ko pathway ratio_in_study ratio_in_pop p_value ko05322 Systemic lupus erythematosus 66/266 151/7206 2.78137220796e-56 ko05034 Alcoholism 66/266 238/7206 2.53573636466e-41 ko05203 Viral carcinogenesis 50/266 277/7206 7.69794359755e-22 ko04110 Cell cycle 28/266 145/7206 2.66060121426e-13 ko04111 Cell cycle - yeast 20/266 90/7206 5.43361641322e-11 ko03040 Spliceosome 22/266 145/7206 1.27007523316e-08 ko04113 Meiosis - yeast 13/266 70/7206 1.27203854831e-06 ko05202 Transcriptional misregulation in cancer 22/266 188/7206 1.37168991559e-06 ko03440 Homologous recombination 10/266 41/7206 1.61577620165e-06 ko04217 Necroptosis 21/266 178/7206 2.10636972157e-06 ko03013 RNA transport 18/266 166/7206 3.66895002657e-05 ko04114 Oocyte meiosis 16/266 139/7206 4.82822258183e-05 ko04144 Endocytosis 1/266 342/7206 4.88646952128e-05 ko03460 Fanconi anemia pathway 8/266 51/7206 0.000497157095185 ko04015 Rap1 signaling pathway 1/266 278/7206 0.000507291942399 ko04024 cAMP signaling pathway 1/266 279/7206 0.000509582924849 ko03008 Ribosome biogenesis in eukaryotes 10/266 79/7206 0.000602577575813 ko04810 Regulation of actin cytoskeleton 1/266 264/7206 0.000743197296082 ko04151 PI3K-Akt signaling pathway 4/266 390/7206 0.00204700836961 ko04510 Focal adhesion 1/266 240/7206 0.00242737708161 ko04014 Ras signaling pathway 2/266 279/7206 0.00309561727015 ko05205 Proteoglycans in cancer 2/266 271/7206 0.00449393511145 ko04914 Progesterone-mediated oocyte maturation 10/266 104/7206 0.00487134747765 ko04115 p53 signaling pathway 8/266 74/7206 0.00567043299758 ko04062 Chemokine signaling pathway 1/266 201/7206 0.00718402589376 ko03430 Mismatch repair 4/266 22/7206 0.00785153626714 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/266 191/7206 0.0104326222554 ko04060 Cytokine-cytokine receptor interaction 1/266 191/7206 0.0104326222554 ko03018 RNA degradation 8/266 84/7206 0.0119712576801 ko03030 DNA replication 5/266 38/7206 0.0122235299659 ko03410 Base excision repair 5/266 38/7206 0.0122235299659 ko04010 MAPK signaling pathway 4/266 321/7206 0.0142121369322 ko04210 Apoptosis 1/266 180/7206 0.0150930198913 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/266 182/7206 0.0151981119386 ko05152 Tuberculosis 1/266 187/7206 0.0158402362894 ko05166 HTLV-I infection 19/266 292/7206 0.0159717444355 ko04530 Tight junction 2/266 228/7206 0.0182955574559 ko05164 Influenza A 1/266 167/7206 0.021766390334 ko04910 Insulin signaling pathway 1/266 172/7206 0.022046357414 ko04621 NOD-like receptor signaling pathway 1/266 157/7206 0.0313490948671 ko04722 Neurotrophin signaling pathway 1/266 160/7206 0.0315768284673 ko04152 AMPK signaling pathway 1/266 161/7206 0.0317347245077 ko04071 Sphingolipid signaling pathway 1/266 162/7206 0.0319335517443 ko04120 Ubiquitin mediated proteolysis 10/266 138/7206 0.0364365776143 ko04670 Leukocyte transendothelial migration 1/266 151/7206 0.0458472524999 ko05012 Parkinson's disease 1/266 155/7206 0.0474848722023 ko04360 Axon guidance 3/266 233/7206 0.049663222212