ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	180/1102	423/7206	2.09619313843e-44
ko04724	Glutamatergic synapse	85/1102	152/7206	1.29774730637e-31
ko05033	Nicotine addiction	46/1102	56/7206	1.02239685268e-28
ko05032	Morphine addiction	64/1102	110/7206	2.41763946157e-25
ko04728	Dopaminergic synapse	85/1102	185/7206	9.99227299036e-24
ko04713	Circadian entrainment	69/1102	136/7206	1.58535294557e-22
ko04727	GABAergic synapse	60/1102	110/7206	7.83135461163e-22
ko04725	Cholinergic synapse	70/1102	160/7206	2.94634649398e-18
ko04723	Retrograde endocannabinoid signaling	73/1102	175/7206	1.40151290051e-17
ko04024	cAMP signaling pathway	98/1102	279/7206	5.44357769241e-17
ko04726	Serotonergic synapse	59/1102	137/7206	3.46827534676e-15
ko04020	Calcium signaling pathway	91/1102	265/7206	4.26181664957e-15
ko04721	Synaptic vesicle cycle	42/1102	80/7206	7.3702019547e-15
ko04911	Insulin secretion	52/1102	117/7206	3.30226009794e-14
ko05031	Amphetamine addiction	43/1102	91/7206	4.23429384046e-13
ko04744	Phototransduction	24/1102	36/7206	4.18910351615e-12
ko04742	Taste transduction	32/1102	61/7206	1.28382688728e-11
ko04921	Oxytocin signaling pathway	70/1102	209/7206	2.89836295895e-11
ko04720	Long-term potentiation	42/1102	99/7206	6.36664799376e-11
ko04925	Aldosterone synthesis and secretion	41/1102	105/7206	2.23693012481e-09
ko04261	Adrenergic signaling in cardiomyocytes	64/1102	205/7206	5.22875546871e-09
ko03040	Spliceosome	2/1102	145/7206	1.64141979988e-08
ko03010	Ribosome	1/1102	129/7206	1.74557205081e-08
ko05030	Cocaine addiction	31/1102	73/7206	2.01580497776e-08
ko05322	Systemic lupus erythematosus	4/1102	151/7206	4.92070199628e-07
ko04970	Salivary secretion	34/1102	95/7206	7.38846122821e-07
ko04971	Gastric acid secretion	34/1102	98/7206	1.47705305951e-06
ko04070	Phosphatidylinositol signaling system	37/1102	112/7206	2.04696256805e-06
ko03013	RNA transport	7/1102	166/7206	9.00553285812e-06
ko04745	Phototransduction - fly	17/1102	38/7206	1.42535030628e-05
ko04022	cGMP-PKG signaling pathway	57/1102	216/7206	1.92333595578e-05
ko04730	Long-term depression	27/1102	78/7206	1.98927837407e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1102	74/7206	2.29821264431e-05
ko04110	Cell cycle	6/1102	145/7206	3.30043600332e-05
ko04141	Protein processing in endoplasmic reticulum	10/1102	184/7206	4.23446027756e-05
ko04072	Phospholipase D signaling pathway	52/1102	197/7206	4.79891341301e-05
ko05203	Viral carcinogenesis	20/1102	277/7206	5.48427503457e-05
ko04060	Cytokine-cytokine receptor interaction	11/1102	191/7206	5.9091680946e-05
ko05168	Herpes simplex infection	10/1102	182/7206	5.94941528039e-05
ko04010	MAPK signaling pathway	76/1102	321/7206	6.44200522074e-05
ko04514	Cell adhesion molecules (CAMs)	37/1102	130/7206	0.000106898449706
ko04740	Olfactory transduction	26/1102	80/7206	0.00011073140091
ko04750	Inflammatory mediator regulation of TRP channels	35/1102	122/7206	0.00017891461982
ko04972	Pancreatic secretion	32/1102	111/7206	0.000256996112881
ko04621	NOD-like receptor signaling pathway	9/1102	157/7206	0.000290691075697
ko04915	Estrogen signaling pathway	36/1102	131/7206	0.000310863814098
ko04710	Circadian rhythm	16/1102	43/7206	0.000355340687723
ko03008	Ribosome biogenesis in eukaryotes	2/1102	79/7206	0.000410101893692
ko04612	Antigen processing and presentation	2/1102	77/7206	0.000620747603027
ko05162	Measles	6/1102	120/7206	0.000744888444072
ko04120	Ubiquitin mediated proteolysis	8/1102	138/7206	0.00075754563045
ko04360	Axon guidance	55/1102	233/7206	0.000791086040348
ko04064	NF-kappa B signaling pathway	4/1102	96/7206	0.000884620977644
