ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	195/1327	423/7206	1.17628208334e-41
ko04724	Glutamatergic synapse	88/1327	152/7206	5.7828494004e-28
ko05032	Morphine addiction	68/1327	110/7206	3.80200316508e-24
ko05033	Nicotine addiction	45/1327	56/7206	8.27957365635e-24
ko04713	Circadian entrainment	74/1327	136/7206	1.94597572864e-21
ko04727	GABAergic synapse	64/1327	110/7206	8.9102465317e-21
ko04725	Cholinergic synapse	78/1327	160/7206	1.02451103151e-18
ko04020	Calcium signaling pathway	109/1327	265/7206	2.30056294765e-18
ko04728	Dopaminergic synapse	84/1327	185/7206	1.22668854624e-17
ko04024	cAMP signaling pathway	111/1327	279/7206	2.14093339353e-17
ko04721	Synaptic vesicle cycle	46/1327	80/7206	5.22387627846e-15
ko04723	Retrograde endocannabinoid signaling	76/1327	175/7206	9.37434215582e-15
ko04921	Oxytocin signaling pathway	86/1327	209/7206	1.07444988582e-14
ko04911	Insulin secretion	56/1327	117/7206	2.38852648765e-13
ko04726	Serotonergic synapse	62/1327	137/7206	3.01049811555e-13
ko04261	Adrenergic signaling in cardiomyocytes	78/1327	205/7206	2.33719315134e-11
ko04742	Taste transduction	34/1327	61/7206	6.41627629393e-11
ko04022	cGMP-PKG signaling pathway	79/1327	216/7206	1.61646725966e-10
ko03010	Ribosome	1/1327	129/7206	2.11473888356e-10
ko05031	Amphetamine addiction	43/1327	91/7206	2.50495927191e-10
ko04970	Salivary secretion	44/1327	95/7206	3.50101349487e-10
ko03040	Spliceosome	3/1327	145/7206	1.4865685619e-09
ko05322	Systemic lupus erythematosus	4/1327	151/7206	3.67614181701e-09
ko04744	Phototransduction	22/1327	36/7206	1.56003877285e-08
ko04925	Aldosterone synthesis and secretion	43/1327	105/7206	6.44754164415e-08
ko04720	Long-term potentiation	41/1327	99/7206	1.11094966494e-07
ko03013	RNA transport	8/1327	166/7206	2.64961254422e-07
ko04971	Gastric acid secretion	39/1327	98/7206	5.85087435023e-07
ko05203	Viral carcinogenesis	22/1327	277/7206	7.51180642482e-07
ko04072	Phospholipase D signaling pathway	65/1327	197/7206	8.45757826687e-07
ko04070	Phosphatidylinositol signaling system	42/1327	112/7206	1.64510372636e-06
ko04110	Cell cycle	7/1327	145/7206	2.10442456918e-06
ko04010	MAPK signaling pathway	92/1327	321/7206	4.27107590859e-06
ko05030	Cocaine addiction	30/1327	73/7206	5.38704009382e-06
ko04014	Ras signaling pathway	81/1327	279/7206	1.2405483388e-05
ko04924	Renin secretion	33/1327	86/7206	1.48456218752e-05
ko04730	Long-term depression	30/1327	78/7206	2.62466947577e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1327	79/7206	2.79896064076e-05
ko04360	Axon guidance	68/1327	233/7206	4.68471052918e-05
ko04966	Collecting duct acid secretion	14/1327	26/7206	5.06403832622e-05
ko04514	Cell adhesion molecules (CAMs)	43/1327	130/7206	5.08347199244e-05
ko05168	Herpes simplex infection	14/1327	182/7206	5.92566296778e-05
ko04371	Apelin signaling pathway	54/1327	177/7206	7.46411561144e-05
ko04922	Glucagon signaling pathway	42/1327	128/7206	7.51405747198e-05
ko04923	Regulation of lipolysis in adipocytes	29/1327	77/7206	7.61094904308e-05
ko04915	Estrogen signaling pathway	42/1327	131/7206	0.000144870069421
ko04745	Phototransduction - fly	17/1327	38/7206	0.000165819537149
ko04270	Vascular smooth muscle contraction	47/1327	154/7206	0.000212662112977
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1327	74/7206	0.000215296118441
ko04972	Pancreatic secretion	36/1327	111/7206	0.000308602735921
ko00520	Amino sugar and nucleotide sugar metabolism	1/1327	55/7206	0.00032463789363
ko04750	Inflammatory mediator regulation of TRP channels	39/1327	122/7206	0.00033728101485
ko04710	Circadian rhythm	18/1327	43/7206	0.000452311380409
ko04540	Gap junction	40/1327	128/7206	0.000471460070959
