ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 31/210 191/7206 2.39808225239e-15 ko05340 Primary immunodeficiency 14/210 30/7206 1.99554257051e-14 ko04650 Natural killer cell mediated cytotoxicity 21/210 97/7206 2.99311229394e-13 ko04612 Antigen processing and presentation 18/210 77/7206 3.98847257868e-12 ko05330 Allograft rejection 11/210 24/7206 1.77720304989e-11 ko05140 Leishmaniasis 17/210 75/7206 2.75927088995e-11 ko04659 Th17 cell differentiation 19/210 106/7206 1.42350456071e-10 ko05321 Inflammatory bowel disease (IBD) 14/210 56/7206 4.07586591481e-10 ko05332 Graft-versus-host disease 9/210 18/7206 4.95209273174e-10 ko04640 Hematopoietic cell lineage 14/210 64/7206 2.734243476e-09 ko05145 Toxoplasmosis 19/210 126/7206 3.02676375882e-09 ko05152 Tuberculosis 23/210 187/7206 3.72917977166e-09 ko05320 Autoimmune thyroid disease 10/210 29/7206 4.40715612871e-09 ko05162 Measles 18/210 120/7206 8.76482361201e-09 ko05150 Staphylococcus aureus infection 10/210 36/7206 4.67737945164e-08 ko04380 Osteoclast differentiation 18/210 134/7206 5.15833674724e-08 ko04658 Th1 and Th2 cell differentiation 15/210 96/7206 9.16151190682e-08 ko04940 Type I diabetes mellitus 9/210 32/7206 2.00196626162e-07 ko05168 Herpes simplex infection 20/210 182/7206 2.73635152229e-07 ko05164 Influenza A 19/210 167/7206 3.20237368347e-07 ko04630 Jak-STAT signaling pathway 16/210 132/7206 1.21445490327e-06 ko04660 T cell receptor signaling pathway 15/210 124/7206 2.71443484369e-06 ko04145 Phagosome 17/210 162/7206 4.24061824784e-06 ko05144 Malaria 9/210 45/7206 4.5495802931e-06 ko05310 Asthma 6/210 17/7206 5.39671915191e-06 ko04062 Chemokine signaling pathway 19/210 201/7206 5.42672270375e-06 ko04064 NF-kappa B signaling pathway 12/210 96/7206 1.98518092684e-05 ko03050 Proteasome 9/210 54/7206 2.17439055169e-05 ko04672 Intestinal immune network for IgA production 7/210 37/7206 7.89996133374e-05 ko04514 Cell adhesion molecules (CAMs) 13/210 130/7206 9.76136718905e-05 ko05416 Viral myocarditis 8/210 55/7206 0.000170515716981 ko05133 Pertussis 10/210 87/7206 0.000201167054929 ko05323 Rheumatoid arthritis 10/210 89/7206 0.000243053924084 ko04620 Toll-like receptor signaling pathway 10/210 100/7206 0.000626367713092 ko04217 Necroptosis 14/210 178/7206 0.000661854275184 ko04666 Fc gamma R-mediated phagocytosis 11/210 122/7206 0.000817239593353 ko04611 Platelet activation 13/210 163/7206 0.000902874246471 ko05142 Chagas disease (American trypanosomiasis) 11/210 130/7206 0.00138156817643 ko04664 Fc epsilon RI signaling pathway 8/210 77/7206 0.0017037277413 ko04610 Complement and coagulation cascades 8/210 79/7206 0.0020100793195 ko04621 NOD-like receptor signaling pathway 12/210 157/7206 0.00203662656125 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/210 191/7206 0.00373388088826 ko04662 B cell receptor signaling pathway 8/210 88/7206 0.00396284690726 ko00511 Other glycan degradation 4/210 26/7206 0.00633231065696 ko04670 Leukocyte transendothelial migration 10/210 151/7206 0.0125757724117 ko05143 African trypanosomiasis 4/210 32/7206 0.0132985985688 ko04360 Axon guidance 1/210 233/7206 0.0154359585241 ko05034 Alcoholism 1/210 238/7206 0.0160592031919 ko00590 Arachidonic acid metabolism 5/210 52/7206 0.0171539067987 ko05161 Hepatitis B 11/210 173/7206 0.0177043034754 ko05016 Huntington's disease 1/210 215/7206 0.0219298980945 ko05132 Salmonella infection 7/210 98/7206 0.0238859842653 ko05146 Amoebiasis 7/210 99/7206 0.0250912373425 ko04072 Phospholipase D signaling pathway 11/210 197/7206 0.0314708794524 ko04622 RIG-I-like receptor signaling pathway 5/210 62/7206 0.0338803440329 ko05322 Systemic lupus erythematosus 9/210 151/7206 0.0429633280834 ko04150 mTOR signaling pathway 1/210 184/7206 0.0453133033309 ko04141 Protein processing in endoplasmic reticulum 1/210 184/7206 0.0453133033309 ko00230 Purine metabolism 1/210 194/7206 0.0468624217932