ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 25/149 191/7206 7.63181645263e-14 ko05164 Influenza A 19/149 167/7206 1.11568127603e-09 ko05145 Toxoplasmosis 16/149 126/7206 5.05964798605e-09 ko05340 Primary immunodeficiency 9/149 30/7206 5.36015167799e-09 ko04658 Th1 and Th2 cell differentiation 14/149 96/7206 7.88992816927e-09 ko05330 Allograft rejection 8/149 24/7206 1.5388872287e-08 ko04672 Intestinal immune network for IgA production 9/149 37/7206 4.11946865083e-08 ko04064 NF-kappa B signaling pathway 13/149 96/7206 6.8990163263e-08 ko05320 Autoimmune thyroid disease 8/149 29/7206 8.22704496409e-08 ko05321 Inflammatory bowel disease (IBD) 10/149 56/7206 1.66505431781e-07 ko05168 Herpes simplex infection 17/149 182/7206 1.7143507429e-07 ko05152 Tuberculosis 17/149 187/7206 2.54102757326e-07 ko04621 NOD-like receptor signaling pathway 15/149 157/7206 7.13501804471e-07 ko05332 Graft-versus-host disease 6/149 18/7206 1.06879923105e-06 ko04659 Th17 cell differentiation 12/149 106/7206 1.62361239354e-06 ko05140 Leishmaniasis 10/149 75/7206 2.77015788682e-06 ko04380 Osteoclast differentiation 13/149 134/7206 3.44166315468e-06 ko04062 Chemokine signaling pathway 16/149 201/7206 3.44938444531e-06 ko04217 Necroptosis 15/149 178/7206 3.51301509986e-06 ko04650 Natural killer cell mediated cytotoxicity 11/149 97/7206 4.41479701109e-06 ko05162 Measles 12/149 120/7206 6.06675886585e-06 ko04660 T cell receptor signaling pathway 12/149 124/7206 8.53575108426e-06 ko05161 Hepatitis B 14/149 173/7206 1.20779846121e-05 ko05323 Rheumatoid arthritis 10/149 89/7206 1.32697641251e-05 ko05416 Viral myocarditis 8/149 55/7206 1.48065777104e-05 ko05310 Asthma 5/149 17/7206 1.78965815127e-05 ko04612 Antigen processing and presentation 9/149 77/7206 2.64173424379e-05 ko04940 Type I diabetes mellitus 6/149 32/7206 4.10712964333e-05 ko04640 Hematopoietic cell lineage 8/149 64/7206 4.59985009879e-05 ko04514 Cell adhesion molecules (CAMs) 11/149 130/7206 7.19089237289e-05 ko05150 Staphylococcus aureus infection 6/149 36/7206 8.24605816414e-05 ko04630 Jak-STAT signaling pathway 11/149 132/7206 8.26595817723e-05 ko04668 TNF signaling pathway 10/149 120/7206 0.000175302340027 ko04622 RIG-I-like receptor signaling pathway 7/149 62/7206 0.000266371654384 ko05160 Hepatitis C 10/149 153/7206 0.00121230751205 ko04623 Cytosolic DNA-sensing pathway 5/149 41/7206 0.00145342445477 ko05131 Shigellosis 7/149 82/7206 0.00145994205961 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/149 191/7206 0.00194250651553 ko04662 B cell receptor signaling pathway 7/149 88/7206 0.00219960658277 ko05144 Malaria 5/149 45/7206 0.00221776847169 ko05166 HTLV-I infection 14/149 292/7206 0.00277709359133 ko04620 Toll-like receptor signaling pathway 7/149 100/7206 0.00451735207278 ko04145 Phagosome 9/149 162/7206 0.00625833138604 ko05133 Pertussis 6/149 87/7206 0.00902860938825 ko04666 Fc gamma R-mediated phagocytosis 7/149 122/7206 0.0129985771968 ko05132 Salmonella infection 6/149 98/7206 0.0156584821166 ko03050 Proteasome 4/149 54/7206 0.0249728731991 ko04210 Apoptosis 8/149 180/7206 0.0327483434719 ko04917 Prolactin signaling pathway 5/149 87/7206 0.0337316942318 ko04657 IL-17 signaling pathway 5/149 87/7206 0.0337316942318