ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	68/716	152/7206	1.93974958387e-29
ko04080	Neuroactive ligand-receptor interaction	116/716	423/7206	2.59102604195e-26
ko04713	Circadian entrainment	56/716	136/7206	3.29363832749e-22
ko05033	Nicotine addiction	33/716	56/7206	1.40105178629e-19
ko04727	GABAergic synapse	44/716	110/7206	4.20272352449e-17
ko05032	Morphine addiction	44/716	110/7206	4.20272352449e-17
ko04728	Dopaminergic synapse	59/716	185/7206	5.6164264466e-17
ko04020	Calcium signaling pathway	72/716	265/7206	3.17216570528e-16
ko04720	Long-term potentiation	38/716	99/7206	3.03563731986e-14
ko04911	Insulin secretion	41/716	117/7206	1.08218680172e-13
ko04723	Retrograde endocannabinoid signaling	51/716	175/7206	4.43834882609e-13
ko04024	cAMP signaling pathway	68/716	279/7206	8.37387769873e-13
ko05031	Amphetamine addiction	33/716	91/7206	9.789443222e-12
ko04726	Serotonergic synapse	41/716	137/7206	3.7315885459e-11
ko04921	Oxytocin signaling pathway	53/716	209/7206	5.82159778825e-11
ko04725	Cholinergic synapse	44/716	160/7206	1.57450651818e-10
ko04721	Synaptic vesicle cycle	29/716	80/7206	1.82304738709e-10
ko04261	Adrenergic signaling in cardiomyocytes	51/716	205/7206	2.86754212627e-10
ko04970	Salivary secretion	31/716	95/7206	8.956739891e-10
ko05030	Cocaine addiction	25/716	73/7206	1.28285423258e-08
ko04745	Phototransduction - fly	17/716	38/7206	2.88590172578e-08
ko04925	Aldosterone synthesis and secretion	30/716	105/7206	5.34544569003e-08
ko04730	Long-term depression	25/716	78/7206	5.81553640292e-08
ko04744	Phototransduction	16/716	36/7206	8.32695259799e-08
ko04971	Gastric acid secretion	28/716	98/7206	1.49050888366e-07
ko04742	Taste transduction	21/716	61/7206	1.70538528737e-07
ko04022	cGMP-PKG signaling pathway	46/716	216/7206	3.9206724982e-07
ko04740	Olfactory transduction	24/716	80/7206	4.30641165275e-07
ko04070	Phosphatidylinositol signaling system	29/716	112/7206	8.86518024505e-07
ko05168	Herpes simplex infection	2/716	182/7206	1.86327860172e-06
ko03040	Spliceosome	1/716	145/7206	7.45369891639e-06
ko04750	Inflammatory mediator regulation of TRP channels	29/716	122/7206	8.2828133031e-06
ko03010	Ribosome	1/716	129/7206	3.69136342927e-05
ko04060	Cytokine-cytokine receptor interaction	4/716	191/7206	3.69839128978e-05
ko04924	Renin secretion	21/716	86/7206	7.27737466383e-05
ko04972	Pancreatic secretion	25/716	111/7206	7.41132605616e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/716	74/7206	7.69408503008e-05
ko04010	MAPK signaling pathway	54/716	321/7206	8.1152517793e-05
ko04260	Cardiac muscle contraction	23/716	98/7206	9.78527445727e-05
ko04514	Cell adhesion molecules (CAMs)	27/716	130/7206	0.000165887484765
ko05203	Viral carcinogenesis	11/716	277/7206	0.000293973924413
ko04964	Proximal tubule bicarbonate reclamation	10/716	29/7206	0.000304653499857
ko04922	Glucagon signaling pathway	26/716	128/7206	0.000443992577788
ko04540	Gap junction	26/716	128/7206	0.000443992577788
ko05169	Epstein-Barr virus infection	7/716	206/7206	0.00054069150714
ko05162	Measles	2/716	120/7206	0.000575639387708
ko04072	Phospholipase D signaling pathway	35/716	197/7206	0.000613629464284
ko05322	Systemic lupus erythematosus	4/716	151/7206	0.000852891198468
ko05164	Influenza A	5/716	167/7206	0.000939787784383
