ko pathway ratio_in_study ratio_in_pop p_value ko05322 Systemic lupus erythematosus 69/272 151/7206 7.02160849422e-60 ko05034 Alcoholism 70/272 238/7206 3.75311649244e-45 ko05203 Viral carcinogenesis 56/272 277/7206 1.41819358554e-26 ko04111 Cell cycle - yeast 22/272 90/7206 1.12465966927e-12 ko04110 Cell cycle 26/272 145/7206 1.96705127321e-11 ko03440 Homologous recombination 11/272 41/7206 2.08826169407e-07 ko04113 Meiosis - yeast 14/272 70/7206 2.47021183357e-07 ko05202 Transcriptional misregulation in cancer 23/272 188/7206 5.22365698789e-07 ko04217 Necroptosis 20/272 178/7206 1.0986480335e-05 ko04144 Endocytosis 1/272 342/7206 3.29904436918e-05 ko03030 DNA replication 8/272 38/7206 6.77808094549e-05 ko03460 Fanconi anemia pathway 9/272 51/7206 0.000102869268399 ko03040 Spliceosome 16/272 145/7206 0.000105254369238 ko04151 PI3K-Akt signaling pathway 3/272 390/7206 0.00030894712979 ko04024 cAMP signaling pathway 1/272 279/7206 0.000344342452888 ko03410 Base excision repair 7/272 38/7206 0.000466477572868 ko04114 Oocyte meiosis 14/272 139/7206 0.000723961945361 ko04020 Calcium signaling pathway 1/272 265/7206 0.000764211956314 ko03430 Mismatch repair 5/272 22/7206 0.00114622035473 ko03008 Ribosome biogenesis in eukaryotes 9/272 79/7206 0.00276873634137 ko05205 Proteoglycans in cancer 2/272 271/7206 0.00308205546436 ko03018 RNA degradation 9/272 84/7206 0.00420519000441 ko04810 Regulation of actin cytoskeleton 2/272 264/7206 0.00446225028306 ko03013 RNA transport 14/272 166/7206 0.00548342768232 ko04072 Phospholipase D signaling pathway 1/272 197/7206 0.00718185128742 ko05010 Alzheimer's disease 1/272 202/7206 0.00738846280128 ko04261 Adrenergic signaling in cardiomyocytes 1/272 205/7206 0.00765337667385 ko00240 Pyrimidine metabolism 10/272 110/7206 0.00839503835992 ko04510 Focal adhesion 2/272 240/7206 0.00892279564335 ko04014 Ras signaling pathway 3/272 279/7206 0.0098310650336 ko04015 Rap1 signaling pathway 3/272 278/7206 0.00983198422035 ko04728 Dopaminergic synapse 1/272 185/7206 0.0104049850798 ko05152 Tuberculosis 1/272 187/7206 0.0104282404102 ko04060 Cytokine-cytokine receptor interaction 1/272 191/7206 0.0106687447509 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/272 182/7206 0.0156706226727 ko04914 Progesterone-mediated oocyte maturation 9/272 104/7206 0.0163718304997 ko05164 Influenza A 1/272 167/7206 0.0218865043001 ko03022 Basal transcription factors 5/272 44/7206 0.0241059521145 ko04712 Circadian rhythm - plant 2/272 7/7206 0.0262923984132 ko05160 Hepatitis C 1/272 153/7206 0.0313164596042 ko05012 Parkinson's disease 1/272 155/7206 0.0313857991742 ko04621 NOD-like receptor signaling pathway 1/272 157/7206 0.0316267375449 ko04010 MAPK signaling pathway 5/272 321/7206 0.0341163704764 ko04062 Chemokine signaling pathway 2/272 201/7206 0.0359531061681