ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	141/714	423/7206	4.44133375253e-43
ko04724	Glutamatergic synapse	78/714	152/7206	3.46673603829e-39
ko05033	Nicotine addiction	43/714	56/7206	1.13841660462e-32
ko04728	Dopaminergic synapse	74/714	185/7206	3.27046172376e-28
ko04727	GABAergic synapse	56/714	110/7206	4.61452690692e-28
ko05032	Morphine addiction	55/714	110/7206	4.60888348592e-27
ko04713	Circadian entrainment	60/714	136/7206	1.00055344494e-25
ko04723	Retrograde endocannabinoid signaling	65/714	175/7206	9.68454650932e-23
ko04024	cAMP signaling pathway	76/714	279/7206	3.19264399853e-17
ko05031	Amphetamine addiction	39/714	91/7206	1.46374859018e-16
ko04911	Insulin secretion	44/714	117/7206	5.85025849018e-16
ko04020	Calcium signaling pathway	71/714	265/7206	9.97204470515e-16
ko04725	Cholinergic synapse	51/714	160/7206	7.37250438638e-15
ko04726	Serotonergic synapse	46/714	137/7206	1.83890865477e-14
ko04720	Long-term potentiation	38/714	99/7206	2.77188751833e-14
ko04921	Oxytocin signaling pathway	58/714	209/7206	9.52323298089e-14
ko04721	Synaptic vesicle cycle	32/714	80/7206	8.2940935286e-13
ko04261	Adrenergic signaling in cardiomyocytes	55/714	205/7206	1.94269988606e-12
ko05030	Cocaine addiction	29/714	73/7206	1.22276157776e-11
ko04742	Taste transduction	26/714	61/7206	2.13893418532e-11
ko04970	Salivary secretion	33/714	95/7206	3.51067204962e-11
ko04925	Aldosterone synthesis and secretion	32/714	105/7206	3.09141279681e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	25/714	74/7206	1.66150239607e-08
ko04971	Gastric acid secretion	29/714	98/7206	3.56400276478e-08
ko04972	Pancreatic secretion	31/714	111/7206	5.37109908194e-08
ko04060	Cytokine-cytokine receptor interaction	1/714	191/7206	5.64553717182e-08
ko04010	MAPK signaling pathway	63/714	321/7206	8.2192197021e-08
ko04730	Long-term depression	23/714	78/7206	1.00027540179e-06
ko04022	cGMP-PKG signaling pathway	45/714	216/7206	1.16375772127e-06
ko05168	Herpes simplex infection	2/714	182/7206	1.85088614312e-06
ko04070	Phosphatidylinositol signaling system	28/714	112/7206	2.75037879848e-06
ko04915	Estrogen signaling pathway	31/714	131/7206	3.87441716303e-06
ko04740	Olfactory transduction	22/714	80/7206	6.15103097298e-06
ko04924	Renin secretion	23/714	86/7206	6.34986346468e-06
ko03040	Spliceosome	1/714	145/7206	7.39969988597e-06
ko04072	Phospholipase D signaling pathway	40/714	197/7206	8.61316700792e-06
ko04744	Phototransduction	13/714	36/7206	2.11831536344e-05
ko05203	Viral carcinogenesis	9/714	277/7206	3.26516720262e-05
ko04745	Phototransduction - fly	12/714	38/7206	0.000194863473735
ko05034	Alcoholism	42/714	238/7206	0.0002250174398
ko05164	Influenza A	4/714	167/7206	0.000315585429187
ko04540	Gap junction	26/714	128/7206	0.000437093542006
ko04014	Ras signaling pathway	46/714	279/7206	0.000459685795659
ko04260	Cardiac muscle contraction	21/714	98/7206	0.000525032220251
ko05169	Epstein-Barr virus infection	7/714	206/7206	0.000540931550561
ko04621	NOD-like receptor signaling pathway	4/714	157/7206	0.000611096901147
ko04371	Apelin signaling pathway	32/714	177/7206	0.000773445437039
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/714	79/7206	0.000815190799728
ko05322	Systemic lupus erythematosus	4/714	151/7206	0.000854451021682
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/714	182/7206	0.000992544483027