ko04141	Protein processing in endoplasmic reticulum	6/716	184/7206	0.00101076988032
ko04630	Jak-STAT signaling pathway	3/716	132/7206	0.00104843479014
ko04626	Plant-pathogen interaction	7/716	18/7206	0.00110799344351
ko04114	Oocyte meiosis	26/716	139/7206	0.0013814931011
ko04110	Cell cycle	4/716	145/7206	0.00173198793065
ko05214	Glioma	17/716	79/7206	0.00186072528894
ko04360	Axon guidance	38/716	233/7206	0.00240908357248
ko04621	NOD-like receptor signaling pathway	5/716	157/7206	0.00261704288177
ko05034	Alcoholism	38/716	238/7206	0.00278693927439
ko04510	Focal adhesion	11/716	240/7206	0.00290764962669
ko04014	Ras signaling pathway	43/716	279/7206	0.00297930128884
ko00562	Inositol phosphate metabolism	18/716	89/7206	0.00342208784378
ko03013	RNA transport	6/716	166/7206	0.00354218392842
ko04064	NF-kappa B signaling pathway	2/716	96/7206	0.00526604459258
ko04960	Aldosterone-regulated sodium reabsorption	10/716	41/7206	0.00569480015391
ko05130	Pathogenic Escherichia coli infection	1/716	77/7206	0.00609483917235
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/716	59/7206	0.00648955907156
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/716	182/7206	0.00809099098488
ko05010	Alzheimer's disease	32/716	202/7206	0.00810354811878
ko04915	Estrogen signaling pathway	22/716	131/7206	0.0119030203081
ko05200	Pathways in cancer	33/716	492/7206	0.0122622059764
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/716	79/7206	0.0124414351158
ko05202	Transcriptional misregulation in cancer	9/716	188/7206	0.01318067619
ko04912	GnRH signaling pathway	21/716	122/7206	0.0132679670148
ko05161	Hepatitis B	8/716	173/7206	0.0141918879293
ko04012	ErbB signaling pathway	19/716	109/7206	0.0142455524096
ko04978	Mineral absorption	9/716	40/7206	0.014644084625
ko04371	Apelin signaling pathway	28/716	177/7206	0.0147202572646
ko00680	Methane metabolism	8/716	34/7206	0.0160350245863
ko04918	Thyroid hormone synthesis	16/716	86/7206	0.0162766692368
ko05414	Dilated cardiomyopathy	19/716	112/7206	0.0167745259956
ko04330	Notch signaling pathway	1/716	62/7206	0.0186177392312
ko04610	Complement and coagulation cascades	2/716	79/7206	0.0218321071892
ko03008	Ribosome biogenesis in eukaryotes	2/716	79/7206	0.0218321071892
ko00240	Pyrimidine metabolism	4/716	110/7206	0.0232578038585
ko04668	TNF signaling pathway	5/716	120/7206	0.0303103794512
ko05222	Small cell lung cancer	3/716	89/7206	0.0319166641982
ko04973	Carbohydrate digestion and absorption	9/716	42/7206	0.0321519003072
ko04711	Circadian rhythm - fly	4/716	13/7206	0.0333206409281
ko04966	Collecting duct acid secretion	6/716	26/7206	0.0385084805353
ko05416	Viral myocarditis	1/716	55/7206	0.0397070458635
ko04270	Vascular smooth muscle contraction	23/716	154/7206	0.0410355530318
ko04620	Toll-like receptor signaling pathway	4/716	100/7206	0.0428418767915
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/716	14/7206	0.0430834612861
ko04210	Apoptosis	10/716	180/7206	0.043612318558
ko04350	TGF-beta signaling pathway	4/716	103/7206	0.0440344881743
ko05133	Pertussis	3/716	87/7206	0.0448384788705
ko05166	HTLV-I infection	19/716	292/7206	0.0454997938554
ko00010	Glycolysis / Gluconeogenesis	13/716	74/7206	0.0468296842766
ko04550	Signaling pathways regulating pluripotency of stem cells	9/716	165/7206	0.0485608240683