ko pathway ratio_in_study ratio_in_pop p_value ko05322 Systemic lupus erythematosus 65/268 151/7206 1.24107735646e-54 ko05034 Alcoholism 65/268 238/7206 5.42057161962e-40 ko05203 Viral carcinogenesis 51/268 277/7206 1.57009893796e-22 ko04110 Cell cycle 28/268 145/7206 3.21259870454e-13 ko04111 Cell cycle - yeast 22/268 90/7206 8.31600074701e-13 ko03040 Spliceosome 25/268 145/7206 8.60888010595e-11 ko03440 Homologous recombination 11/268 41/7206 1.79676265615e-07 ko04113 Meiosis - yeast 13/268 70/7206 1.38425137493e-06 ko05202 Transcriptional misregulation in cancer 22/268 188/7206 1.55601177675e-06 ko03030 DNA replication 9/268 38/7206 7.51753349083e-06 ko03430 Mismatch repair 7/268 22/7206 9.60472514324e-06 ko04144 Endocytosis 1/268 342/7206 4.95899122526e-05 ko04114 Oocyte meiosis 16/268 139/7206 5.28512539224e-05 ko04217 Necroptosis 18/268 178/7206 0.000101751587122 ko03013 RNA transport 17/268 166/7206 0.000135812507185 ko03410 Base excision repair 7/268 38/7206 0.000426518413658 ko04151 PI3K-Akt signaling pathway 3/268 390/7206 0.000456459156266 ko04014 Ras signaling pathway 1/268 279/7206 0.000517448087605 ko03460 Fanconi anemia pathway 8/268 51/7206 0.000522619006115 ko04914 Progesterone-mediated oocyte maturation 11/268 104/7206 0.00158881940581 ko04360 Axon guidance 1/268 233/7206 0.0023341976371 ko00240 Pyrimidine metabolism 11/268 110/7206 0.00249562214424 ko03008 Ribosome biogenesis in eukaryotes 9/268 79/7206 0.00250510111642 ko04010 MAPK signaling pathway 3/268 321/7206 0.00362970278287 ko05166 HTLV-I infection 21/268 292/7206 0.00376975197771 ko04022 cGMP-PKG signaling pathway 1/268 216/7206 0.0051031222332 ko03420 Nucleotide excision repair 6/268 46/7206 0.00671175148961 ko04261 Adrenergic signaling in cardiomyocytes 1/268 205/7206 0.00739176287945 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/268 191/7206 0.0104794098346 ko03018 RNA degradation 8/268 84/7206 0.0124849276483 ko05205 Proteoglycans in cancer 3/268 271/7206 0.0136711580999 ko04371 Apelin signaling pathway 1/268 177/7206 0.0150663739402 ko04210 Apoptosis 1/268 180/7206 0.0151499284562 ko04728 Dopaminergic synapse 1/268 185/7206 0.0157281038876 ko00310 Lysine degradation 7/268 73/7206 0.0183005390554 ko04530 Tight junction 2/268 228/7206 0.0185682701468 ko04910 Insulin signaling pathway 1/268 172/7206 0.0222334030184 ko03022 Basal transcription factors 5/268 44/7206 0.0227769573083 ko04621 NOD-like receptor signaling pathway 1/268 157/7206 0.031384590429 ko04071 Sphingolipid signaling pathway 1/268 162/7206 0.0322211499626 ko04611 Platelet activation 1/268 163/7206 0.0325130895265 ko04140 Autophagy - animal 1/268 164/7206 0.0328465696501 ko04120 Ubiquitin mediated proteolysis 10/268 138/7206 0.037636570386 ko05217 Basal cell carcinoma 6/268 68/7206 0.0400080541157 ko04142 Lysosome 1/268 151/7206 0.0462087748583 ko05160 Hepatitis C 1/268 153/7206 0.0470498261172 ko04270 Vascular smooth muscle contraction 1/268 154/7206 0.0475540486712