162	87/7206	0.0178410008437
ko05016	Huntington's disease	22/1162	215/7206	0.0181139402238
ko04630	Jak-STAT signaling pathway	12/1162	132/7206	0.0232524194
ko00630	Glyoxylate and dicarboxylate metabolism	1/1162	38/7206	0.0236434076922
ko04146	Peroxisome	7/1162	89/7206	0.0295385211356
ko04217	Necroptosis	18/1162	178/7206	0.0295435753659
ko05131	Shigellosis	6/1162	82/7206	0.0328502587761
ko00860	Porphyrin and chlorophyll metabolism	1/1162	34/7206	0.0334162506503
ko04668	TNF signaling pathway	11/1162	120/7206	0.033501088308
ko04214	Apoptosis - fly	5/1162	72/7206	0.0347777358237
ko04973	Carbohydrate digestion and absorption	12/1162	42/7206	0.0350838113844
ko04658	Th1 and Th2 cell differentiation	8/1162	96/7206	0.0355961136314
ko00280	Valine, leucine and isoleucine degradation	3/1162	54/7206	0.0384905797482
ko05144	Malaria	2/1162	45/7206	0.0386640914016
ko00512	Mucin type O-glycan biosynthesis	9/1162	29/7206	0.0399515481352
ko04711	Circadian rhythm - fly	5/1162	13/7206	0.0449940325829
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/1162	92/7206	0.0458841575659