ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 38/309 79/7206 1.19318611884e-31 ko04975 Fat digestion and absorption 17/309 35/7206 8.1861334365e-15 ko04977 Vitamin digestion and absorption 11/309 22/7206 3.49722452486e-10 ko04974 Protein digestion and absorption 20/309 96/7206 2.67941501175e-09 ko00260 Glycine, serine and threonine metabolism 14/309 48/7206 6.83723457869e-09 ko04973 Carbohydrate digestion and absorption 12/309 42/7206 1.08535746327e-07 ko05150 Staphylococcus aureus infection 11/309 36/7206 1.73519748969e-07 ko00983 Drug metabolism - other enzymes 11/309 42/7206 9.81159882277e-07 ko04950 Maturity onset diabetes of the young 9/309 29/7206 2.0460544642e-06 ko03320 PPAR signaling pathway 13/309 69/7206 5.69028717026e-06 ko04976 Bile secretion 14/309 80/7206 6.15848592898e-06 ko00591 Linoleic acid metabolism 7/309 22/7206 2.43488182171e-05 ko05166 HTLV-I infection 1/309 292/7206 4.90832762687e-05 ko01200 Carbon metabolism 16/309 128/7206 0.000105533488092 ko00270 Cysteine and methionine metabolism 9/309 47/7206 0.000140732638071 ko00630 Glyoxylate and dicarboxylate metabolism 8/309 38/7206 0.000165495963789 ko00980 Metabolism of xenobiotics by cytochrome P450 8/309 40/7206 0.00024150027497 ko04978 Mineral absorption 8/309 40/7206 0.00024150027497 ko01230 Biosynthesis of amino acids 12/309 85/7206 0.000246008967927 ko04972 Pancreatic secretion 14/309 111/7206 0.000258274006708 ko00590 Arachidonic acid metabolism 9/309 52/7206 0.000314634849988 ko05200 Pathways in cancer 7/309 492/7206 0.000460193840418 ko00480 Glutathione metabolism 9/309 55/7206 0.000485656651877 ko00500 Starch and sucrose metabolism 7/309 35/7206 0.000593681413934 ko04010 MAPK signaling pathway 3/309 321/7206 0.000633562318427 ko04614 Renin-angiotensin system 5/309 18/7206 0.00075798068593 ko04360 Axon guidance 1/309 233/7206 0.000758156122338 ko05204 Chemical carcinogenesis 8/309 48/7206 0.000879221322613 ko00010 Glycolysis / Gluconeogenesis 10/309 74/7206 0.00113766673149 ko04964 Proximal tubule bicarbonate reclamation 6/309 29/7206 0.00121872931396 ko04146 Peroxisome 11/309 89/7206 0.00138476724037 ko04920 Adipocytokine signaling pathway 11/309 89/7206 0.00138476724037 ko04144 Endocytosis 4/309 342/7206 0.00144657102201 ko00140 Steroid hormone biosynthesis 7/309 41/7206 0.00159200339628 ko00100 Steroid biosynthesis 5/309 21/7206 0.00161923800618 ko05016 Huntington's disease 1/309 215/7206 0.00163279872306 ko00830 Retinol metabolism 7/309 42/7206 0.00184161226119 ko05169 Epstein-Barr virus infection 1/309 206/7206 0.00239098993677 ko00052 Galactose metabolism 6/309 33/7206 0.0024598559282 ko04922 Glucagon signaling pathway 13/309 128/7206 0.0032115034705 ko05133 Pertussis 10/309 87/7206 0.00387924005287 ko00330 Arginine and proline metabolism 8/309 61/7206 0.00423612176377 ko00040 Pentose and glucuronate interconversions 5/309 26/7206 0.00439047089666 ko00982 Drug metabolism - cytochrome P450 6/309 37/7206 0.00447177622272 ko04152 AMPK signaling pathway 15/309 161/7206 0.00449975864187 ko04141 Protein processing in endoplasmic reticulum 1/309 184/7206 0.00492603927853 ko00380 Tryptophan metabolism 7/309 50/7206 0.00508929166531 ko04217 Necroptosis 1/309 178/7206 0.00734745097296 ko00592 alpha-Linolenic acid metabolism 4/309 19/7206 0.0077097757298 ko04931 Insulin resistance 13/309 137/7206 0.0080750660224 ko00565 Ether lipid metabolism 6/309 42/7206 0.00843661348161 ko00120 Primary bile acid biosynthesis 4/309 20/7206 0.00931771886074 ko03013 RNA transport 1/309 166/7206 0.0104109892415 ko00620 Pyruvate metabolism 6/309 46/7206 0.0130622147404 ko00053 Ascorbate and aldarate metabolism 4/309 22/7206 0.0131527256019 ko05034 Alcoholism 3/309 238/7206 0.0136929323459 ko05012 Parkinson's disease 1/309 155/7206 0.0149638736017 ko04621 NOD-like receptor signaling pathway 1/309 157/7206 0.0150968656471 ko00472 D-Arginine and D-ornithine metabolism 2/309 5/7206 0.0168176567785 ko00232 Caffeine metabolism 2/309 5/7206 0.0168176567785 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/309 5/7206 0.0168176567785 ko00311 Penicillin and cephalosporin biosynthesis 2/309 5/7206 0.0168176567785 ko00561 Glycerolipid metabolism 7/309 63/7206 0.0175900602857 ko00770 Pantothenate and CoA biosynthesis 3/309 14/7206 0.019991080271 ko00340 Histidine metabolism 4/309 25/7206 0.0205706490682 ko00250 Alanine, aspartate and glutamate metabolism 5/309 38/7206 0.0220614890476 ko02010 ABC transporters 5/309 39/7206 0.0244467782458 ko04080 Neuroactive ligand-receptor interaction 9/309 423/7206 0.0248466786666 ko04150 mTOR signaling pathway 2/309 184/7206 0.0251008248346 ko00710 Carbon fixation in photosynthetic organisms 4/309 27/7206 0.0266968026033 ko00240 Pyrimidine metabolism 10/309 110/7206 0.0269792830007 ko05020 Prion diseases 5/309 40/7206 0.0269919330258 ko00520 Amino sugar and nucleotide sugar metabolism 6/309 55/7206 0.0293902265062 ko05203 Viral carcinogenesis 5/309 277/7206 0.033524984009 ko00061 Fatty acid biosynthesis 3/309 17/7206 0.0339763046826 ko00360 Phenylalanine metabolism 3/309 17/7206 0.0339763046826 ko05206 MicroRNAs in cancer 2/309 177/7206 0.0357966720287 ko04921 Oxytocin signaling pathway 3/309 209/7206 0.0359749381129 ko00564 Glycerophospholipid metabolism 9/309 99/7206 0.0383180558851 ko04216 Ferroptosis 5/309 44/7206 0.0388251737044 ko00401 Novobiocin biosynthesis 1/309 1/7206 0.0428809325564 ko00910 Nitrogen metabolism 3/309 19/7206 0.045475420443 ko04550 Signaling pathways regulating pluripotency of stem cells 2/309 165/7206 0.0491933579394 ko04062 Chemokine signaling pathway 3/309 201/7206 0.0495854301959 ko05010 Alzheimer's disease 3/309 202/7206 0.0498590178655