ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	164/921	423/7206	7.69852994223e-45
ko05033	Nicotine addiction	46/921	56/7206	2.92638898297e-32
ko04724	Glutamatergic synapse	78/921	152/7206	3.73162524749e-31
ko05032	Morphine addiction	60/921	110/7206	5.00162307164e-26
ko04727	GABAergic synapse	58/921	110/7206	3.52314312321e-24
ko04713	Circadian entrainment	65/921	136/7206	7.52691843511e-24
ko04728	Dopaminergic synapse	75/921	185/7206	7.03462835261e-22
ko04721	Synaptic vesicle cycle	46/921	80/7206	1.69388537242e-21
ko04723	Retrograde endocannabinoid signaling	71/921	175/7206	8.78470209524e-21
ko04725	Cholinergic synapse	64/921	160/7206	1.87702258537e-18
ko04024	cAMP signaling pathway	85/921	279/7206	2.19702984727e-15
ko04911	Insulin secretion	47/921	117/7206	6.06571761142e-14
ko04742	Taste transduction	32/921	61/7206	8.50904624208e-14
ko04726	Serotonergic synapse	51/921	137/7206	1.83992233119e-13
ko04921	Oxytocin signaling pathway	64/921	209/7206	5.08361033829e-12
ko04020	Calcium signaling pathway	73/921	265/7206	5.3523326597e-11
ko05031	Amphetamine addiction	36/921	91/7206	9.38268946153e-11
ko04261	Adrenergic signaling in cardiomyocytes	60/921	205/7206	1.9444848055e-10
ko04720	Long-term potentiation	36/921	99/7206	1.48942353494e-09
ko04744	Phototransduction	19/921	36/7206	8.96923510235e-09
ko03040	Spliceosome	1/921	145/7206	9.2673605475e-08
ko04970	Salivary secretion	32/921	95/7206	9.9822172017e-08
ko04925	Aldosterone synthesis and secretion	34/921	105/7206	1.19353247046e-07
ko05203	Viral carcinogenesis	10/921	277/7206	1.75729712763e-07
ko04514	Cell adhesion molecules (CAMs)	38/921	130/7206	4.5149474272e-07
ko05168	Herpes simplex infection	4/921	182/7206	4.56784126711e-07
ko05030	Cocaine addiction	26/921	73/7206	4.60252141395e-07
ko04060	Cytokine-cytokine receptor interaction	5/921	191/7206	1.38412154782e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/921	74/7206	2.35465663383e-06
ko05164	Influenza A	4/921	167/7206	3.05185503044e-06
ko04740	Olfactory transduction	26/921	80/7206	3.39064791876e-06
ko04966	Collecting duct acid secretion	13/921	26/7206	4.66590486875e-06
ko04971	Gastric acid secretion	29/921	98/7206	9.10007604347e-06
ko04120	Ubiquitin mediated proteolysis	3/921	138/7206	1.47484297198e-05
ko05322	Systemic lupus erythematosus	4/921	151/7206	1.97525594585e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/921	79/7206	4.78784493343e-05
ko04010	MAPK signaling pathway	66/921	321/7206	7.24784476541e-05
ko04260	Cardiac muscle contraction	27/921	98/7206	8.55727217979e-05
ko04972	Pancreatic secretion	29/921	111/7206	0.000134236754885
ko04745	Phototransduction - fly	14/921	38/7206	0.000139010328399
ko05110	Vibrio cholerae infection	19/921	63/7206	0.000214190129467
ko04621	NOD-like receptor signaling pathway	6/921	157/7206	0.000231452354177
ko04360	Axon guidance	49/921	233/7206	0.000304913337592
ko03013	RNA transport	7/921	166/7206	0.000345724944809
ko04022	cGMP-PKG signaling pathway	46/921	216/7206	0.000383914737056
ko04141	Protein processing in endoplasmic reticulum	9/921	184/7206	0.000469815344246
ko04612	Antigen processing and presentation	1/921	77/7206	0.000481454169108
ko05205	Proteoglycans in cancer	17/921	271/7206	0.000556042925986
ko05169	Epstein-Barr virus infection	11/921	206/7206	0.000621012856319