ko04141	Protein processing in endoplasmic reticulum	17/1327	184/7206	0.000684148508252
ko04930	Type II diabetes mellitus	20/1327	54/7206	0.00115624566384
ko05110	Vibrio cholerae infection	22/1327	63/7206	0.00162522277
ko03420	Nucleotide excision repair	1/1327	46/7206	0.0017449419612
ko04120	Ubiquitin mediated proteolysis	12/1327	138/7206	0.00179380544127
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1327	79/7206	0.00187427863744
ko05414	Dilated cardiomyopathy	34/1327	112/7206	0.00194520697267
ko04740	Olfactory transduction	26/1327	80/7206	0.00211681678225
ko04976	Bile secretion	26/1327	80/7206	0.00211681678225
ko05164	Influenza A	16/1327	167/7206	0.00227117745919
ko05169	Epstein-Barr virus infection	22/1327	206/7206	0.0025553161228
ko03022	Basal transcription factors	1/1327	44/7206	0.00267803680688
ko04622	RIG-I-like receptor signaling pathway	3/1327	62/7206	0.00279146781517
ko04015	Rap1 signaling pathway	70/1327	278/7206	0.00436772676237
ko05231	Choline metabolism in cancer	38/1327	134/7206	0.00461128543856
ko05230	Central carbon metabolism in cancer	25/1327	81/7206	0.00584174974965
ko03410	Base excision repair	1/1327	38/7206	0.00604571201517
ko04960	Aldosterone-regulated sodium reabsorption	15/1327	41/7206	0.006941891913
ko04973	Carbohydrate digestion and absorption	15/1327	42/7206	0.00789041784855
ko04626	Plant-pathogen interaction	8/1327	18/7206	0.00982657351879
ko05130	Pathogenic Escherichia coli infection	6/1327	77/7206	0.0118005100151
ko04612	Antigen processing and presentation	6/1327	77/7206	0.0118005100151
ko04621	NOD-like receptor signaling pathway	17/1327	157/7206	0.012114472639
ko00280	Valine, leucine and isoleucine degradation	3/1327	54/7206	0.0123197949786
ko04260	Cardiac muscle contraction	28/1327	98/7206	0.0123247061073
ko04964	Proximal tubule bicarbonate reclamation	11/1327	29/7206	0.0133340124383
ko00860	Porphyrin and chlorophyll metabolism	1/1327	34/7206	0.0136994157286
ko05205	Proteoglycans in cancer	35/1327	271/7206	0.0163900746657
ko05161	Hepatitis B	20/1327	173/7206	0.0169747504129
ko04912	GnRH signaling pathway	33/1327	122/7206	0.0178884059558
ko05214	Glioma	23/1327	79/7206	0.0188063994885
ko04711	Circadian rhythm - fly	6/1327	13/7206	0.020333042136
ko05131	Shigellosis	7/1327	82/7206	0.0207597629012
ko00965	Betalain biosynthesis	3/1327	4/7206	0.0214964405926
ko04064	NF-kappa B signaling pathway	9/1327	96/7206	0.023177898581
ko04657	IL-17 signaling pathway	8/1327	87/7206	0.025153287527
ko05133	Pertussis	8/1327	87/7206	0.025153287527
ko00562	Inositol phosphate metabolism	25/1327	89/7206	0.026474019985
ko04919	Thyroid hormone signaling pathway	37/1327	143/7206	0.0285246258046
ko04113	Meiosis - yeast	6/1327	70/7206	0.0298737108077
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1327	14/7206	0.0301508558102
ko05320	Autoimmune thyroid disease	1/1327	29/7206	0.0310827032541
ko03018	RNA degradation	8/1327	84/7206	0.0332511264398
ko04213	Longevity regulating pathway - multiple species	24/1327	86/7206	0.0343564142611
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1327	100/7206	0.036426866623
ko00230	Purine metabolism	47/1327	194/7206	0.0386708092096
ko04217	Necroptosis	22/1327	178/7206	0.0391168221989
ko04146	Peroxisome	9/1327	89/7206	0.0393330889353
ko05016	Huntington's disease	28/1327	215/7206	0.0396295961634
ko04142	Lysosome	18/1327	151/7206	0.0429959110412
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1327	59/7206	0.0435446639557
ko00240	Pyrimidine metabolism	12/1327	110/7206	0.0462760110876
ko00310	Lysine degradation	7/1327	73/7206	0.0489151176776
ko04115	p53 signaling pathway	7/1327	74/7206	0.0490225046167