ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	201/1087	423/7206	1.11237087912e-60
ko04724	Glutamatergic synapse	87/1087	152/7206	7.29345374208e-34
ko05033	Nicotine addiction	49/1087	56/7206	1.74354816555e-33
ko05032	Morphine addiction	68/1087	110/7206	1.71969827379e-29
ko04713	Circadian entrainment	74/1087	136/7206	5.45418347887e-27
ko04727	GABAergic synapse	64/1087	110/7206	1.09463232841e-25
ko04728	Dopaminergic synapse	83/1087	185/7206	9.5603275805e-23
ko04721	Synaptic vesicle cycle	50/1087	80/7206	2.83853817676e-22
ko04725	Cholinergic synapse	75/1087	160/7206	4.52344069987e-22
ko04723	Retrograde endocannabinoid signaling	77/1087	175/7206	1.55966978614e-20
ko04024	cAMP signaling pathway	104/1087	279/7206	1.71998410699e-20
ko04020	Calcium signaling pathway	97/1087	265/7206	1.16253162315e-18
ko04911	Insulin secretion	57/1087	117/7206	5.0819870769e-18
ko04742	Taste transduction	38/1087	61/7206	3.80251506857e-17
ko04726	Serotonergic synapse	59/1087	137/7206	1.82343742869e-15
ko04921	Oxytocin signaling pathway	77/1087	209/7206	4.12175609509e-15
ko04261	Adrenergic signaling in cardiomyocytes	72/1087	205/7206	5.03405931222e-13
ko05031	Amphetamine addiction	42/1087	91/7206	1.34097775089e-12
ko04720	Long-term potentiation	44/1087	99/7206	1.98461533288e-12
ko04970	Salivary secretion	40/1087	95/7206	1.57147857187e-10
ko04925	Aldosterone synthesis and secretion	42/1087	105/7206	3.81493292788e-10
ko03040	Spliceosome	1/1087	145/7206	2.24419773275e-09
ko04360	Axon guidance	70/1087	233/7206	3.6851362208e-09
ko04971	Gastric acid secretion	38/1087	98/7206	7.39520137512e-09
ko05030	Cocaine addiction	31/1087	73/7206	1.44614231338e-08
ko04744	Phototransduction	20/1087	36/7206	2.05328696151e-08
ko05203	Viral carcinogenesis	13/1087	277/7206	4.31267295616e-08
ko05168	Herpes simplex infection	5/1087	182/7206	4.67102328605e-08
ko04740	Olfactory transduction	32/1087	80/7206	4.78674845405e-08
ko04060	Cytokine-cytokine receptor interaction	7/1087	191/7206	5.24139787671e-07
ko04022	cGMP-PKG signaling pathway	61/1087	216/7206	5.40496309959e-07
ko04010	MAPK signaling pathway	82/1087	321/7206	5.78794176356e-07
ko05322	Systemic lupus erythematosus	4/1087	151/7206	7.60269139329e-07
ko04972	Pancreatic secretion	37/1087	111/7206	1.28942426975e-06
ko04540	Gap junction	40/1087	128/7206	4.05444581541e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1087	74/7206	4.41034341175e-06
ko05164	Influenza A	7/1087	167/7206	9.0205513426e-06
ko04745	Phototransduction - fly	17/1087	38/7206	1.18213114963e-05
ko03013	RNA transport	7/1087	166/7206	1.3349819128e-05
ko04730	Long-term depression	27/1087	78/7206	1.63679431145e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1087	79/7206	2.01283033126e-05
ko05110	Vibrio cholerae infection	23/1087	63/7206	2.21338697396e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	22/1087	59/7206	2.26684114608e-05
ko04966	Collecting duct acid secretion	13/1087	26/7206	2.97117285166e-05
ko04514	Cell adhesion molecules (CAMs)	38/1087	130/7206	3.19083356459e-05
ko04260	Cardiac muscle contraction	31/1087	98/7206	4.25166328402e-05
ko04924	Renin secretion	28/1087	86/7206	4.65415097332e-05
ko04141	Protein processing in endoplasmic reticulum	10/1087	184/7206	5.99581067141e-05
ko05414	Dilated cardiomyopathy	33/1087	112/7206	8.55729249534e-05
ko04120	Ubiquitin mediated proteolysis	6/1087	138/7206	9.53553927617e-05
ko04750	Inflammatory mediator regulation of TRP channels	35/1087	122/7206	9.95026317432e-05
ko04621	NOD-like receptor signaling pathway	8/1087	157/7206	0.000108562078463
ko04072	Phospholipase D signaling pathway	50/1087	197/7206	0.000158698462337
ko04070	Phosphatidylinositol signaling system	32/1087	112/7206	0.000249466907598
ko05169	Epstein-Barr virus infection	14/1087	206/7206	0.000340269238746
ko03008	Ribosome biogenesis in eukaryotes	2/1087	79/7206	0.000412242067391
ko04014	Ras signaling pathway	64/1087	279/7206	0.000429421114499
ko04915	Estrogen signaling pathway	35/1087	131/7206	0.000481678229205
ko04110	Cell cycle	8/1087	145/7206	0.000575390455613
