ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 23/458 68/7206 9.53857693726e-12 ko04550 Signaling pathways regulating pluripotency of stem cells 36/458 165/7206 3.04538573415e-11 ko03040 Spliceosome 29/458 145/7206 2.20693364698e-08 ko04340 Hedgehog signaling pathway 17/458 58/7206 5.83740045546e-08 ko04390 Hippo signaling pathway 32/458 188/7206 2.22836811119e-07 ko04330 Notch signaling pathway 16/458 62/7206 9.8139548375e-07 ko04310 Wnt signaling pathway 29/458 181/7206 2.9906002492e-06 ko04144 Endocytosis 4/458 342/7206 3.55702455746e-06 ko04080 Neuroactive ligand-receptor interaction 7/458 423/7206 4.38233187293e-06 ko04950 Maturity onset diabetes of the young 10/458 29/7206 6.51875740029e-06 ko03015 mRNA surveillance pathway 18/458 93/7206 1.7412693518e-05 ko04110 Cell cycle 23/458 145/7206 3.76046224922e-05 ko05224 Breast cancer 26/458 174/7206 4.4031409696e-05 ko04072 Phospholipase D signaling pathway 1/458 197/7206 4.59520793345e-05 ko05010 Alzheimer's disease 1/458 202/7206 4.81991879381e-05 ko03410 Base excision repair 10/458 38/7206 9.15538630689e-05 ko04391 Hippo signaling pathway - fly 16/458 90/7206 0.000147253855482 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/458 182/7206 0.000150984905088 ko04020 Calcium signaling pathway 4/458 265/7206 0.000259679612697 ko04111 Cell cycle - yeast 15/458 90/7206 0.00048761861737 ko04360 Axon guidance 29/458 233/7206 0.000502468871811 ko05012 Parkinson's disease 1/458 155/7206 0.000692471853529 ko04060 Cytokine-cytokine receptor interaction 2/458 191/7206 0.000724417641964 ko04724 Glutamatergic synapse 1/458 152/7206 0.00105868511548 ko04921 Oxytocin signaling pathway 3/458 209/7206 0.00127131535362 ko04723 Retrograde endocannabinoid signaling 2/458 175/7206 0.0014297172281 ko04062 Chemokine signaling pathway 3/458 201/7206 0.00175966895104 ko04910 Insulin signaling pathway 2/458 172/7206 0.0021505005661 ko04612 Antigen processing and presentation 12/458 77/7206 0.00314271960615 ko04113 Meiosis - yeast 11/458 70/7206 0.00431695600322 ko00190 Oxidative phosphorylation 1/458 127/7206 0.00483027441538 ko04141 Protein processing in endoplasmic reticulum 3/458 184/7206 0.00507456196266 ko05202 Transcriptional misregulation in cancer 22/458 188/7206 0.00557436885815 ko04371 Apelin signaling pathway 3/458 177/7206 0.0070381171767 ko03030 DNA replication 7/458 38/7206 0.00903739277456 ko04727 GABAergic synapse 1/458 110/7206 0.00980561973508 ko05032 Morphine addiction 1/458 110/7206 0.00980561973508 ko04070 Phosphatidylinositol signaling system 1/458 112/7206 0.00988354825601 ko05414 Dilated cardiomyopathy 1/458 112/7206 0.00988354825601 ko00514 Other types of O-glycan biosynthesis 6/458 30/7206 0.0102494306069 ko05206 MicroRNAs in cancer 20/458 177/7206 0.0114472124235 ko05231 Choline metabolism in cancer 2/458 134/7206 0.0120070436794 ko04725 Cholinergic synapse 3/458 160/7206 0.0131641221953 ko04915 Estrogen signaling pathway 2/458 131/7206 0.0171835658585 ko04621 NOD-like receptor signaling pathway 3/458 157/7206 0.0188033322046 ko04650 Natural killer cell mediated cytotoxicity 1/458 97/7206 0.0206297505 ko04260 Cardiac muscle contraction 1/458 98/7206 0.0206383449183 ko04971 Gastric acid secretion 1/458 98/7206 0.0206383449183 ko05100 Bacterial invasion of epithelial cells 1/458 99/7206 0.0207338330558 ko05410 Hypertrophic cardiomyopathy (HCM) 1/458 100/7206 0.0209163567677 ko05205 Proteoglycans in cancer 27/458 271/7206 0.0211994751286 ko04211 Longevity regulating pathway 2/458 123/7206 0.0239879458511 ko05166 HTLV-I infection 28/458 292/7206 0.026816731493 ko04341 Hedgehog signaling pathway - fly 6/458 38/7206 0.0310980949187 ko03020 RNA polymerase 5/458 29/7206 0.0339596901502 ko04611 Platelet activation 4/458 163/7206 0.0341688527503 ko05200 Pathways in cancer 43/458 492/7206 0.0344692497127 ko04350 TGF-beta signaling pathway 12/458 103/7206 0.038490282214 ko04662 B cell receptor signaling pathway 1/458 88/7206 0.0439871537012 ko04012 ErbB signaling pathway 2/458 109/7206 0.0471250438473 ko04630 Jak-STAT signaling pathway 3/458 132/7206 0.0475855232822 ko04713 Circadian entrainment 3/458 136/7206 0.0483313165528 ko04931 Insulin resistance 3/458 137/7206 0.0488012021684 ko04013 MAPK signaling pathway - fly 13/458 115/7206 0.0498754850546