ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	165/1129	423/7206	1.8846966437e-33
ko04724	Glutamatergic synapse	81/1129	152/7206	1.89411997824e-27
ko05033	Nicotine addiction	41/1129	56/7206	7.7751587642e-22
ko05032	Morphine addiction	60/1129	110/7206	2.80139920826e-21
ko04727	GABAergic synapse	59/1129	110/7206	1.86836020055e-20
ko04728	Dopaminergic synapse	80/1129	185/7206	1.15955096474e-19
ko04713	Circadian entrainment	66/1129	136/7206	1.17161787623e-19
ko04721	Synaptic vesicle cycle	46/1129	80/7206	8.03557207999e-18
ko04725	Cholinergic synapse	68/1129	160/7206	2.13388653857e-16
ko04723	Retrograde endocannabinoid signaling	71/1129	175/7206	8.86585015561e-16
ko04024	cAMP signaling pathway	97/1129	279/7206	1.14455046916e-15
ko04911	Insulin secretion	51/1129	117/7206	4.01070682809e-13
ko04921	Oxytocin signaling pathway	74/1129	209/7206	1.08891948632e-12
ko04020	Calcium signaling pathway	87/1129	265/7206	1.42819229511e-12
ko04726	Serotonergic synapse	54/1129	137/7206	1.05894141794e-11
ko05031	Amphetamine addiction	41/1129	91/7206	2.3050723839e-11
ko04742	Taste transduction	30/1129	61/7206	8.25988034732e-10
ko04720	Long-term potentiation	40/1129	99/7206	2.21983615305e-09
ko04744	Phototransduction	21/1129	36/7206	5.4543154744e-09
ko03010	Ribosome	1/1129	129/7206	1.08622981954e-08
ko04925	Aldosterone synthesis and secretion	39/1129	105/7206	7.08255009942e-08
ko04261	Adrenergic signaling in cardiomyocytes	62/1129	205/7206	8.82470536319e-08
ko03040	Spliceosome	3/1129	145/7206	9.42701848376e-08
ko04022	cGMP-PKG signaling pathway	64/1129	216/7206	1.69519010236e-07
ko05322	Systemic lupus erythematosus	4/1129	151/7206	3.2626536892e-07
ko04970	Salivary secretion	35/1129	95/7206	4.21750646837e-07
ko05030	Cocaine addiction	29/1129	73/7206	5.54294970782e-07
ko04971	Gastric acid secretion	34/1129	98/7206	3.42460944768e-06
ko04966	Collecting duct acid secretion	14/1129	26/7206	7.48044993918e-06
ko04070	Phosphatidylinositol signaling system	36/1129	112/7206	1.0403971652e-05
ko04730	Long-term depression	28/1129	78/7206	1.05479541176e-05
ko03013	RNA transport	8/1129	166/7206	1.90656927643e-05
ko04010	MAPK signaling pathway	79/1129	321/7206	1.97269398079e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1129	74/7206	3.19517070483e-05
ko04514	Cell adhesion molecules (CAMs)	39/1129	130/7206	4.14296745708e-05
ko04972	Pancreatic secretion	34/1129	111/7206	5.9549274013e-05
ko05203	Viral carcinogenesis	21/1129	277/7206	6.53675445293e-05
ko04110	Cell cycle	7/1129	145/7206	6.96466000377e-05
ko04915	Estrogen signaling pathway	38/1129	131/7206	8.52293804248e-05
ko05168	Herpes simplex infection	11/1129	182/7206	0.000110152363094
ko04710	Circadian rhythm	17/1129	43/7206	0.000132863627897
ko04961	Endocrine and other factor-regulated calcium reabsorption	21/1129	59/7206	0.000175883311424
ko04141	Protein processing in endoplasmic reticulum	12/1129	184/7206	0.00019688467507
ko04072	Phospholipase D signaling pathway	51/1129	197/7206	0.000202365224067
ko03008	Ribosome biogenesis in eukaryotes	2/1129	79/7206	0.00026678767044
ko04745	Phototransduction - fly	15/1129	38/7206	0.000334637321843
ko04120	Ubiquitin mediated proteolysis	8/1129	138/7206	0.000536383002839
ko04750	Inflammatory mediator regulation of TRP channels	34/1129	122/7206	0.000576057684492
ko05110	Vibrio cholerae infection	21/1129	63/7206	0.000648186701665
ko04371	Apelin signaling pathway	45/1129	177/7206	0.000720419678524
