ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 21/249 145/7206 2.00147414658e-08 ko05217 Basal cell carcinoma 12/249 68/7206 2.89633424896e-06 ko05200 Pathways in cancer 37/249 492/7206 8.04196609185e-06 ko03040 Spliceosome 17/249 145/7206 9.24601182015e-06 ko04080 Neuroactive ligand-receptor interaction 2/249 423/7206 5.20144760175e-05 ko03013 RNA transport 17/249 166/7206 5.46417066378e-05 ko04111 Cell cycle - yeast 12/249 90/7206 5.5448244e-05 ko05224 Breast cancer 17/249 174/7206 9.88441275691e-05 ko04390 Hippo signaling pathway 17/249 188/7206 0.000254134369412 ko03030 DNA replication 7/249 38/7206 0.000272483250127 ko05206 MicroRNAs in cancer 16/249 177/7206 0.000387140654306 ko04310 Wnt signaling pathway 15/249 181/7206 0.0014381264848 ko05205 Proteoglycans in cancer 20/249 271/7206 0.00173131049344 ko03018 RNA degradation 9/249 84/7206 0.00232949432532 ko04360 Axon guidance 17/249 233/7206 0.00305810183063 ko04919 Thyroid hormone signaling pathway 12/249 143/7206 0.00381447673798 ko04392 Hippo signaling pathway -multiple species 5/249 31/7206 0.00385009332602 ko05215 Prostate cancer 10/249 111/7206 0.00487476337629 ko04550 Signaling pathways regulating pluripotency of stem cells 13/249 165/7206 0.00737332950713 ko05166 HTLV-I infection 19/249 292/7206 0.00775120516819 ko03410 Base excision repair 5/249 38/7206 0.00935080276454 ko04261 Adrenergic signaling in cardiomyocytes 1/249 205/7206 0.0104819891028 ko05222 Small cell lung cancer 8/249 89/7206 0.0114913521434 ko04391 Hippo signaling pathway - fly 8/249 90/7206 0.0122479568487 ko04340 Hedgehog signaling pathway 6/249 58/7206 0.0144397295651 ko04530 Tight junction 15/249 228/7206 0.0150415317889 ko05034 Alcoholism 2/249 238/7206 0.0178357148474 ko03008 Ribosome biogenesis in eukaryotes 7/249 79/7206 0.0189225907845 ko04330 Notch signaling pathway 6/249 62/7206 0.0195773531105 ko04217 Necroptosis 1/249 178/7206 0.0218283393164 ko04728 Dopaminergic synapse 1/249 185/7206 0.0222715013746 ko05212 Pancreatic cancer 7/249 83/7206 0.0241539779302 ko05219 Bladder cancer 5/249 48/7206 0.0241677144342 ko04350 TGF-beta signaling pathway 8/249 103/7206 0.0256943863132 ko04520 Adherens junction 8/249 103/7206 0.0256943863132 ko05218 Melanoma 7/249 85/7206 0.0271103574143 ko05216 Thyroid cancer 4/249 34/7206 0.0286158852611 ko04723 Retrograde endocannabinoid signaling 1/249 175/7206 0.0324727467982 ko04113 Meiosis - yeast 6/249 70/7206 0.0333088304583 ko04011 MAPK signaling pathway - yeast 5/249 53/7206 0.0352911796135 ko04020 Calcium signaling pathway 3/249 265/7206 0.0370470292745 ko04139 Mitophagy - yeast 4/249 37/7206 0.0376291932043 ko05416 Viral myocarditis 5/249 55/7206 0.0404961889177 ko04621 NOD-like receptor signaling pathway 1/249 157/7206 0.0452005834049 ko04725 Cholinergic synapse 1/249 160/7206 0.0456285132745 ko04152 AMPK signaling pathway 1/249 161/7206 0.0458686268888 ko04140 Autophagy - animal 1/249 164/7206 0.0468796352835 ko05211 Renal cell carcinoma 7/249 96/7206 0.0477864660113 ko05130 Pathogenic Escherichia coli infection 6/249 77/7206 0.0494843051688