ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	196/1178	423/7206	8.11860666795e-51
ko04724	Glutamatergic synapse	91/1178	152/7206	1.11298123238e-34
ko05033	Nicotine addiction	50/1178	56/7206	2.30361644835e-33
ko04727	GABAergic synapse	70/1178	110/7206	3.1450046628e-29
ko05032	Morphine addiction	70/1178	110/7206	3.1450046628e-29
ko04713	Circadian entrainment	76/1178	136/7206	2.29502974492e-26
ko04728	Dopaminergic synapse	86/1178	185/7206	2.2203013317e-22
ko04725	Cholinergic synapse	78/1178	160/7206	5.3284335585e-22
ko04723	Retrograde endocannabinoid signaling	80/1178	175/7206	2.56301228479e-20
ko04721	Synaptic vesicle cycle	49/1178	80/7206	9.61649583358e-20
ko04024	cAMP signaling pathway	103/1178	279/7206	1.99357187084e-17
ko04911	Insulin secretion	56/1178	117/7206	1.16026401603e-15
ko04744	Phototransduction	27/1178	36/7206	9.36732737111e-15
ko04020	Calcium signaling pathway	94/1178	265/7206	1.34529289497e-14
ko04726	Serotonergic synapse	60/1178	137/7206	1.82716247241e-14
ko04742	Taste transduction	36/1178	61/7206	4.01787112553e-14
ko04921	Oxytocin signaling pathway	77/1178	209/7206	3.14156943572e-13
ko04261	Adrenergic signaling in cardiomyocytes	74/1178	205/7206	3.61971450726e-12
ko05031	Amphetamine addiction	42/1178	91/7206	2.05036028334e-11
ko04720	Long-term potentiation	44/1178	99/7206	3.28300632604e-11
ko03040	Spliceosome	1/1178	145/7206	1.94449142043e-10
ko04970	Salivary secretion	40/1178	95/7206	1.86805714886e-09
ko04360	Axon guidance	72/1178	233/7206	2.16753621032e-08
ko04925	Aldosterone synthesis and secretion	40/1178	105/7206	6.2222985086e-08
ko04740	Olfactory transduction	33/1178	80/7206	8.93707310274e-08
ko04971	Gastric acid secretion	37/1178	98/7206	2.52465777794e-07
ko05030	Cocaine addiction	30/1178	73/7206	3.79339019784e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	30/1178	74/7206	5.39693267367e-07
ko05322	Systemic lupus erythematosus	5/1178	151/7206	5.80682454002e-07
ko05203	Viral carcinogenesis	18/1178	277/7206	8.05299877417e-07
ko03013	RNA transport	7/1178	166/7206	1.91381761581e-06
ko04972	Pancreatic secretion	38/1178	111/7206	3.27925024888e-06
ko05168	Herpes simplex infection	9/1178	182/7206	3.43615502758e-06
ko04060	Cytokine-cytokine receptor interaction	10/1178	191/7206	3.67213480409e-06
ko04010	MAPK signaling pathway	84/1178	321/7206	4.4264242737e-06
ko04141	Protein processing in endoplasmic reticulum	10/1178	184/7206	1.04477043353e-05
ko04070	Phosphatidylinositol signaling system	37/1178	112/7206	1.30336987916e-05
ko04610	Complement and coagulation cascades	1/1178	79/7206	2.03253575611e-05
ko04022	cGMP-PKG signaling pathway	60/1178	216/7206	2.09787578972e-05
ko04621	NOD-like receptor signaling pathway	8/1178	157/7206	2.54492388464e-05
ko04072	Phospholipase D signaling pathway	55/1178	197/7206	3.32485901679e-05
ko04745	Phototransduction - fly	17/1178	38/7206	3.50266111832e-05
ko04730	Long-term depression	27/1178	78/7206	7.33795698638e-05
ko05164	Influenza A	10/1178	167/7206	7.42160287548e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1178	79/7206	8.84097682042e-05
ko04514	Cell adhesion molecules (CAMs)	39/1178	130/7206	9.7680161954e-05
ko04540	Gap junction	38/1178	128/7206	0.000145899275618
ko03008	Ribosome biogenesis in eukaryotes	2/1178	79/7206	0.000171733224882
ko05414	Dilated cardiomyopathy	34/1178	112/7206	0.000240132039289
ko04612	Antigen processing and presentation	2/1178	77/7206	0.000260061828782
ko04961	Endocrine and other factor-regulated calcium reabsorption	21/1178	59/7206	0.000274468298591
ko04966	Collecting duct acid secretion	12/1178	26/7206	0.00035283571272
ko04110	Cell cycle	9/1178	145/7206	0.000374663436235
ko05140	Leishmaniasis	2/1178	75/7206	0.000397033894261
ko04064	NF-kappa B signaling pathway	4/1178	96/7206	0.000406829799578
ko04260	Cardiac muscle contraction	30/1178	98/7206	0.000456134445593
ko04923	Regulation of lipolysis in adipocytes	25/1178	77/7206	0.000478634212327
ko04750	Inflammatory mediator regulation of TRP channels	35/1178	122/7206	0.000491115053804
