ko pathway ratio_in_study ratio_in_pop p_value ko05410 Hypertrophic cardiomyopathy (HCM) 19/177 100/7206 2.33109145988e-12 ko05414 Dilated cardiomyopathy 17/177 112/7206 1.41150529562e-09 ko04260 Cardiac muscle contraction 16/177 98/7206 1.4616924727e-09 ko00010 Glycolysis / Gluconeogenesis 14/177 74/7206 2.19579843952e-09 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 14/177 79/7206 5.38301545267e-09 ko01200 Carbon metabolism 17/177 128/7206 1.14752561347e-08 ko04261 Adrenergic signaling in cardiomyocytes 21/177 205/7206 2.30986670518e-08 ko04921 Oxytocin signaling pathway 21/177 209/7206 3.25101371519e-08 ko05010 Alzheimer's disease 20/177 202/7206 9.0657742928e-08 ko04922 Glucagon signaling pathway 15/177 128/7206 4.64401208908e-07 ko00190 Oxidative phosphorylation 14/177 127/7206 2.39680551356e-06 ko05012 Parkinson's disease 15/177 155/7206 5.35993431486e-06 ko04020 Calcium signaling pathway 20/177 265/7206 6.82441798893e-06 ko00020 Citrate cycle (TCA cycle) 7/177 35/7206 1.8013320228e-05 ko00500 Starch and sucrose metabolism 7/177 35/7206 1.8013320228e-05 ko04932 Non-alcoholic fatty liver disease (NAFLD) 15/177 182/7206 3.71790021463e-05 ko00710 Carbon fixation in photosynthetic organisms 6/177 27/7206 3.88803768076e-05 ko05016 Huntington's disease 16/177 215/7206 7.07348825758e-05 ko00030 Pentose phosphate pathway 6/177 32/7206 0.00010748041878 ko00680 Methane metabolism 6/177 34/7206 0.000153143006278 ko01230 Biosynthesis of amino acids 9/177 85/7206 0.000219628774471 ko05416 Viral myocarditis 7/177 55/7206 0.00035939022527 ko00051 Fructose and mannose metabolism 6/177 42/7206 0.000507618295051 ko04152 AMPK signaling pathway 12/177 161/7206 0.000573529056785 ko04022 cGMP-PKG signaling pathway 14/177 216/7206 0.000826735265781 ko00620 Pyruvate metabolism 6/177 46/7206 0.000835721735582 ko04723 Retrograde endocannabinoid signaling 11/177 175/7206 0.0037677952058 ko04713 Circadian entrainment 9/177 136/7206 0.00613919628605 ko00052 Galactose metabolism 4/177 33/7206 0.00825571629468 ko04910 Insulin signaling pathway 10/177 172/7206 0.0096358576422 ko04371 Apelin signaling pathway 10/177 177/7206 0.0116485211539 ko04270 Vascular smooth muscle contraction 9/177 154/7206 0.0133513677674 ko05230 Central carbon metabolism in cancer 6/177 81/7206 0.0143153843116 ko04010 MAPK signaling pathway 15/177 321/7206 0.014952914992 ko00521 Streptomycin biosynthesis 2/177 8/7206 0.0152398716622 ko04510 Focal adhesion 12/177 240/7206 0.0172031848381 ko04911 Insulin secretion 7/177 117/7206 0.0247624424325 ko00230 Purine metabolism 10/177 194/7206 0.0284324523879 ko04970 Salivary secretion 6/177 95/7206 0.02901714065 ko04066 HIF-1 signaling pathway 7/177 123/7206 0.0314228208168 ko04971 Gastric acid secretion 6/177 98/7206 0.0331168471371 ko04964 Proximal tubule bicarbonate reclamation 3/177 29/7206 0.0333405370356 ko04930 Type II diabetes mellitus 4/177 54/7206 0.042984634489 ko04740 Olfactory transduction 5/177 80/7206 0.0463784653581