ko04360	Axon guidance	55/1129	233/7206	0.00126766739521
ko04014	Ras signaling pathway	64/1129	279/7206	0.00132818474701
ko00280	Valine, leucine and isoleucine degradation	1/1129	54/7206	0.00206304631703
ko00520	Amino sugar and nucleotide sugar metabolism	1/1129	55/7206	0.00217594991241
ko04922	Glucagon signaling pathway	33/1129	128/7206	0.00294628668403
ko04626	Plant-pathogen interaction	8/1129	18/7206	0.00355798185792
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/1129	79/7206	0.00480646751274
ko04260	Cardiac muscle contraction	26/1129	98/7206	0.00486367001573
ko04666	Fc gamma R-mediated phagocytosis	31/1129	122/7206	0.00526336793508
ko04015	Rap1 signaling pathway	61/1129	278/7206	0.00529218393301
ko04540	Gap junction	32/1129	128/7206	0.00643547144
ko05164	Influenza A	14/1129	167/7206	0.00686370609963
ko03420	Nucleotide excision repair	1/1129	46/7206	0.00692602511678
ko04924	Renin secretion	23/1129	86/7206	0.00698917990879
ko04612	Antigen processing and presentation	4/1129	77/7206	0.00704468807495
ko04146	Peroxisome	5/1129	89/7206	0.00744108554233
ko04930	Type II diabetes mellitus	16/1129	54/7206	0.0079722324129
ko04960	Aldosterone-regulated sodium reabsorption	13/1129	41/7206	0.00864903059917
ko04350	TGF-beta signaling pathway	7/1129	103/7206	0.00921859381945
ko04711	Circadian rhythm - fly	6/1129	13/7206	0.00928803003756
ko04115	p53 signaling pathway	4/1129	74/7206	0.00990193127256
ko00240	Pyrimidine metabolism	8/1129	110/7206	0.0116588789286
ko04976	Bile secretion	21/1129	80/7206	0.0128443707002
ko04270	Vascular smooth muscle contraction	36/1129	154/7206	0.013076506094
ko04623	Cytosolic DNA-sensing pathway	1/1129	41/7206	0.0155869871933
ko04918	Thyroid hormone synthesis	22/1129	86/7206	0.0161057246464
ko04923	Regulation of lipolysis in adipocytes	20/1129	77/7206	0.0173931648147
ko05414	Dilated cardiomyopathy	27/1129	112/7206	0.0178440114474
ko05231	Choline metabolism in cancer	31/1129	134/7206	0.0219836227495
ko05162	Measles	10/1129	120/7206	0.0225225695751
ko04672	Intestinal immune network for IgA production	1/1129	37/7206	0.0227188691097
ko04650	Natural killer cell mediated cytotoxicity	24/1129	97/7206	0.0231529243539
ko05133	Pertussis	6/1129	87/7206	0.0246449993816
ko04662	B cell receptor signaling pathway	22/1129	88/7206	0.0253617118028
ko05130	Pathogenic Escherichia coli infection	5/1129	77/7206	0.0259460164365
ko05219	Bladder cancer	2/1129	48/7206	0.0263336599677
ko05323	Rheumatoid arthritis	22/1129	89/7206	0.026394859167
ko00562	Inositol phosphate metabolism	22/1129	89/7206	0.026394859167
ko04740	Olfactory transduction	20/1129	80/7206	0.0290370628654
ko04973	Carbohydrate digestion and absorption	12/1129	42/7206	0.0308147640302
ko05169	Epstein-Barr virus infection	21/1129	206/7206	0.0317494972226
ko05161	Hepatitis B	17/1129	173/7206	0.0336330875974
ko00860	Porphyrin and chlorophyll metabolism	1/1129	34/7206	0.0338579466637
ko00310	Lysine degradation	5/1129	73/7206	0.0349048940073
ko04964	Proximal tubule bicarbonate reclamation	9/1129	29/7206	0.0357316402863
ko00071	Fatty acid degradation	2/1129	45/7206	0.0376562146915
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/1129	92/7206	0.0415804670889
ko04113	Meiosis - yeast	5/1129	70/7206	0.0472883010133
ko04071	Sphingolipid signaling pathway	35/1129	162/7206	0.0481195947825
ko04062	Chemokine signaling pathway	42/1129	201/7206	0.0482918626036
ko04214	Apoptosis - fly	5/1129	72/7206	0.0483840601803