ko04072	Phospholipase D signaling pathway	42/921	197/7206	0.000704924944809
ko05162	Measles	4/921	120/7206	0.000758161015796
ko04730	Long-term depression	21/921	78/7206	0.000847498207252
ko05161	Hepatitis B	9/921	173/7206	0.00117995901029
ko04140	Autophagy - animal	8/921	164/7206	0.00123289738264
ko04915	Estrogen signaling pathway	30/921	131/7206	0.00129926808493
ko04064	NF-kappa B signaling pathway	3/921	96/7206	0.00183432465581
ko05166	HTLV-I infection	21/921	292/7206	0.00228855052706
ko04110	Cell cycle	7/921	145/7206	0.00229562831293
ko05414	Dilated cardiomyopathy	26/921	112/7206	0.00233286386772
ko04070	Phosphatidylinositol signaling system	26/921	112/7206	0.00233286386772
ko04610	Complement and coagulation cascades	2/921	79/7206	0.0032911002415
ko03008	Ribosome biogenesis in eukaryotes	2/921	79/7206	0.0032911002415
ko04330	Notch signaling pathway	1/921	62/7206	0.00353372069442
ko04750	Inflammatory mediator regulation of TRP channels	27/921	122/7206	0.00368151440743
ko04014	Ras signaling pathway	52/921	279/7206	0.00440429709147
ko05140	Leishmaniasis	2/921	75/7206	0.00467058367006
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/921	14/7206	0.00517424181345
ko05215	Prostate cancer	5/921	111/7206	0.00591519417831
ko04976	Bile secretion	19/921	80/7206	0.0062487217967
ko04214	Apoptosis - fly	2/921	72/7206	0.00679145645613
ko04540	Gap junction	27/921	128/7206	0.00718633183495
ko00480	Glutathione metabolism	1/921	55/7206	0.0077482872848
ko04964	Proximal tubule bicarbonate reclamation	9/921	29/7206	0.00807853897595
ko04924	Renin secretion	20/921	86/7206	0.00817389832628
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/921	182/7206	0.00932716693542
ko04217	Necroptosis	12/921	178/7206	0.012061400839
ko04146	Peroxisome	4/921	89/7206	0.0154842181323
ko05016	Huntington's disease	16/921	215/7206	0.0165706141479
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/921	92/7206	0.0169164703784
ko04630	Jak-STAT signaling pathway	8/921	132/7206	0.0172229119133
ko04550	Signaling pathways regulating pluripotency of stem cells	11/921	165/7206	0.0175296876122
ko04626	Plant-pathogen interaction	6/921	18/7206	0.0204188849908
ko00310	Lysine degradation	3/921	73/7206	0.0211081286465
ko04930	Type II diabetes mellitus	13/921	54/7206	0.0217033616258
ko04657	IL-17 signaling pathway	4/921	87/7206	0.0219696761981
ko05410	Hypertrophic cardiomyopathy (HCM)	21/921	100/7206	0.0221151878796
ko04510	Focal adhesion	19/921	240/7206	0.0231221426461
ko05144	Malaria	1/921	45/7206	0.0249866800542
ko00071	Fatty acid degradation	1/921	45/7206	0.0249866800542
ko03420	Nucleotide excision repair	1/921	46/7206	0.0250227573154
ko05200	Pathways in cancer	47/921	492/7206	0.0251337694403
ko04912	GnRH signaling pathway	24/921	122/7206	0.0278773409238
ko05206	MicroRNAs in cancer	13/921	177/7206	0.0295125409748
ko04350	TGF-beta signaling pathway	6/921	103/7206	0.0358322019597
ko04371	Apelin signaling pathway	32/921	177/7206	0.0395162889833
ko00280	Valine, leucine and isoleucine degradation	2/921	54/7206	0.0405247701702
ko04210	Apoptosis	14/921	180/7206	0.0414749264319
ko05321	Inflammatory bowel disease (IBD)	2/921	56/7206	0.04147929809
ko05217	Basal cell carcinoma	3/921	68/7206	0.0420834751262
ko00240	Pyrimidine metabolism	7/921	110/7206	0.0429742955488
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/921	59/7206	0.0469344583233