ko04612	Antigen processing and presentation	2/1087	77/7206	0.000610088579506
ko04976	Bile secretion	24/1087	80/7206	0.000723646204306
ko05162	Measles	6/1087	120/7206	0.000739029920183
ko05140	Leishmaniasis	2/1087	75/7206	0.000915686559163
ko04371	Apelin signaling pathway	43/1087	177/7206	0.00128138419722
ko05205	Proteoglycans in cancer	23/1087	271/7206	0.00130447702459
ko04064	NF-kappa B signaling pathway	4/1087	96/7206	0.00131831582185
ko00480	Glutathione metabolism	1/1087	55/7206	0.0020940239325
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1087	14/7206	0.00225754119929
ko04146	Peroxisome	4/1087	89/7206	0.00258028354068
ko04626	Plant-pathogen interaction	8/1087	18/7206	0.00278332975807
ko00240	Pyrimidine metabolism	6/1087	110/7206	0.00280609024795
ko04912	GnRH signaling pathway	31/1087	122/7206	0.00298119291571
ko00590	Arachidonic acid metabolism	1/1087	52/7206	0.00314151382214
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/1087	182/7206	0.00318814549506
ko04640	Hematopoietic cell lineage	2/1087	64/7206	0.00422462549965
ko00310	Lysine degradation	3/1087	73/7206	0.00478062116723
ko04923	Regulation of lipolysis in adipocytes	21/1087	77/7206	0.00567442257232
ko04330	Notch signaling pathway	2/1087	62/7206	0.00635429407292
ko05161	Hepatitis B	14/1087	173/7206	0.00702870643008
ko00260	Glycine, serine and threonine metabolism	1/1087	48/7206	0.0071672611152
ko04964	Proximal tubule bicarbonate reclamation	10/1087	29/7206	0.00760142677477
ko04015	Rap1 signaling pathway	58/1087	278/7206	0.00793675382295
ko04918	Thyroid hormone synthesis	22/1087	86/7206	0.00954371738257
ko04657	IL-17 signaling pathway	5/1087	87/7206	0.0101304106116
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1087	100/7206	0.0104049861567
ko03022	Basal transcription factors	1/1087	44/7206	0.0104661492683
ko04217	Necroptosis	15/1087	178/7206	0.0105570353421
ko05144	Malaria	1/1087	45/7206	0.0105992934679
ko00071	Fatty acid degradation	1/1087	45/7206	0.0105992934679
ko03420	Nucleotide excision repair	1/1087	46/7206	0.0110453183715
ko05166	HTLV-I infection	29/1087	292/7206	0.0119797177435
ko05321	Inflammatory bowel disease (IBD)	2/1087	56/7206	0.0131131792086
ko04630	Jak-STAT signaling pathway	10/1087	132/7206	0.0134987996898
ko04658	Th1 and Th2 cell differentiation	6/1087	96/7206	0.013689260483
ko03018	RNA degradation	5/1087	84/7206	0.0139566883607
ko01524	Platinum drug resistance	4/1087	76/7206	0.0144120090566
ko00983	Drug metabolism - other enzymes	1/1087	42/7206	0.0156867909645
ko05418	Fluid shear stress and atherosclerosis	15/1087	173/7206	0.0173896082913
ko05131	Shigellosis	5/1087	82/7206	0.0191541046469
ko04622	RIG-I-like receptor signaling pathway	3/1087	62/7206	0.0195583944266
ko04214	Apoptosis - fly	4/1087	72/7206	0.0196728785733
ko04270	Vascular smooth muscle contraction	34/1087	154/7206	0.0220199395509
ko05145	Toxoplasmosis	10/1087	126/7206	0.0230538957334
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1087	40/7206	0.0238144564827
ko03320	PPAR signaling pathway	4/1087	69/7206	0.0272184989851
ko00330	Arginine and proline metabolism	3/1087	61/7206	0.028710292076
ko04916	Melanogenesis	31/1087	142/7206	0.032055967233
ko05133	Pertussis	6/1087	87/7206	0.033444940992
ko05034	Alcoholism	48/1087	238/7206	0.0335644259717
ko04930	Type II diabetes mellitus	14/1087	54/7206	0.0342135674866
ko04210	Apoptosis	17/1087	180/7206	0.0342393092919
ko00982	Drug metabolism - cytochrome P450	1/1087	37/7206	0.0349972077611
ko04140	Autophagy - animal	15/1087	164/7206	0.035133943647
ko04350	TGF-beta signaling pathway	8/1087	103/7206	0.0367201945009
ko00620	Pyruvate metabolism	2/1087	46/7206	0.0380354322041
ko00270	Cysteine and methionine metabolism	2/1087	47/7206	0.0384836887513
ko04114	Oocyte meiosis	30/1087	139/7206	0.0408251582218
ko05016	Huntington's disease	22/1087	215/7206	0.0422444797456
ko05215	Prostate cancer	9/1087	111/7206	0.0436425702646
ko04620	Toll-like receptor signaling pathway	8/1087	100/7206	0.048044160289
ko04115	p53 signaling pathway	5/1087	74/7206	0.0484239072642