ko04141	Protein processing in endoplasmic reticulum	6/714	184/7206	0.00100444136627
ko04360	Axon guidance	38/714	233/7206	0.00171328589959
ko04750	Inflammatory mediator regulation of TRP channels	23/714	122/7206	0.00203653063222
ko04514	Cell adhesion molecules (CAMs)	24/714	130/7206	0.00259708822246
ko04015	Rap1 signaling pathway	43/714	278/7206	0.00281905033068
ko05414	Dilated cardiomyopathy	21/714	112/7206	0.00361880612785
ko04610	Complement and coagulation cascades	1/714	79/7206	0.00402443151387
ko04110	Cell cycle	5/714	145/7206	0.00478185756199
ko00240	Pyrimidine metabolism	3/714	110/7206	0.00599881887261
ko04626	Plant-pathogen interaction	6/714	18/7206	0.00606199086337
ko04612	Antigen processing and presentation	1/714	77/7206	0.00606809901508
ko05231	Choline metabolism in cancer	23/714	134/7206	0.00797976259411
ko04214	Apoptosis - fly	1/714	72/7206	0.00875107475883
ko04146	Peroxisome	2/714	89/7206	0.0110056158588
ko04140	Autophagy - animal	7/714	164/7206	0.01142566405
ko04550	Signaling pathways regulating pluripotency of stem cells	7/714	165/7206	0.0115246996442
ko03013	RNA transport	7/714	166/7206	0.0116805272779
ko04630	Jak-STAT signaling pathway	5/714	132/7206	0.0122390586992
ko05205	Proteoglycans in cancer	15/714	271/7206	0.0124566604928
ko05162	Measles	4/714	120/7206	0.0125405654745
ko04912	GnRH signaling pathway	21/714	122/7206	0.0131432992955
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/714	59/7206	0.0136951151727
ko04150	mTOR signaling pathway	9/714	184/7206	0.0172610156976
ko00562	Inositol phosphate metabolism	16/714	89/7206	0.0182794667303
ko00600	Sphingolipid metabolism	1/714	63/7206	0.0186292740299
ko04640	Hematopoietic cell lineage	1/714	64/7206	0.0188095168586
ko00512	Mucin type O-glycan biosynthesis	7/714	29/7206	0.0204143117217
ko04964	Proximal tubule bicarbonate reclamation	7/714	29/7206	0.0204143117217
ko03008	Ribosome biogenesis in eukaryotes	2/714	79/7206	0.0218135072815
ko04062	Chemokine signaling pathway	30/714	201/7206	0.0220884440448
ko04064	NF-kappa B signaling pathway	3/714	96/7206	0.0235038640178
ko04142	Lysosome	7/714	151/7206	0.0267021100085
ko04918	Thyroid hormone synthesis	15/714	86/7206	0.0274099185166
ko01212	Fatty acid metabolism	1/714	60/7206	0.0275078173204
ko04510	Focal adhesion	14/714	240/7206	0.0280095366035
ko04622	RIG-I-like receptor signaling pathway	1/714	62/7206	0.0289449294358
ko04120	Ubiquitin mediated proteolysis	6/714	138/7206	0.0293372658102
ko04114	Oocyte meiosis	22/714	139/7206	0.0298593831394
ko05222	Small cell lung cancer	3/714	89/7206	0.031946249198
ko04973	Carbohydrate digestion and absorption	9/714	42/7206	0.0319812923339
ko04916	Melanogenesis	22/714	142/7206	0.0322214681767
ko05214	Glioma	14/714	79/7206	0.0339609253942
ko05202	Transcriptional misregulation in cancer	10/714	188/7206	0.0344152363849
ko04976	Bile secretion	14/714	80/7206	0.0353291302752
ko04966	Collecting duct acid secretion	6/714	26/7206	0.0380538483415
ko05010	Alzheimer's disease	29/714	202/7206	0.0411926419654
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/714	14/7206	0.0427021826587
ko04071	Sphingolipid signaling pathway	24/714	162/7206	0.0446527689615
ko04657	IL-17 signaling pathway	3/714	87/7206	0.0447227598607
ko00310	Lysine degradation	2/714	73/7206	0.0453338853657