ko pathway ratio_in_study ratio_in_pop p_value ko05322 Systemic lupus erythematosus 48/181 151/7206 2.02337223452e-41 ko05034 Alcoholism 47/181 238/7206 4.28968005119e-30 ko05203 Viral carcinogenesis 36/181 277/7206 1.07449966998e-16 ko04110 Cell cycle 26/181 145/7206 1.15187622213e-15 ko04111 Cell cycle - yeast 19/181 90/7206 4.70898084899e-13 ko04113 Meiosis - yeast 13/181 70/7206 1.40067617641e-08 ko03440 Homologous recombination 9/181 41/7206 5.71577376085e-07 ko03040 Spliceosome 16/181 145/7206 5.91410393123e-07 ko05202 Transcriptional misregulation in cancer 18/181 188/7206 9.57259669877e-07 ko04114 Oocyte meiosis 15/181 139/7206 1.79914432426e-06 ko04217 Necroptosis 16/181 178/7206 8.9811809994e-06 ko03030 DNA replication 7/181 38/7206 3.66828316252e-05 ko03460 Fanconi anemia pathway 7/181 51/7206 0.000255532374986 ko04914 Progesterone-mediated oocyte maturation 10/181 104/7206 0.000263661538668 ko00240 Pyrimidine metabolism 9/181 110/7206 0.00171186066285 ko03410 Base excision repair 5/181 38/7206 0.00242368262357 ko04024 cAMP signaling pathway 1/181 279/7206 0.010392656928 ko04015 Rap1 signaling pathway 1/181 278/7206 0.010394029312 ko04115 p53 signaling pathway 6/181 74/7206 0.0104287469834 ko04810 Regulation of actin cytoskeleton 1/181 264/7206 0.0150878883395 ko03430 Mismatch repair 3/181 22/7206 0.0168931587367 ko04151 PI3K-Akt signaling pathway 3/181 390/7206 0.0186756388891 ko03420 Nucleotide excision repair 4/181 46/7206 0.0276762125804 ko04510 Focal adhesion 1/181 240/7206 0.0323602252874 ko04218 Cellular senescence 9/181 177/7206 0.0443891730378 ko04530 Tight junction 1/181 228/7206 0.0477545329237 ko04014 Ras signaling pathway 2/181 279/7206 0.0490873528454