ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	136/781	423/7206	6.19680739432e-35
ko04724	Glutamatergic synapse	74/781	152/7206	1.73570296443e-32
ko05033	Nicotine addiction	40/781	56/7206	7.66294266028e-27
ko05032	Morphine addiction	53/781	110/7206	3.17402837547e-23
ko04727	GABAergic synapse	52/781	110/7206	2.54681680846e-22
ko04723	Retrograde endocannabinoid signaling	63/781	175/7206	3.65187071583e-19
ko04728	Dopaminergic synapse	65/781	185/7206	4.22609319953e-19
ko04721	Synaptic vesicle cycle	40/781	80/7206	1.53382234405e-18
ko04713	Circadian entrainment	53/781	136/7206	4.77834788459e-18
ko04725	Cholinergic synapse	55/781	160/7206	7.7124289285e-16
ko04726	Serotonergic synapse	49/781	137/7206	5.14393976627e-15
ko04744	Phototransduction	22/781	36/7206	3.84886700635e-13
ko04742	Taste transduction	28/781	61/7206	3.47829720142e-12
ko04024	cAMP signaling pathway	70/781	279/7206	5.305035449e-12
ko04911	Insulin secretion	40/781	117/7206	9.22283401722e-12
ko05030	Cocaine addiction	26/781	73/7206	1.58803983379e-08
ko05031	Amphetamine addiction	29/781	91/7206	4.18711261792e-08
ko04720	Long-term potentiation	30/781	99/7206	8.784693063e-08
ko05203	Viral carcinogenesis	7/781	277/7206	1.94309613466e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/781	74/7206	4.28911881873e-07
ko04261	Adrenergic signaling in cardiomyocytes	47/781	205/7206	4.8538144743e-07
ko04060	Cytokine-cytokine receptor interaction	3/781	191/7206	1.29453425726e-06
ko03040	Spliceosome	1/781	145/7206	2.1045222605e-06
ko04921	Oxytocin signaling pathway	46/781	209/7206	2.19648052254e-06
ko04020	Calcium signaling pathway	53/781	265/7206	7.17976356643e-06
ko05164	Influenza A	3/781	167/7206	1.21529272421e-05
ko04730	Long-term depression	22/781	78/7206	1.67058917878e-05
ko04970	Salivary secretion	25/781	95/7206	1.70773281245e-05
ko04120	Ubiquitin mediated proteolysis	2/781	138/7206	3.92567078873e-05
ko04514	Cell adhesion molecules (CAMs)	30/781	130/7206	4.60703989568e-05
ko04010	MAPK signaling pathway	58/781	321/7206	6.84425414786e-05
ko05168	Herpes simplex infection	5/781	182/7206	8.4308103785e-05
ko04971	Gastric acid secretion	24/781	98/7206	0.000100523265478
ko04972	Pancreatic secretion	26/781	111/7206	0.000140764205297
ko05322	Systemic lupus erythematosus	4/781	151/7206	0.000286877279456
ko04022	cGMP-PKG signaling pathway	41/781	216/7206	0.000318078440218
ko03013	RNA transport	5/781	166/7206	0.000330422537841
ko04740	Olfactory transduction	20/781	80/7206	0.000347928784563
ko04925	Aldosterone synthesis and secretion	24/781	105/7206	0.000351234897612
ko05162	Measles	3/781	120/7206	0.000996173469152
ko04966	Collecting duct acid secretion	9/781	26/7206	0.00111825252643
ko05205	Proteoglycans in cancer	14/781	271/7206	0.001326938565
ko05166	HTLV-I infection	16/781	292/7206	0.00146792682524
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/781	79/7206	0.00172389459344
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/781	182/7206	0.00243130273456
ko04141	Protein processing in endoplasmic reticulum	8/781	184/7206	0.0024442096493
ko04621	NOD-like receptor signaling pathway	6/781	157/7206	0.00251989820056
ko04260	Cardiac muscle contraction	21/781	98/7206	0.00261080939018
ko03008	Ribosome biogenesis in eukaryotes	1/781	79/7206	0.00279318044299
ko05169	Epstein-Barr virus infection	10/781	206/7206	0.00298351600538
ko04072	Phospholipase D signaling pathway	35/781	197/7206	0.00334569543976
ko04540	Gap junction	25/781	128/7206	0.00356882950395
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/781	59/7206	0.00459315246631
ko04360	Axon guidance	39/781	233/7206	0.00513155602125
ko04146	Peroxisome	2/781	89/7206	0.00516547123016
ko04745	Phototransduction - fly	10/781	38/7206	0.00591129879509
ko04915	Estrogen signaling pathway	24/781	131/7206	0.00981283610074
ko04964	Proximal tubule bicarbonate reclamation	8/781	29/7206	0.00991730272138
ko04140	Autophagy - animal	8/781	164/7206	0.0104863599791
ko00561	Glycerolipid metabolism	1/781	63/7206	0.0126361507075
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/781	14/7206	0.0128195035334
ko05161	Hepatitis B	9/781	173/7206	0.0128452434707
ko04640	Hematopoietic cell lineage	1/781	64/7206	0.0130569562012
ko04110	Cell cycle	7/781	145/7206	0.0147416999229
ko05140	Leishmaniasis	2/781	75/7206	0.0148432581816
ko04612	Antigen processing and presentation	2/781	77/7206	0.0150389743068
ko04630	Jak-STAT signaling pathway	6/781	132/7206	0.0155939833003
ko04014	Ras signaling pathway	43/781	279/7206	0.0178484065757
ko00310	Lysine degradation	2/781	73/7206	0.0213868629574
ko00564	Glycerophospholipid metabolism	4/781	99/7206	0.022509661826
ko05034	Alcoholism	37/781	238/7206	0.0251871234616
ko00280	Valine, leucine and isoleucine degradation	1/781	54/7206	0.0265014109447
ko00480	Glutathione metabolism	1/781	55/7206	0.0268417809539
ko05321	Inflammatory bowel disease (IBD)	1/781	56/7206	0.0275204734198
ko04976	Bile secretion	15/781	80/7206	0.0291171166285
ko00240	Pyrimidine metabolism	5/781	110/7206	0.029601115004
ko04064	NF-kappa B signaling pathway	4/781	96/7206	0.0308069986375
ko03018	RNA degradation	3/781	84/7206	0.0318706960109
ko04062	Chemokine signaling pathway	31/781	201/7206	0.0382583523646
ko04973	Carbohydrate digestion and absorption	9/781	42/7206	0.0410306431407
ko05110	Vibrio cholerae infection	12/781	63/7206	0.0420047751342
ko04930	Type II diabetes mellitus	11/781	54/7206	0.0430132408563
ko01200	Carbon metabolism	7/781	128/7206	0.0449127499353
ko05414	Dilated cardiomyopathy	19/781	112/7206	0.0449624234103
ko04218	Cellular senescence	11/781	177/7206	0.0490552452093
ko04217	Necroptosis	11/781	178/7206	0.0494583666751