ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05032	Morphine addiction	25/464	110/7206	1.880645257e-08
ko04024	cAMP signaling pathway	40/464	279/7206	1.23670535074e-06
ko04020	Calcium signaling pathway	38/464	265/7206	2.38984206952e-06
ko04724	Glutamatergic synapse	26/464	152/7206	3.60782546636e-06
ko04080	Neuroactive ligand-receptor interaction	52/464	423/7206	4.92955321238e-06
ko04070	Phosphatidylinositol signaling system	21/464	112/7206	7.24128401771e-06
ko04710	Circadian rhythm	12/464	43/7206	1.0772714975e-05
ko04727	GABAergic synapse	20/464	110/7206	1.92342344252e-05
ko04725	Cholinergic synapse	25/464	160/7206	2.81780079555e-05
ko05033	Nicotine addiction	13/464	56/7206	4.04982486562e-05
ko04713	Circadian entrainment	21/464	136/7206	0.000145647909158
ko04921	Oxytocin signaling pathway	28/464	209/7206	0.000250788089269
ko04726	Serotonergic synapse	21/464	137/7206	0.000262134507736
ko04744	Phototransduction	9/464	36/7206	0.000346313951296
ko05031	Amphetamine addiction	15/464	91/7206	0.000631090523289
ko04925	Aldosterone synthesis and secretion	16/464	105/7206	0.00102126358893
ko04728	Dopaminergic synapse	24/464	185/7206	0.00111900338306
ko04922	Glucagon signaling pathway	18/464	128/7206	0.00151063072048
ko03040	Spliceosome	1/464	145/7206	0.00158707705442
ko03013	RNA transport	2/464	166/7206	0.00203963560791
ko03010	Ribosome	1/464	129/7206	0.00318434688102
ko04960	Aldosterone-regulated sodium reabsorption	8/464	41/7206	0.00402853118931
ko05230	Central carbon metabolism in cancer	12/464	81/7206	0.00532881646323
ko04014	Ras signaling pathway	30/464	279/7206	0.00567715167167
ko04110	Cell cycle	2/464	145/7206	0.00593863802477
ko00562	Inositol phosphate metabolism	13/464	89/7206	0.00687963938418
ko04750	Inflammatory mediator regulation of TRP channels	16/464	122/7206	0.00754300634477
ko04152	AMPK signaling pathway	19/464	161/7206	0.00881162269237
ko04745	Phototransduction - fly	7/464	38/7206	0.00967865372564
ko00230	Purine metabolism	22/464	194/7206	0.0105565964719
ko04971	Gastric acid secretion	13/464	98/7206	0.0111247491567
ko04911	Insulin secretion	15/464	117/7206	0.0113819778895
ko04723	Retrograde endocannabinoid signaling	20/464	175/7206	0.0115285576062
ko04720	Long-term potentiation	13/464	99/7206	0.0118689994968
ko04120	Ubiquitin mediated proteolysis	2/464	138/7206	0.0125158527072
ko04066	HIF-1 signaling pathway	15/464	123/7206	0.0146784693889
ko04923	Regulation of lipolysis in adipocytes	11/464	77/7206	0.0155965792688
ko00051	Fructose and mannose metabolism	7/464	42/7206	0.0165865112071
ko00680	Methane metabolism	6/464	34/7206	0.019863771966
ko04930	Type II diabetes mellitus	8/464	54/7206	0.0211472299936
ko04919	Thyroid hormone signaling pathway	16/464	143/7206	0.0251684509675
ko04626	Plant-pathogen interaction	4/464	18/7206	0.02521241852
ko04072	Phospholipase D signaling pathway	21/464	197/7206	0.0255280945121
ko00010	Glycolysis / Gluconeogenesis	10/464	74/7206	0.0265457089455
ko04650	Natural killer cell mediated cytotoxicity	12/464	97/7206	0.032930172663
ko04022	cGMP-PKG signaling pathway	22/464	216/7206	0.0330911038339
ko00564	Glycerophospholipid metabolism	12/464	99/7206	0.0349492992482
ko04740	Olfactory transduction	10/464	80/7206	0.0364688865496
ko04211	Longevity regulating pathway	14/464	123/7206	0.0381600967655
ko04360	Axon guidance	23/464	233/7206	0.0402868312807
ko04711	Circadian rhythm - fly	3/464	13/7206	0.04676000553