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1102	79/7206	0.00146016714428
ko04014	Ras signaling pathway	62/1102	279/7206	0.00164217840616
ko04922	Glucagon signaling pathway	33/1102	128/7206	0.00178167409638
ko04540	Gap junction	33/1102	128/7206	0.00178167409638
ko05164	Influenza A	12/1102	167/7206	0.00214795038549
ko04924	Renin secretion	24/1102	86/7206	0.00230439107916
ko04626	Plant-pathogen interaction	8/1102	18/7206	0.00304258618065
ko05169	Epstein-Barr virus infection	17/1102	206/7206	0.0030890880922
ko05140	Leishmaniasis	3/1102	75/7206	0.00330440635053
ko04260	Cardiac muscle contraction	26/1102	98/7206	0.00415948358645
ko04630	Jak-STAT signaling pathway	9/1102	132/7206	0.00465308589884
ko04930	Type II diabetes mellitus	16/1102	54/7206	0.0067704036507
ko03420	Nucleotide excision repair	1/1102	46/7206	0.0069544000732
ko05231	Choline metabolism in cancer	32/1102	134/7206	0.00754015357498
ko04711	Circadian rhythm - fly	6/1102	13/7206	0.00823582804905
ko04964	Proximal tubule bicarbonate reclamation	10/1102	29/7206	0.00837769312203
ko04973	Carbohydrate digestion and absorption	13/1102	42/7206	0.00879599102463
ko03022	Basal transcription factors	1/1102	44/7206	0.010419591074
ko05144	Malaria	1/1102	45/7206	0.0107436524562
ko05200	Pathways in cancer	56/1102	492/7206	0.0113399182415
ko04966	Collecting duct acid secretion	9/1102	26/7206	0.0118504882886
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1102	14/7206	0.0125753137409
ko05414	Dilated cardiomyopathy	27/1102	112/7206	0.0162600472345
ko00562	Inositol phosphate metabolism	22/1102	89/7206	0.0173518371503
ko05145	Toxoplasmosis	10/1102	126/7206	0.0174522662045
ko04330	Notch signaling pathway	3/1102	62/7206	0.0196657671773
ko03410	Base excision repair	1/1102	38/7206	0.0230006863881
ko04918	Thyroid hormone synthesis	21/1102	86/7206	0.0232964046549
ko05161	Hepatitis B	16/1102	173/7206	0.0243424425457
ko04657	IL-17 signaling pathway	6/1102	87/7206	0.0244461370782
ko05133	Pertussis	6/1102	87/7206	0.0244461370782
ko04960	Aldosterone-regulated sodium reabsorption	12/1102	41/7206	0.0258417380443
ko05130	Pathogenic Escherichia coli infection	5/1102	77/7206	0.0259888206122
ko05219	Bladder cancer	2/1102	48/7206	0.0263106287451
ko04610	Complement and coagulation cascades	5/1102	79/7206	0.0263146542328
ko04976	Bile secretion	20/1102	80/7206	0.0270008236195
ko05034	Alcoholism	49/1102	238/7206	0.0274288024299
ko04113	Meiosis - yeast	4/1102	70/7206	0.0280485842896
ko04658	Th1 and Th2 cell differentiation	7/1102	96/7206	0.0308477495533
ko03018	RNA degradation	6/1102	84/7206	0.0328901653477
ko04975	Fat digestion and absorption	1/1102	35/7206	0.0341758447739
ko04217	Necroptosis	17/1102	178/7206	0.034191592867
ko05016	Huntington's disease	22/1102	215/7206	0.0343606604173
ko04672	Intestinal immune network for IgA production	1/1102	37/7206	0.0354388197016
ko05166	HTLV-I infection	32/1102	292/7206	0.0375990467957
ko00071	Fatty acid degradation	2/1102	45/7206	0.037834542303
ko05416	Viral myocarditis	3/1102	55/7206	0.038379348629
ko05321	Inflammatory bowel disease (IBD)	3/1102	56/7206	0.0386188709996
ko05214	Glioma	19/1102	79/7206	0.0394697111345
ko04912	GnRH signaling pathway	27/1102	122/7206	0.0416220885998
ko04114	Oocyte meiosis	30/1102	139/7206	0.0428086981068
ko05131	Shigellosis	6/1102	82/7206	0.0440397499893
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1102	182/7206	0.0466278701564
ko04214	Apoptosis - fly	5/1102	72/7206	0.0477642183532
ko05205	Proteoglycans in cancer	30/1102	271/7206	0.0479785039172
ko00310	Lysine degradation	5/1102	73/7206	0.0481693024514
ko04115	p53 signaling pathway	5/1102	74/7206	0.0491332660306