ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 20/168 157/7206 4.46761401289e-10 ko04380 Osteoclast differentiation 18/168 134/7206 1.47478420112e-09 ko04060 Cytokine-cytokine receptor interaction 21/168 191/7206 2.49439910202e-09 ko05164 Influenza A 19/168 167/7206 8.59670294785e-09 ko04064 NF-kappa B signaling pathway 14/168 96/7206 3.70979876107e-08 ko04620 Toll-like receptor signaling pathway 14/168 100/7206 6.31764898948e-08 ko05321 Inflammatory bowel disease (IBD) 10/168 56/7206 5.12255024043e-07 ko05162 Measles 14/168 120/7206 6.38500839317e-07 ko04217 Necroptosis 17/168 178/7206 7.0726951525e-07 ko04660 T cell receptor signaling pathway 14/168 124/7206 9.56848880773e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/168 191/7206 1.9048535657e-06 ko04650 Natural killer cell mediated cytotoxicity 12/168 97/7206 2.22542832349e-06 ko05161 Hepatitis B 16/168 173/7206 2.34670825909e-06 ko04630 Jak-STAT signaling pathway 13/168 132/7206 1.09535642935e-05 ko05160 Hepatitis C 13/168 153/7206 5.32251626459e-05 ko04658 Th1 and Th2 cell differentiation 10/168 96/7206 7.26882920695e-05 ko05168 Herpes simplex infection 14/168 182/7206 8.17134377578e-05 ko04622 RIG-I-like receptor signaling pathway 8/168 62/7206 8.55022894636e-05 ko04668 TNF signaling pathway 11/168 120/7206 0.000102750031198 ko05152 Tuberculosis 14/168 187/7206 0.000109455932424 ko05145 Toxoplasmosis 11/168 126/7206 0.000159414437826 ko04662 B cell receptor signaling pathway 9/168 88/7206 0.000193450480048 ko05323 Rheumatoid arthritis 9/168 89/7206 0.000210971841402 ko05140 Leishmaniasis 8/168 75/7206 0.00032996560682 ko04664 Fc epsilon RI signaling pathway 8/168 77/7206 0.000395614593919 ko05144 Malaria 6/168 45/7206 0.000562866351228 ko05133 Pertussis 8/168 87/7206 0.000902070083085 ko04210 Apoptosis 12/168 180/7206 0.000971983444647 ko05166 HTLV-I infection 16/168 292/7206 0.0012296160078 ko04611 Platelet activation 11/168 163/7206 0.00142994276941 ko04672 Intestinal immune network for IgA production 5/168 37/7206 0.00154600467086 ko05134 Legionellosis 7/168 74/7206 0.00159942764226 ko04666 Fc gamma R-mediated phagocytosis 9/168 122/7206 0.00210253447134 ko04623 Cytosolic DNA-sensing pathway 5/168 41/7206 0.0024659568557 ko04062 Chemokine signaling pathway 12/168 201/7206 0.00249331665026 ko04142 Lysosome 10/168 151/7206 0.00269006680493 ko04659 Th17 cell differentiation 8/168 106/7206 0.00320519885959 ko04080 Neuroactive ligand-receptor interaction 2/168 423/7206 0.00424336279501 ko04145 Phagosome 10/168 162/7206 0.00445968211343 ko05340 Primary immunodeficiency 4/168 30/7206 0.00486665847159 ko05132 Salmonella infection 7/168 98/7206 0.00772373105874 ko05150 Staphylococcus aureus infection 4/168 36/7206 0.00938902234405 ko04610 Complement and coagulation cascades 6/168 79/7206 0.0100331043479 ko05142 Chagas disease (American trypanosomiasis) 8/168 130/7206 0.0107992005811 ko05131 Shigellosis 6/168 82/7206 0.0119405261184 ko04933 AGE-RAGE signaling pathway in diabetic complications 8/168 135/7206 0.0133612738997 ko04917 Prolactin signaling pathway 6/168 87/7206 0.0156656420049 ko05330 Allograft rejection 3/168 24/7206 0.0175843509344 ko05418 Fluid shear stress and atherosclerosis 9/168 173/7206 0.0195490755561 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/168 92/7206 0.0201288099772 ko04670 Leukocyte transendothelial migration 8/168 151/7206 0.0245500319522 ko05169 Epstein-Barr virus infection 10/168 206/7206 0.0291666250746 ko04612 Antigen processing and presentation 5/168 77/7206 0.0333684315255 ko04070 Phosphatidylinositol signaling system 6/168 112/7206 0.0464074964911