ko pathway ratio_in_study ratio_in_pop p_value ko05033 Nicotine addiction 8/63 56/7206 2.2076671841e-08 ko04721 Synaptic vesicle cycle 7/63 80/7206 5.34741236901e-06 ko04723 Retrograde endocannabinoid signaling 9/63 175/7206 1.83229191609e-05 ko04728 Dopaminergic synapse 8/63 185/7206 0.000187738011797 ko04727 GABAergic synapse 6/63 110/7206 0.000369793562261 ko04024 cAMP signaling pathway 9/63 279/7206 0.000647378758852 ko04713 Circadian entrainment 6/63 136/7206 0.00113750459771 ko04724 Glutamatergic synapse 6/63 152/7206 0.00201325191587 ko05032 Morphine addiction 5/63 110/7206 0.00263168227254 ko04080 Neuroactive ligand-receptor interaction 10/63 423/7206 0.00338125845246 ko04911 Insulin secretion 5/63 117/7206 0.0034384388313 ko00604 Glycosphingolipid biosynthesis - ganglio series 2/63 14/7206 0.00639796792323 ko04020 Calcium signaling pathway 7/63 265/7206 0.00800377741592 ko05031 Amphetamine addiction 4/63 91/7206 0.00803852877445 ko05030 Cocaine addiction 3/63 73/7206 0.0256776030733 ko05014 Amyotrophic lateral sclerosis (ALS) 3/63 74/7206 0.02659930893 ko04014 Ras signaling pathway 6/63 279/7206 0.0342617723948 ko04970 Salivary secretion 3/63 95/7206 0.0499739788446