ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	179/983	423/7206	2.09143052525e-51
ko04724	Glutamatergic synapse	82/983	152/7206	1.08880430621e-32
ko05032	Morphine addiction	66/983	110/7206	3.23937847137e-30
ko05033	Nicotine addiction	44/983	56/7206	3.96631107955e-28
ko04727	GABAergic synapse	61/983	110/7206	2.11929551709e-25
ko04728	Dopaminergic synapse	77/983	185/7206	1.72497235441e-21
ko04723	Retrograde endocannabinoid signaling	74/983	175/7206	3.51765926124e-21
ko04713	Circadian entrainment	63/983	136/7206	1.08106897173e-20
ko04721	Synaptic vesicle cycle	45/983	80/7206	2.29246235351e-19
ko04725	Cholinergic synapse	67/983	160/7206	5.38804497306e-19
ko04024	cAMP signaling pathway	92/983	279/7206	2.61939298884e-17
ko04726	Serotonergic synapse	56/983	137/7206	1.6831411967e-15
ko04742	Taste transduction	34/983	61/7206	8.98008553799e-15
ko04911	Insulin secretion	48/983	117/7206	1.56177061401e-13
ko04020	Calcium signaling pathway	81/983	265/7206	3.55373542216e-13
ko05031	Amphetamine addiction	38/983	91/7206	2.93232773186e-11
ko04921	Oxytocin signaling pathway	65/983	209/7206	4.76498441388e-11
ko04744	Phototransduction	21/983	36/7206	4.04986620465e-10
ko05030	Cocaine addiction	31/983	73/7206	1.20448401777e-09
ko04261	Adrenergic signaling in cardiomyocytes	61/983	205/7206	1.25487377322e-09
ko04720	Long-term potentiation	36/983	99/7206	8.8956637725e-09
ko03040	Spliceosome	1/983	145/7206	2.34951641808e-08
ko04970	Salivary secretion	32/983	95/7206	4.56907988595e-07
ko04925	Aldosterone synthesis and secretion	34/983	105/7206	7.60334103253e-07
ko04010	MAPK signaling pathway	74/983	321/7206	2.62325515627e-06
ko04072	Phospholipase D signaling pathway	51/983	197/7206	4.03276732463e-06
ko05322	Systemic lupus erythematosus	4/983	151/7206	5.96711293551e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/983	74/7206	7.74344809647e-06
ko04022	cGMP-PKG signaling pathway	53/983	216/7206	1.18020584531e-05
ko05168	Herpes simplex infection	7/983	182/7206	1.48298022539e-05
ko03013	RNA transport	6/983	166/7206	2.75292257041e-05
ko04514	Cell adhesion molecules (CAMs)	35/983	130/7206	4.7497397199e-05
ko04966	Collecting duct acid secretion	12/983	26/7206	5.93270666086e-05
ko04972	Pancreatic secretion	31/983	111/7206	6.42176747709e-05
ko04060	Cytokine-cytokine receptor interaction	9/983	191/7206	6.53343995762e-05
ko04350	TGF-beta signaling pathway	2/983	103/7206	6.55475201306e-05
ko04070	Phosphatidylinositol signaling system	31/983	112/7206	7.31322633648e-05
ko05203	Viral carcinogenesis	17/983	277/7206	7.48916793745e-05
ko04971	Gastric acid secretion	28/983	98/7206	8.38580689679e-05
ko04120	Ubiquitin mediated proteolysis	5/983	138/7206	0.000135262278442
ko04141	Protein processing in endoplasmic reticulum	9/983	184/7206	0.000178692679635
ko03008	Ribosome biogenesis in eukaryotes	1/983	79/7206	0.00020233269309
ko04110	Cell cycle	6/983	145/7206	0.000210622262527
ko05164	Influenza A	8/983	167/7206	0.000233482161238
ko05110	Vibrio cholerae infection	20/983	63/7206	0.000258865619528
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/983	79/7206	0.0003565305143
ko05414	Dilated cardiomyopathy	29/983	112/7206	0.000442136332941
ko04260	Cardiac muscle contraction	26/983	98/7206	0.00056053277417
ko05231	Choline metabolism in cancer	32/983	134/7206	0.00128940420029
ko04014	Ras signaling pathway	57/983	279/7206	0.00130374626097
ko04915	Estrogen signaling pathway	31/983	131/7206	0.00179581605366
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/983	59/7206	0.00187101771345
ko04621	NOD-like receptor signaling pathway	9/983	157/7206	0.00206273061671
