ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 27/378 68/7206 1.0341657691e-17 ko04390 Hippo signaling pathway 36/378 188/7206 6.1020309658e-12 ko05224 Breast cancer 33/378 174/7206 6.3911920896e-11 ko05205 Proteoglycans in cancer 39/378 271/7206 5.62156972162e-09 ko04110 Cell cycle 27/378 145/7206 5.71107851678e-09 ko04550 Signaling pathways regulating pluripotency of stem cells 29/378 165/7206 6.1200217584e-09 ko05200 Pathways in cancer 57/378 492/7206 6.87112739945e-09 ko04310 Wnt signaling pathway 30/378 181/7206 1.37356176491e-08 ko04080 Neuroactive ligand-receptor interaction 2/378 423/7206 3.24215755326e-08 ko03030 DNA replication 11/378 38/7206 2.38754221149e-06 ko05166 HTLV-I infection 34/378 292/7206 1.02402385199e-05 ko03040 Spliceosome 21/378 145/7206 1.92424043858e-05 ko04340 Hedgehog signaling pathway 12/378 58/7206 3.61917449627e-05 ko04111 Cell cycle - yeast 15/378 90/7206 5.86803092575e-05 ko04916 Melanogenesis 19/378 142/7206 0.000142702202706 ko03008 Ribosome biogenesis in eukaryotes 13/378 79/7206 0.000207486569622 ko04612 Antigen processing and presentation 12/378 77/7206 0.000604989191726 ko04020 Calcium signaling pathway 3/378 265/7206 0.000629277218177 ko05222 Small cell lung cancer 13/378 89/7206 0.000686717252366 ko04392 Hippo signaling pathway -multiple species 7/378 31/7206 0.000908579049261 ko04113 Meiosis - yeast 11/378 70/7206 0.000944621763727 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/378 182/7206 0.00107183567225 ko03013 RNA transport 19/378 166/7206 0.00116902399174 ko05202 Transcriptional misregulation in cancer 21/378 188/7206 0.00120968509531 ko04360 Axon guidance 24/378 233/7206 0.00141014271746 ko04022 cGMP-PKG signaling pathway 2/378 216/7206 0.0015518136471 ko03420 Nucleotide excision repair 8/378 46/7206 0.00240018357088 ko04350 TGF-beta signaling pathway 13/378 103/7206 0.00269142655385 ko04072 Phospholipase D signaling pathway 2/378 197/7206 0.00304403948423 ko03410 Base excision repair 7/378 38/7206 0.00317728559367 ko04621 NOD-like receptor signaling pathway 1/378 157/7206 0.00329327842593 ko04950 Maturity onset diabetes of the young 6/378 29/7206 0.0033982586245 ko05218 Melanoma 11/378 85/7206 0.0046100478034 ko04330 Notch signaling pathway 9/378 62/7206 0.0046887903894 ko05012 Parkinson's disease 1/378 155/7206 0.00510671480488 ko04921 Oxytocin signaling pathway 3/378 209/7206 0.00694506891058 ko04391 Hippo signaling pathway - fly 11/378 90/7206 0.00711887001366 ko04062 Chemokine signaling pathway 3/378 201/7206 0.00968367184418 ko05231 Choline metabolism in cancer 1/378 134/7206 0.0101163225001 ko04931 Insulin resistance 1/378 137/7206 0.0103146530387 ko04024 cAMP signaling pathway 6/378 279/7206 0.0132875440739 ko01200 Carbon metabolism 1/378 128/7206 0.0147621240447 ko00240 Pyrimidine metabolism 12/378 110/7206 0.0148037562103 ko05206 MicroRNAs in cancer 17/378 177/7206 0.015178564997 ko04630 Jak-STAT signaling pathway 1/378 132/7206 0.0155106113312 ko00670 One carbon pool by folate 4/378 20/7206 0.0184966654402 ko04144 Endocytosis 9/378 342/7206 0.0244950937532 ko04724 Glutamatergic synapse 2/378 152/7206 0.0250373347288 ko04217 Necroptosis 3/378 178/7206 0.0257829153853 ko03015 mRNA surveillance pathway 10/378 93/7206 0.0297266430326 ko04727 GABAergic synapse 1/378 110/7206 0.0305539157267 ko05032 Morphine addiction 1/378 110/7206 0.0305539157267 ko05010 Alzheimer's disease 4/378 202/7206 0.0353974946503 ko04723 Retrograde endocannabinoid signaling 3/378 175/7206 0.0366740576534 ko01522 Endocrine resistance 12/378 124/7206 0.0383657287323 ko04150 mTOR signaling pathway 16/378 184/7206 0.0426899124825 ko04341 Hedgehog signaling pathway - fly 5/378 38/7206 0.0467539830173 ko04725 Cholinergic synapse 3/378 160/7206 0.0484471578569 ko04152 AMPK signaling pathway 3/378 161/7206 0.0484561686582