ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	28/283	152/7206	4.20086060349e-12
ko04728	Dopaminergic synapse	29/283	185/7206	1.06695823578e-10
ko04727	GABAergic synapse	20/283	110/7206	7.05218738641e-09
ko05033	Nicotine addiction	14/283	56/7206	1.9818183215e-08
ko05032	Morphine addiction	16/283	110/7206	5.21849271806e-06
ko04514	Cell adhesion molecules (CAMs)	17/283	130/7206	1.14886053997e-05
ko04721	Synaptic vesicle cycle	13/283	80/7206	1.18918666568e-05
ko04713	Circadian entrainment	17/283	136/7206	2.10233207833e-05
ko05030	Cocaine addiction	12/283	73/7206	2.29297724236e-05
ko04723	Retrograde endocannabinoid signaling	19/283	175/7206	5.14808288962e-05
ko04726	Serotonergic synapse	16/283	137/7206	8.49233693603e-05
ko04261	Adrenergic signaling in cardiomyocytes	20/283	205/7206	0.000147767003597
ko05031	Amphetamine addiction	12/283	91/7206	0.000209299169254
ko04024	cAMP signaling pathway	24/283	279/7206	0.000376754489899
ko04725	Cholinergic synapse	16/283	160/7206	0.000516076614499
ko04010	MAPK signaling pathway	26/283	321/7206	0.000543193243855
ko05213	Endometrial cancer	9/283	62/7206	0.000636285579405
ko05014	Amyotrophic lateral sclerosis (ALS)	9/283	74/7206	0.00229857409034
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	9/283	79/7206	0.00360891259124
ko04720	Long-term potentiation	10/283	99/7206	0.00529006671114
ko04071	Sphingolipid signaling pathway	14/283	162/7206	0.00589166329666
ko04080	Neuroactive ligand-receptor interaction	28/283	423/7206	0.00622262607978
ko04730	Long-term depression	8/283	78/7206	0.0110909157896
ko05214	Glioma	8/283	79/7206	0.0119339584035
ko04740	Olfactory transduction	8/283	80/7206	0.0128232715617
ko04360	Axon guidance	17/283	233/7206	0.014472249714
ko04930	Type II diabetes mellitus	6/283	54/7206	0.0184731458907
ko04621	NOD-like receptor signaling pathway	1/283	157/7206	0.0217002623066
ko04911	Insulin secretion	10/283	117/7206	0.0252341826706
ko00512	Mucin type O-glycan biosynthesis	4/283	29/7206	0.0255123516141
ko05203	Viral carcinogenesis	4/283	277/7206	0.0260644306923
ko04921	Oxytocin signaling pathway	15/283	209/7206	0.0271385784696
ko05120	Epithelial cell signaling in Helicobacter pylori infection	8/283	92/7206	0.0275939274875
ko04915	Estrogen signaling pathway	10/283	131/7206	0.0379394570031
ko04014	Ras signaling pathway	18/283	279/7206	0.0387100707643
ko04012	ErbB signaling pathway	9/283	109/7206	0.0393491705067
ko04070	Phosphatidylinositol signaling system	9/283	112/7206	0.0424164720801
ko05223	Non-small cell lung cancer	6/283	66/7206	0.0441617462704
ko03040	Spliceosome	1/283	145/7206	0.0469952840017
ko05218	Melanoma	7/283	85/7206	0.0488617925371