ko04730	Long-term depression	21/983	78/7206	0.00225847332366
ko04924	Renin secretion	22/983	86/7206	0.00248431497876
ko04540	Gap junction	30/983	128/7206	0.00249397840224
ko05169	Epstein-Barr virus infection	14/983	206/7206	0.00263422308252
ko05162	Measles	6/983	120/7206	0.00297785197913
ko04360	Axon guidance	47/983	233/7206	0.00473924986086
ko04750	Inflammatory mediator regulation of TRP channels	28/983	122/7206	0.00476573397025
ko04930	Type II diabetes mellitus	15/983	54/7206	0.00493655584991
ko00520	Amino sugar and nucleotide sugar metabolism	1/983	55/7206	0.00503356594072
ko05205	Proteoglycans in cancer	22/983	271/7206	0.00510720055934
ko04550	Signaling pathways regulating pluripotency of stem cells	11/983	165/7206	0.00573861347871
ko05161	Hepatitis B	12/983	173/7206	0.00691531704111
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/983	14/7206	0.00717448621404
ko04612	Antigen processing and presentation	3/983	77/7206	0.0072806671813
ko00240	Pyrimidine metabolism	6/983	110/7206	0.00768407669011
ko04146	Peroxisome	4/983	89/7206	0.00769535153997
ko05140	Leishmaniasis	3/983	75/7206	0.0103470047334
ko04923	Regulation of lipolysis in adipocytes	19/983	77/7206	0.0109024757769
ko05133	Pertussis	4/983	87/7206	0.0109042274905
ko04740	Olfactory transduction	19/983	80/7206	0.0130217583767
ko04976	Bile secretion	19/983	80/7206	0.0130217583767
ko04330	Notch signaling pathway	2/983	62/7206	0.0139063933269
ko04745	Phototransduction - fly	11/983	38/7206	0.0140900727701
ko03420	Nucleotide excision repair	1/983	46/7206	0.0164475836093
ko04666	Fc gamma R-mediated phagocytosis	26/983	122/7206	0.0165057501507
ko05219	Bladder cancer	1/983	48/7206	0.01746751629
ko05410	Hypertrophic cardiomyopathy (HCM)	22/983	100/7206	0.0186373575334
ko00562	Inositol phosphate metabolism	20/983	89/7206	0.0194126892934
ko04371	Apelin signaling pathway	35/983	177/7206	0.0197204021495
ko04217	Necroptosis	14/983	178/7206	0.0200865288799
ko04630	Jak-STAT signaling pathway	9/983	132/7206	0.0203974065518
ko03320	PPAR signaling pathway	3/983	69/7206	0.0206357032947
ko05166	HTLV-I infection	27/983	292/7206	0.0235592109865
ko05215	Prostate cancer	7/983	111/7206	0.0244798087805
ko05144	Malaria	1/983	45/7206	0.0257991337414
ko00071	Fatty acid degradation	1/983	45/7206	0.0257991337414
ko04918	Thyroid hormone synthesis	19/983	86/7206	0.0267924038171
ko04510	Focal adhesion	21/983	240/7206	0.0272026855949
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/983	182/7206	0.0286896224233
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/983	92/7206	0.0310117676834
ko05418	Fluid shear stress and atherosclerosis	14/983	173/7206	0.0324220626225
ko05034	Alcoholism	44/983	238/7206	0.0340021990363
ko04658	Th1 and Th2 cell differentiation	6/983	96/7206	0.0347479281032
ko05145	Toxoplasmosis	9/983	126/7206	0.0349355422163
ko04210	Apoptosis	15/983	180/7206	0.0361017059897
ko04062	Chemokine signaling pathway	38/983	201/7206	0.0363026154669
ko00310	Lysine degradation	4/983	73/7206	0.0390282294388
ko04115	p53 signaling pathway	4/983	74/7206	0.039355205948
ko00590	Arachidonic acid metabolism	2/983	52/7206	0.040094335051
ko04622	RIG-I-like receptor signaling pathway	3/983	62/7206	0.0401802168903
ko00680	Methane metabolism	9/983	34/7206	0.0411937092121
ko05016	Huntington's disease	19/983	215/7206	0.0428284633594
ko04218	Cellular senescence	15/983	177/7206	0.0452338941907
ko05206	MicroRNAs in cancer	15/983	177/7206	0.0452338941907
ko04964	Proximal tubule bicarbonate reclamation	8/983	29/7206	0.0498920094222