ko pathway ratio_in_study ratio_in_pop p_value ko05322 Systemic lupus erythematosus 72/250 151/7206 2.83876680801e-67 ko05034 Alcoholism 72/250 238/7206 2.55870445318e-50 ko05203 Viral carcinogenesis 56/250 277/7206 1.41267449117e-28 ko03040 Spliceosome 26/250 145/7206 2.82046093437e-12 ko04111 Cell cycle - yeast 20/250 90/7206 1.74513417902e-11 ko04110 Cell cycle 25/250 145/7206 1.87299348563e-11 ko04113 Meiosis - yeast 13/250 70/7206 6.28430157262e-07 ko03008 Ribosome biogenesis in eukaryotes 13/250 79/7206 2.6443524301e-06 ko04217 Necroptosis 20/250 178/7206 3.06041721563e-06 ko03013 RNA transport 19/250 166/7206 4.13769019198e-06 ko05202 Transcriptional misregulation in cancer 19/250 188/7206 2.52566017709e-05 ko04114 Oocyte meiosis 15/250 139/7206 8.68022397149e-05 ko04144 Endocytosis 1/250 342/7206 0.000106983639691 ko04914 Progesterone-mediated oocyte maturation 10/250 104/7206 0.00313557108628 ko04024 cAMP signaling pathway 2/250 279/7206 0.00651790805712 ko03018 RNA degradation 8/250 84/7206 0.00840774124853 ko04810 Regulation of actin cytoskeleton 2/250 264/7206 0.00903417959612 ko04151 PI3K-Akt signaling pathway 5/250 390/7206 0.0101206957739 ko04921 Oxytocin signaling pathway 1/250 209/7206 0.0108100961429 ko03440 Homologous recombination 5/250 41/7206 0.0130494928642 ko04072 Phospholipase D signaling pathway 1/250 197/7206 0.0155708576892 ko04510 Focal adhesion 2/250 240/7206 0.0180193462627 ko04015 Rap1 signaling pathway 3/250 278/7206 0.0189423310772 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/250 182/7206 0.021984732111 ko05152 Tuberculosis 1/250 187/7206 0.0227949750838 ko04530 Tight junction 2/250 228/7206 0.0253311910356 ko04120 Ubiquitin mediated proteolysis 10/250 138/7206 0.0286937481413 ko05166 HTLV-I infection 17/250 292/7206 0.0325967206784 ko05016 Huntington's disease 2/250 215/7206 0.0353525661227 ko05200 Pathways in cancer 9/250 492/7206 0.0401269208757 ko03030 DNA replication 4/250 38/7206 0.041467457786 ko03015 mRNA surveillance pathway 7/250 93/7206 0.0421347432429 ko05012 Parkinson's disease 1/250 155/7206 0.0451459795637 ko04725 Cholinergic synapse 1/250 160/7206 0.045771604804 ko04611 Platelet activation 1/250 163/7206 0.0467355980944