ko04924	Renin secretion	27/1178	86/7206	0.000565746159226
ko05205	Proteoglycans in cancer	25/1178	271/7206	0.00076764931605
ko05110	Vibrio cholerae infection	21/1178	63/7206	0.000853799779051
ko04014	Ras signaling pathway	67/1178	279/7206	0.000895492672839
ko04120	Ubiquitin mediated proteolysis	9/1178	138/7206	0.0009927960457
ko04976	Bile secretion	25/1178	80/7206	0.00111381409845
ko04915	Estrogen signaling pathway	36/1178	131/7206	0.00114236470904
ko04146	Peroxisome	4/1178	89/7206	0.00123816716263
ko05161	Hepatitis B	14/1178	173/7206	0.00173375056056
ko00590	Arachidonic acid metabolism	1/1178	52/7206	0.00200039042546
ko05162	Measles	8/1178	120/7206	0.00254125451382
ko00240	Pyrimidine metabolism	7/1178	110/7206	0.00257675786719
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1178	14/7206	0.00363457363372
ko05169	Epstein-Barr virus infection	19/1178	206/7206	0.00395836144881
ko04964	Proximal tubule bicarbonate reclamation	11/1178	29/7206	0.00422935469605
ko03420	Nucleotide excision repair	1/1178	46/7206	0.0044159938286
ko04626	Plant-pathogen interaction	8/1178	18/7206	0.00467054682065
ko04657	IL-17 signaling pathway	5/1178	87/7206	0.00503742419167
ko00480	Glutathione metabolism	2/1178	55/7206	0.00569280472073
ko05321	Inflammatory bowel disease (IBD)	2/1178	56/7206	0.00571641539716
ko03022	Basal transcription factors	1/1178	44/7206	0.00669107570794
ko04115	p53 signaling pathway	4/1178	74/7206	0.00683054023122
ko05144	Malaria	1/1178	45/7206	0.00699631770677
ko00071	Fatty acid degradation	1/1178	45/7206	0.00699631770677
ko04912	GnRH signaling pathway	31/1178	122/7206	0.00917994905794
ko04622	RIG-I-like receptor signaling pathway	3/1178	62/7206	0.00922737237583
ko04640	Hematopoietic cell lineage	3/1178	64/7206	0.00961624900729
ko04658	Th1 and Th2 cell differentiation	7/1178	96/7206	0.0121318716767
ko05133	Pertussis	6/1178	87/7206	0.0128031351573
ko03320	PPAR signaling pathway	4/1178	69/7206	0.0134748861882
ko00330	Arginine and proline metabolism	3/1178	61/7206	0.013488824107
ko04930	Type II diabetes mellitus	16/1178	54/7206	0.0145716728572
ko03410	Base excision repair	1/1178	38/7206	0.0148682234414
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1178	40/7206	0.0157125320755
ko04510	Focal adhesion	26/1178	240/7206	0.0165204449472
ko04722	Neurotrophin signaling pathway	38/1178	160/7206	0.0167615607741
ko03018	RNA degradation	6/1178	84/7206	0.0174429864697
ko04371	Apelin signaling pathway	41/1178	177/7206	0.0174759743936
ko00260	Glycine, serine and threonine metabolism	2/1178	48/7206	0.0175997959096
ko05145	Toxoplasmosis	11/1178	126/7206	0.0201259887296
ko00982	Drug metabolism - cytochrome P450	1/1178	37/7206	0.0228864371199
ko04217	Necroptosis	18/1178	178/7206	0.0233948682714
ko05131	Shigellosis	6/1178	82/7206	0.0236300491021
ko05231	Choline metabolism in cancer	32/1178	134/7206	0.0242360451349
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/1178	15/7206	0.0249453637263
ko00310	Lysine degradation	5/1178	73/7206	0.0251150527153
ko00280	Valine, leucine and isoleucine degradation	3/1178	54/7206	0.0264440638994
ko04918	Thyroid hormone synthesis	22/1178	86/7206	0.0267750735648
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1178	100/7206	0.0280574518576
ko05166	HTLV-I infection	34/1178	292/7206	0.0287686478919
ko04916	Melanogenesis	33/1178	142/7206	0.0292424045146
ko04210	Apoptosis	19/1178	180/7206	0.0319383347392
ko04932	Non-alcoholic fatty liver disease (NAFLD)	19/1178	182/7206	0.0323092050123
ko00500	Starch and sucrose metabolism	1/1178	35/7206	0.0350203329093
ko04214	Apoptosis - fly	5/1178	72/7206	0.0353598817146
ko00983	Drug metabolism - other enzymes	2/1178	42/7206	0.0367269365602
ko04114	Oocyte meiosis	32/1178	139/7206	0.0368023117676
ko05016	Huntington's disease	24/1178	215/7206	0.038944103272
ko04062	Chemokine signaling pathway	44/1178	201/7206	0.0415035103028
ko04630	Jak-STAT signaling pathway	13/1178	132/7206	0.0428771752686
ko04711	Circadian rhythm - fly	5/1178	13/7206	0.0473973636709
ko05340	Primary immunodeficiency	1/1178	30/7206	0.0493069898668