ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	36/788	56/7206	1.10472441293e-21
ko04724	Glutamatergic synapse	59/788	152/7206	1.12057045647e-19
ko04727	GABAergic synapse	47/788	110/7206	6.94827373675e-18
ko05032	Morphine addiction	47/788	110/7206	6.94827373675e-18
ko04721	Synaptic vesicle cycle	38/788	80/7206	1.4098228747e-16
ko04713	Circadian entrainment	47/788	136/7206	1.17434633662e-13
ko04360	Axon guidance	65/788	233/7206	2.52361300941e-13
ko04728	Dopaminergic synapse	56/788	185/7206	3.070981705e-13
ko04723	Retrograde endocannabinoid signaling	53/788	175/7206	1.33238260111e-12
ko04725	Cholinergic synapse	50/788	160/7206	1.57806163637e-12
ko04024	cAMP signaling pathway	71/788	279/7206	2.79376993677e-12
ko04080	Neuroactive ligand-receptor interaction	94/788	423/7206	5.21025608705e-12
ko04261	Adrenergic signaling in cardiomyocytes	53/788	205/7206	9.95732482573e-10
ko04911	Insulin secretion	35/788	117/7206	1.34892077874e-08
ko04514	Cell adhesion molecules (CAMs)	35/788	130/7206	2.48874896458e-07
ko03040	Spliceosome	1/788	145/7206	1.31034930747e-06
ko04744	Phototransduction	15/788	36/7206	2.04657925364e-06
ko05203	Viral carcinogenesis	9/788	277/7206	2.94007273293e-06
ko05030	Cocaine addiction	22/788	73/7206	5.93723800765e-06
ko04726	Serotonergic synapse	33/788	137/7206	9.89131711271e-06
ko04742	Taste transduction	19/788	61/7206	1.50984079864e-05
ko04970	Salivary secretion	25/788	95/7206	1.9929180203e-05
ko05164	Influenza A	4/788	167/7206	4.76653231927e-05
ko05322	Systemic lupus erythematosus	3/788	151/7206	5.43318104069e-05
ko05168	Herpes simplex infection	5/788	182/7206	5.72099443161e-05
ko03013	RNA transport	4/788	166/7206	7.02438531155e-05
ko04921	Oxytocin signaling pathway	41/788	209/7206	0.000170554745279
ko04391	Hippo signaling pathway - fly	22/788	90/7206	0.000229602584073
ko05031	Amphetamine addiction	22/788	91/7206	0.000264050523038
ko04730	Long-term depression	20/788	78/7206	0.00030848926897
ko04010	MAPK signaling pathway	56/788	321/7206	0.000327213947106
ko04022	cGMP-PKG signaling pathway	41/788	216/7206	0.00034852194692
ko05205	Proteoglycans in cancer	13/788	271/7206	0.000461942319407
ko04964	Proximal tubule bicarbonate reclamation	10/788	29/7206	0.000662430069542
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/788	79/7206	0.000770079013376
ko04120	Ubiquitin mediated proteolysis	4/788	138/7206	0.000810767934141
ko04020	Calcium signaling pathway	46/788	265/7206	0.00125329103007
ko04621	NOD-like receptor signaling pathway	6/788	157/7206	0.00179420139298
ko04972	Pancreatic secretion	23/788	111/7206	0.00201137625268
ko01200	Carbon metabolism	4/788	128/7206	0.00231604361163
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/788	14/7206	0.00232424782863
ko05014	Amyotrophic lateral sclerosis (ALS)	17/788	74/7206	0.0023383478045
ko04141	Protein processing in endoplasmic reticulum	8/788	184/7206	0.00249414792447
ko04260	Cardiac muscle contraction	21/788	98/7206	0.00270984380253
ko00240	Pyrimidine metabolism	3/788	110/7206	0.00293920432667
ko04060	Cytokine-cytokine receptor interaction	9/788	191/7206	0.00312911714574
ko04214	Apoptosis - fly	1/788	72/7206	0.0038466682808
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/788	59/7206	0.00481990721498
ko04971	Gastric acid secretion	20/788	98/7206	0.00503276146838
ko04966	Collecting duct acid secretion	8/788	26/7206	0.00510917104329
ko04720	Long-term potentiation	20/788	99/7206	0.00546876399347
ko05169	Epstein-Barr virus infection	11/788	206/7206	0.00636418042994
ko04930	Type II diabetes mellitus	13/788	54/7206	0.00640600275827
ko04137	Mitophagy - animal	2/788	82/7206	0.00720643187071
ko03018	RNA degradation	2/788	84/7206	0.00732155468088
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/788	182/7206	0.0075737302385
ko04217	Necroptosis	9/788	178/7206	0.00999259682168
ko05162	Measles	5/788	120/7206	0.0118202602811
ko05414	Dilated cardiomyopathy	21/788	112/7206	0.013405972368
ko04924	Renin secretion	17/788	86/7206	0.0137591495244
ko05140	Leishmaniasis	2/788	75/7206	0.0147888184268
ko00515	Mannose type O-glycan biosynthesis	7/788	25/7206	0.0149838660345
ko04146	Peroxisome	3/788	89/7206	0.0159967005193
ko04390	Hippo signaling pathway	31/788	188/7206	0.0175256259546
ko04072	Phospholipase D signaling pathway	32/788	197/7206	0.0201563445202
ko04973	Carbohydrate digestion and absorption	10/788	42/7206	0.0207357438302
ko04915	Estrogen signaling pathway	23/788	131/7206	0.0224351537981
ko05110	Vibrio cholerae infection	13/788	63/7206	0.0228451377439
ko04925	Aldosterone synthesis and secretion	19/788	105/7206	0.0259471033534
ko04810	Regulation of actin cytoskeleton	18/788	264/7206	0.0268729327648
ko00480	Glutathione metabolism	1/788	55/7206	0.0270556249717
ko04371	Apelin signaling pathway	29/788	177/7206	0.0270983584911
ko04512	ECM-receptor interaction	15/788	79/7206	0.028491331752
ko04064	NF-kappa B signaling pathway	4/788	96/7206	0.0309028154966
ko05131	Shigellosis	3/788	82/7206	0.0312328124308
ko05012	Parkinson's disease	9/788	155/7206	0.0368900629187
ko04960	Aldosterone-regulated sodium reabsorption	9/788	41/7206	0.0386797690868
ko00590	Arachidonic acid metabolism	1/788	52/7206	0.0403706081518
ko04071	Sphingolipid signaling pathway	26/788	162/7206	0.0410913167577
ko00561	Glycerolipid metabolism	2/788	63/7206	0.0425090419862
ko04640	Hematopoietic cell lineage	2/788	64/7206	0.0426265906097
ko04612	Antigen processing and presentation	3/788	77/7206	0.0430674389219
ko04014	Ras signaling pathway	41/788	279/7206	0.0495839113267